Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
NFU1
Systematic Name
YKL040C
Alias
NUB1
Strain
S288c
Description
Protein involved in Fe-S cluster transfer to mitochondrial clients; protects [4Fe-4S] clusters from damage due to oxidative stress; acts along with Bol3 at a late step in the transfer of [4Fe-4S] clusters from the ISA complex to client proteins; Fe-S loaded homodimer at steady state; similar to NifU, a bacterial protein required for Fe/S cluster maturation; ortholog of the human NFU1, mutations of which are associated with Multiple Mitochondria Dysfunctions Syndrome (MMDS1)
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>NFU1 YKL040C
ATGTTCAAATCAGTGGCTAAATTGGGGAAGTCTCCGATTTTTTACTTAAATTCTCAGAGA
TTAATTCATATTAAGACTTTAACAACTCCAAATGAAAATGCTTTAAAATTTCTCTCCACA
GATGGCGAGATGCTACAGACGCGTGGCTCCAAGAGTATAGTTATTAAGAACACTGATGAA
AACCTCATCAACCATTCCAAGTTAGCACAGCAAATTTTTTTGCAGTGTCCAGGAGTGGAG
TCTTTAATGATAGGTGATGATTTTCTCACTATTAATAAAGACAGAATGGTCCATTGGAAT
AGTATCAAGCCTGAAATTATAGATTTGTTAACCAAGCAACTTGCTTACGGTGAAGATGTT
ATATCCAAAGAATTCCATGCTGTCCAAGAAGAAGAAGGAGAAGGTGGCTACAAAATAAAT
ATGCCCAAATTTGAACTTACCGAAGAAGATGAAGAGGTCAGCGAATTGATTGAAGAGCTG
ATAGATACAAGAATAAGACCAGCCATCTTGGAGGACGGCGGTGATATCGATTACCGTGGG
TGGGATCCAAAGACTGGAACCGTTTATTTAAGATTACAAGGTGCATGTACCTCATGCTCT
TCTAGTGAAGTGACTTTGAAGTACGGTATTGAGTCCATGTTGAAGCACTATGTGGATGAA
GTGAAAGAAGTGATTCAGATCATGGATCCTGAGCAAGAAATAGCATTAAAGGAATTTGAT
AAGCTTGAAAAAAAGTTGGAATCGAGTAAAAATACAAGCCATGAAAAGTAA
Promoter Sequence
Download FASTA
>NFU1 YKL040C
CTCATCACTCAATCCACTTATTTTTTTAAGATTGAATGATATAAACGGGTCTATTTTGCC
CTTCCAATCTTCTTTGGAATACATACCTGCGCATACTTGATAATTCTTTTGACTTATCTT
TTCCTTGTTAGCTTTTACGAACACTAGAAGGTAGCATAAGAAGCAGGTGAATAATTGGAA
AGGTCGGCAAAACTGATATACTCTCATTGTGCCCTTACACTCTTAGTTTCTGTAAATTTA
CTGCCTTTTTACCAGCTGTTTCTTGAAATTACCGAGAAAATATTCTATTTCAATTTTTAA
CCTGCAAAACCTGAACAGAATAGTTGATCCTCTTGACTATTAGTTTGAGGCTAAGTTTTT
TTTTCCACTCTCCCTATTCCTACTCCTATATATATCTTGCTCTATCTTTTTCTTCAAGTT
CGTTTTTTCACACACTATTTAAAAGACCAAGCTTATGTGTGACGTGCACGGGTGCAATAT
CTAAATCGGGCAAAACAACTAAGCAGTAATTAAAGTACCACACTCTAGCCGAAAAGAGGT
ATACATGAAGGTTGAAGATTCGGAAGCAATTCCCAAATTATGTTCAACATTACGGATATT
ACAATGTTCAATGCGCATAATACACCATAGAAGAAAATTGGCACTACGTATATACTGTCC
ATTGTTCTTTTAAACACAAAATTGAAACGTCTGCGGTCTCTTGAGGATAAAACAATGTAC
ATTGAGTATAGTAACATGCTAAGCGTTAGCTTGTATCATCAAGACCGTCAAAGCAGGCAT
TTCATCAAATCTATAGGACCACTTAGCGGAGTCCTGGTGATTGTAGAAATAGCCTTCTAA
CGTATCAAGTGATAAATAATTTAAGTTTTCCGAATTTCAGTGATCTACTTACAATATTGC
TTATTAATCATTATAAAAAGAAGCGTATTTAGCGGACTAATTAGAATACATAAGGCATTC
TCAGCGTAATCTAAGCAAAAAAGCAAGAAATTGACTAACA
Chr coordinates
Chr XI from 361828-361058