Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name CUE2
Systematic Name YKL090W
Strain S288c
Description Ubiquitin-binding endonuclease involved in mRNA decay; recruited to stalled ribosomes to promote breakdown of transcript body of nuclear-transcribed mRNA with stalls in translation elongation; cleaves mRNA within A site of colliding ribosome; has two CUE domains that bind ubiquitin, which may facilitate intramolecular monoubiquitination
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>CUE2 YKL090W
ATATGTACTATGCCGACCTCTTTTCATGTAAACGCCTTGCAAATTCATACTTAATGATTA
CAAGAAAGTAATATGTAAATTTTAAGCTCAGGTTCAAGGTTTATAAGGGCCTTCGTCTCT
GATAGAAGAATCAAGTTGGTAAATCCAAATGGAAGTACGGGTCCCAATAGCAGGTTTGAT
TTTTGAAGGTGACTCGAGATATATCAGCTGCCGCCCCTGAATCAGCAGTAATTATAACTG
AAGAGAACGGACAATGTTTTACGTATAATTAAGGCACATAAATTCCATCTGGAGTGTTCT
GAAGTCGCTTACTTGGTGAGATATTGAGGTGTCATCAGATAGGACAATAGTAGGAGAAAG
GACCATCTGGAGGTTAATCACCTGTTGTCTTACTATCCGGTCCTCAGGGTCCATAAAAAA
ATACTTTCAACAAAATCTGGATGCATTGAAAAGGTTGTTTTCAAACAGTCTGCAGTTTGT
AATTCACCCACATGCCTTTTTTTGTATTCATATTAGCTTTTCTTGCATAATTAGGGACAT
ATAAATCGTGCACACATGGATATTTCTTCATAATATTATAGTCTGATTGATATTCAAAAT
TTGAAACATTTCCATAAATAATGGATAGGGGACAGCCAAAAAAAAACTGTTGTGCTCGAT
CCTGAATGGAAAAGACTGACACTATAAGGAGACTTATTCTAGATATCGTAGAACAAACAT
ATGTTACTTTAACGTCGCTGGACACTCACAGACAAGCCTCAGGGGAGACGTTTGAAACCG
TAGAGGAATACGTATGAAATATAAATCAACAAACATACGTACTGAATTATGTATCAGGAT
ATATTGCTTTCACAGTTTGGAAATTGCCTCTATCACCAAGATATTCACTGTTAAAAAAAA
AAATGCGAAAAAATTCAAATTTCAACAGCGATATTCGCCTTCAGTATATCAATATAAAGC
AATTATGACACCTCATTTATCGTGCATATAAGATCATGCA
Chr coordinates Chr XI from 271878-273209
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