Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name NFU1
Systematic Name YKL040C
Alias NUB1
Strain S288c
Description Protein involved in Fe-S cluster transfer to mitochondrial clients; protects [4Fe-4S] clusters from damage due to oxidative stress; acts along with Bol3 at a late step in the transfer of [4Fe-4S] clusters from the ISA complex to client proteins; Fe-S loaded homodimer at steady state; similar to NifU, a bacterial protein required for Fe/S cluster maturation; ortholog of the human NFU1, mutations of which are associated with Multiple Mitochondria Dysfunctions Syndrome (MMDS1)
External sources Open in SGD external link
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Gene Sequence
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Promoter Sequence
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>NFU1 YKL040C
CTCATCACTCAATCCACTTATTTTTTTAAGATTGAATGATATAAACGGGTCTATTTTGCC
CTTCCAATCTTCTTTGGAATACATACCTGCGCATACTTGATAATTCTTTTGACTTATCTT
TTCCTTGTTAGCTTTTACGAACACTAGAAGGTAGCATAAGAAGCAGGTGAATAATTGGAA
AGGTCGGCAAAACTGATATACTCTCATTGTGCCCTTACACTCTTAGTTTCTGTAAATTTA
CTGCCTTTTTACCAGCTGTTTCTTGAAATTACCGAGAAAATATTCTATTTCAATTTTTAA
CCTGCAAAACCTGAACAGAATAGTTGATCCTCTTGACTATTAGTTTGAGGCTAAGTTTTT
TTTTCCACTCTCCCTATTCCTACTCCTATATATATCTTGCTCTATCTTTTTCTTCAAGTT
CGTTTTTTCACACACTATTTAAAAGACCAAGCTTATGTGTGACGTGCACGGGTGCAATAT
CTAAATCGGGCAAAACAACTAAGCAGTAATTAAAGTACCACACTCTAGCCGAAAAGAGGT
ATACATGAAGGTTGAAGATTCGGAAGCAATTCCCAAATTATGTTCAACATTACGGATATT
ACAATGTTCAATGCGCATAATACACCATAGAAGAAAATTGGCACTACGTATATACTGTCC
ATTGTTCTTTTAAACACAAAATTGAAACGTCTGCGGTCTCTTGAGGATAAAACAATGTAC
ATTGAGTATAGTAACATGCTAAGCGTTAGCTTGTATCATCAAGACCGTCAAAGCAGGCAT
TTCATCAAATCTATAGGACCACTTAGCGGAGTCCTGGTGATTGTAGAAATAGCCTTCTAA
CGTATCAAGTGATAAATAATTTAAGTTTTCCGAATTTCAGTGATCTACTTACAATATTGC
TTATTAATCATTATAAAAAGAAGCGTATTTAGCGGACTAATTAGAATACATAAGGCATTC
TCAGCGTAATCTAAGCAAAAAAGCAAGAAATTGACTAACA
Chr coordinates Chr XI from 361828-361058
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