Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
SLD2
Systematic Name
YKL108W
Alias
DRC1
Strain
S288c
Description
Single-stranded DNA origin-binding and annealing protein; required for initiation of DNA replication; phosphorylated in S phase by cyclin-dependent kinases (Cdks), promoting origin binding, DNA replication and Dpb11p complex formation; component of the preloading complex; binds the Mcm2-7p complex to prevent inappropriate Mcm2-7p interaction with the GINS complex in G1; required for S phase checkpoint; relative distribution to the nucleus increases upon DNA replication stress
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>SLD2 YKL108W
ATGTACTCATTTGAACTGGACAAATTGAAAATTGAGCTGAAAACATGGGAGCATGATTTC
ATTGATAAAAATAAAAGGGAACCCACAAGGGATGACATCAAGAGCCTGCGGACTGTTCGG
CAGATGTATAAACAATATTCCACACTGAAGAAGAAACAATCTTTGCAACGACAAAAAGTT
GACACTCAAGAGTCGGTTGAACTCCCGGCACATAAAAAAGACCACGACGAAGTCGTAGAG
ATAGGCCCTACTCCCCAAGTTTACGGTAAGGCGATTAGTATCTTTGACATGAATTTGTCG
CCTATAAAGCCTATATACATGACATTCACAAATAATATTGATGTTAACAATGATAACTCC
AAGACAATTTCTAATGAATCTTCTCCACGAAAAACTATTCTCCTAAAATCGTCGCCTGCA
GATCGTACGTTAGTGGCGGAACCAATATCCAGTGTGAAACGCCAATTAAACTTTCAAATG
CTAAACGCTTCTTCTACACGTACTCCGACTTCATCACCATGCAAGAATCGCAATGGGAAG
TTGGTAGAAATCAAGAAATGTAGTCCAACTATTAATCCTCCACTAGAATCTGGCAAACCA
TCGGGGTATTATGGACCTAATTCCCCGCTAAAATTGGATGAAGAAAACATTCACCTAAAC
ATCTCACTTAATTCAAGCACTAAACGCCGGCTTCAAATAGCATATCCATCTTTACAGAAG
ACTCCCTCAAAGGATCAAGCGGATATTTCAACTTCATTTAGTCCGTCTCCACTCATTAGA
AGACCACTGACGAAATCCCTGATAGAATTGGCCAGGGAACATACTGAAATTGTAAAAGAA
TTTGGTGTCTTACAGGAAGAAGATATTGAAGAGGAAGAGGAAGGAGAAGAAGGCGAGAAT
GGTTACGATGAGAAAAACCACGAAGACGACTTTGGGCTAGAAGATGAACTAATTAGACCA
AAAGTTGTGAAGGACATATTTCAAGAGGATGATGATAATGATGATAGCCAAGCAAGGGAA
GATACCTTCATAAGAAAGAGACCCAAAAGAAGAAAGGTTATCAGAAGATTACGAGACAAT
GATCCAGAAACCGAGACCGCAGGTTTTGAGAGAGATGTCCATAAGGAGCTGGTGAAACTC
AAAAGAAGGAAAGTGGCAGAATTTTTGGGATCCACCTCACAAATCTCTGATACTGAATTT
GAACATGATCCGGAGGCAAGCAGCGGCGTTGTAAGCTCAGAGCAAAAGCCTACGGCTAAG
CGAAAGGGTAGAAAGAAGTATAATCTAGTGAGCAATAACTTCAGAAGACTAAAACTGCCA
AAGAAAAACCGATTCTCTAATGGACGATGGGGAAGAAGGTGA
Promoter Sequence
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>SLD2 YKL108W
ACAAGAAGATTCATCACGTGCTTTGAAAAAAAATACTAATTCTGAGAAGGCGAACATCCA
AGCAAAGAACGATGAAACCTATCTGTTTCTTCAGGATCAGGATGAAAGCGCTGATTCGCA
TCACCATGACGAGTTAGGTTCAGAAATCACTTTGGCTGACAATAAGTTTTCTTATTTGCC
CCCAACTCTAGAAGAGTTGATGGAAGAGCAGGACTGTAACAATGGCAGATCTTTTAAAAA
TTTCATGTTTTCCAACGATACCGGTATTGACGGTAGTGCCGGTACTGATGACGACTACAC
CAAAGTTCTGAAATCCAAAAAAATTTCTACGTCGAAGTCGAACGCTAACCTTTATGACTT
AAACGATAACAACAATGATGCAACTGCCACCAATGAACTTGATCAAAGCAGTTTCATCGA
CGACCTTGACGAAGATGTCGATTTTTTAAAGGTACAAGTATTTTGAAATAGGCATGTTGC
AATAAAACGAAAACAACTAAAAATCACGAAAACAAAATGATATTATACAATAAAAAATTC
TTATTATGGGTAATGATAGTATTCTTCGCCTGCTTAGGCGTCCTTTTCCTTCAACAACAA
AAATTCCAAAAAAAAAAAGTAAAAAAACAAAACTTTGATTGTTTTTTAATGATGTTAATG
ATTTTTTTTTTCTTTCTTTATCATAAAAAAAAAGTTAAAATGAAAAACAAATATGGGTCT
GGAAGGCCATTATTTTTTTTTTATTTATATACCGTTTCTGGTACTTAGTTATTTATTCTC
ATACATACACTATATTCAAATTACCTAAGAGCATTTTCACATATCCGTTTACTTTCATTT
TTTTTTTTTTTGCTTCCTTTTTACATATCTTCCGTATATCACATCACGTTTACGCGTATG
GTGAAACACGTCAAGAGAAAAATGATAAAATCAAATTTTGATTTACATCAGGCTCCACAG
GACAGGGAAATCTATCTAGTGAGGCGATAACTGTAGTTCG
Chr coordinates
Chr XI from 234426-235787