Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
CUE2
Systematic Name
YKL090W
Strain
S288c
Description
Ubiquitin-binding endonuclease involved in mRNA decay; recruited to stalled ribosomes to promote breakdown of transcript body of nuclear-transcribed mRNA with stalls in translation elongation; cleaves mRNA within A site of colliding ribosome; has two CUE domains that bind ubiquitin, which may facilitate intramolecular monoubiquitination
External sources
Open in SGD
Open in KEGG
Gene Sequence
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Sequence hidden
Promoter Sequence
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>CUE2 YKL090W
ATATGTACTATGCCGACCTCTTTTCATGTAAACGCCTTGCAAATTCATACTTAATGATTA
CAAGAAAGTAATATGTAAATTTTAAGCTCAGGTTCAAGGTTTATAAGGGCCTTCGTCTCT
GATAGAAGAATCAAGTTGGTAAATCCAAATGGAAGTACGGGTCCCAATAGCAGGTTTGAT
TTTTGAAGGTGACTCGAGATATATCAGCTGCCGCCCCTGAATCAGCAGTAATTATAACTG
AAGAGAACGGACAATGTTTTACGTATAATTAAGGCACATAAATTCCATCTGGAGTGTTCT
GAAGTCGCTTACTTGGTGAGATATTGAGGTGTCATCAGATAGGACAATAGTAGGAGAAAG
GACCATCTGGAGGTTAATCACCTGTTGTCTTACTATCCGGTCCTCAGGGTCCATAAAAAA
ATACTTTCAACAAAATCTGGATGCATTGAAAAGGTTGTTTTCAAACAGTCTGCAGTTTGT
AATTCACCCACATGCCTTTTTTTGTATTCATATTAGCTTTTCTTGCATAATTAGGGACAT
ATAAATCGTGCACACATGGATATTTCTTCATAATATTATAGTCTGATTGATATTCAAAAT
TTGAAACATTTCCATAAATAATGGATAGGGGACAGCCAAAAAAAAACTGTTGTGCTCGAT
CCTGAATGGAAAAGACTGACACTATAAGGAGACTTATTCTAGATATCGTAGAACAAACAT
ATGTTACTTTAACGTCGCTGGACACTCACAGACAAGCCTCAGGGGAGACGTTTGAAACCG
TAGAGGAATACGTATGAAATATAAATCAACAAACATACGTACTGAATTATGTATCAGGAT
ATATTGCTTTCACAGTTTGGAAATTGCCTCTATCACCAAGATATTCACTGTTAAAAAAAA
AAATGCGAAAAAATTCAAATTTCAACAGCGATATTCGCCTTCAGTATATCAATATAAAGC
AATTATGACACCTCATTTATCGTGCATATAAGATCATGCA
Chr coordinates
Chr XI from 271878-273209