Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
COS5
Systematic Name
YJR161C
Strain
S288c
Description
Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>COS5 YJR161C
ATGAAAGAGAATGAACTTAAAAATGAGAAGAGTGTAGATGTATTATCCTTCAAACAGCTC
GAATCCCAAAAGATTGTTCTACCTCAAGATCTTTTCAGAAGCAGCTTTACCTGGTTTTGT
TATGAAATTTACAAGTCCTTAGCGTTTCCGATCTGGATGCTATTATGGCTACCACTTAGC
GTCTGGTGGAAACTTTCCAACAATTGTATTTACCCACTTATAGTTTCACTTCTGGTCCTG
TTTCTGGGACCAATATTTGTCCTTGTTATTTGTGGACTTTCTCGTAAGCGTTCCTTATCG
AAACAACTCATTCAGTTTTGCAAAGAGGTTACTGAAAACACACCAAGTTCTGATCCTCAT
GATTGGGAAGTTGTTGCAGCAAATCTAAATTCGTACTTATATGAAAATAAGGCTTGGAAT
ACTAGGTACTTTTTCTTCAATGCCATGGGCTGCCAAGAAGCGTTCAGAACAACCCTTCTC
GAACCCTTCTCTTTGAAAAAAGACGAAGCTGCCAAGGTTAAGTCATTTAAGGATTCCGTC
CCTTACATTGAAGAAGCATTGGGAGTTTATTTTAGAGAAGTTGAAAAACAATGGAAGTTG
TTTAATACTGAAAAATCATGGAGCCCTGTTGGCCTGGAAGACGTTCAGCTTCCCAAGGAT
ATTCATCGGTCCAAGCTTACTTGGTTTTTAAAGCGGATTTTCACTATTTACTCTCTACCA
TTATGGCTTGCTTTTTTGAACTGTATCTGCGTGTCACAGCATTTTTGCCTTGCATTTCGT
ATATTGTGTCCTGGATTGTTTTTCCTCATGATGGTGTGGCTTTTCCAAAATATGAGGACG
ACTGCTTTACTCGTGAAAATGGAACACAAGATGCAATTCTTGTTGACTATTATAAATGAG
CAAGAAAGTGGTGCGAATGGATGGGACGAAATTGCAAGGAAAATGAATAGGTACTTGTTT
GAGAAAAAAGCCTGGAAGAATGAAGAGTTTTTCTTCGAGGGGATTGACTGTGAATGGTTT
TTTAGCCACTTCTTCTACCGCCTTCTATCTGCAAAGAAATCTATGTGGCTTTTACCATTG
AATGTGGAACTATGGCCATATATTAAAGAAGCGCAATTGTCCCGCAATGAAGAGTCTTTA
ATGAAGAAATGA
Promoter Sequence
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>COS5 YJR161C
TTATATACACTTATGCCAATATTACAAAAAAATCACCACTAAAATCACCTAAACATAAAA
ATATTCTATTCTTCAACCATAATACATAAACACACTTAATTGCGTCTTAATACTATCATG
GTATCATTAACTTAAAGTTCCTTAATATCGTCATACCACTATGCTCTATTCCATATATTG
TAATATAACTGTACTCTATAGTCATACAGACGCTTTTACTTCACCCCATCTTCTCATACT
ATTGTCATAGAATCTCACACTGACGCATGATTAAAACGAATAATTTTTACTGTAAGGGCT
GCCATCCGCGCTCTATCCTTTTGTTTGCAATATTTATATACAGAATCTCAAAACAAGCGG
GAGAAGTGCTAATTACCCAGAGGTCATGCATGATCTGAGTACCACCGTACCTCTAGGTTT
TGTTTTGATCCGTTTTACAGTGACACCGAACATAAGGGGAAGCTATTGACATGGTATCGA
AAGGTTGTCCACATTGGGAAGTAACTTGGTTCTATGAATCTTCATGTCAGATACGTAGGA
CAGACTCTTTCCTGTGTAAATATTTGTGACAGCTACGTCTATTTTCTACTAGATGTTTAC
ACAGTTTTGTCACAGGAAATCTACGCTTAAAATATGTATTTCATTCAAGCGGTAACCGCT
GTACGAGCAGTGACATTGCTGGTCGCACCTTAAATGTAAACCAAAGTTACGGCACACCGT
GATGTACCCGCATTAAAGTTTTGTAAATTCGTTATTACGATTATCGAGTTGGCTAGATAG
AAAACCGGAAATGAAATGGATGCCCTTTTCGAATAGCTGAGTTTCTTTGCCTAAAATAGC
CCAATATTGTTGCCCTTTTTCTATCACGAGGTTACTGAGCCATTGCATGAACGCGCGCGC
CTCGGCGGCTTTTTTTTTCTGCTGTGCTGTATAAAAGCGAAAAGTCAGAAGTTACTATCT
CGAATAAAAAACCCCTCGAACTGCCATCTCACTACCGAAA
Chr coordinates
Chr X from 743999-742848