Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
YPK1
Systematic Name
YKL126W
Alias
SLI2
Strain
S288c
Description
S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant and the inviability of a ypk1 ypk2 double mutant
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>YPK1 YKL126W
ATGTATTCTTGGAAGTCAAAGTTTAAGTTTGGAAAATCTAAAGAAGAAAAAGAAGCCAAA
CATAGTGGGTTTTTTCACTCCTCTAAAAAGGAAGAACAGCAGAATAATCAAGCAACTGCG
GGGGAACATGATGCTTCAATTACTCGTTCATCTTTAGACAGGAAGGGCACGATAAATCCA
TCAAATTCATCAGTGGTCCCGGTTCGTGTTTCATACGATGCATCCTCATCGACCTCTACT
GTACGAGATTCAAATGGTGGTAATTCAGAAAACACGAACTCATCTCAAAATTTAGATGAA
ACAGCAAATATTGGTTCTACAGGGACACCCAATGATGCCACCTCAAGTTCAGGAATGATG
ACTATCAAAGTATATAATGGTGATGACTTTATTTTACCTTTTCCGATTACCTCAAGCGAG
CAAATATTGAATAAACTATTGGCCTCGGGTGTTCCACCGCCACATAAGGAGATTAGTAAA
GAAGTAGATGCTTTAATTGCACAACTGTCCCGTGTTCAAATAAAGAACCAAGGTCCAGCT
GATGAAGATTTGATCTCTAGCGAGTCAGCAGCAAAGTTCATCCCATCTACTATCATGTTA
CCAGGGTCTTCGACCTTAAATCCCTTACTATATTTCACCATTGAATTTGATAATACAGTT
GCAACTATTGAAGCAGAGTATGGTACGATCGCTAAACCTGGTTTCAATAAGATATCTACC
TTTGATGTGACAAGGAAATTACCTTATTTAAAGATTGATGTATTTGCAAGAATTCCGTCC
ATTCTTTTGCCCTCGAAGACATGGCAACAGGAGATGGGTTTGCAAGACGAGAAGCTACAG
ACCATTTTTGATAAAATAAATTCCAATCAAGATATACATTTAGATTCTTTCCATTTGCCC
ATCAACTTAAGTTTTGACTCTGCAGCTAGTATTAGACTATATAATCACCACTGGATCACA
TTGGATAATGGCTTGGGTAAGATCAATATTAGTATTGATTATAAACCTTCCAGAAATAAA
CCTTTGTCCATCGATGATTTCGATCTTTTGAAAGTTATCGGTAAGGGTTCGTTTGGTAAA
GTGATGCAAGTCAGAAAGAAAGATACACAAAAAGTATACGCTTTGAAGGCAATCAGAAAA
TCATACATTGTCTCTAAATCCGAAGTCACGCATACTTTGGCAGAAAGAACCGTTCTAGCA
CGTGTTGATTGTCCATTTATTGTACCTTTGAAGTTTTCTTTCCAATCACCGGAAAAATTA
TACTTTGTTTTAGCGTTTATCAATGGTGGTGAGTTGTTTTATCATCTACAAAAGGAAGGA
AGGTTTGATTTATCACGTGCCAGATTTTATACCGCAGAATTGTTATGTGCGCTAGACAAC
TTGCATAAACTAGATGTTGTCTATCGTGATTTGAAACCAGAGAATATTTTATTGGATTAT
CAAGGCCACATTGCCCTTTGTGATTTCGGGCTATGCAAATTGAATATGAAGGATGATGAT
AAGACAGATACTTTTTGTGGGACCCCAGAATACTTGGCACCAGAACTATTGCTAGGTTTA
GGCTATACAAAGGCAGTAGATTGGTGGACATTGGGAGTCTTGTTATACGAGATGCTCACA
GGTCTTCCTCCTTATTATGATGAAGATGTTCCAAAAATGTATAAGAAGATTCTACAGGAG
CCACTAGTTTTCCCAGATGGATTTGATAGAGATGCAAAGGATCTATTGATTGGATTATTG
AGCCGTGATCCGACAAGAAGATTGGGCTACAATGGTGCCGACGAAATTCGGAACCATCCT
TTTTTCAGCCAATTATCATGGAAGCGCCTGTTGATGAAGGGTTATATTCCACCATATAAA
CCAGCTGTTAGTAATTCCATGGATACTAGTAATTTCGATGAGGAATTCACTAGGGAGAAG
CCAATTGATAGTGTGGTAGATGAATACTTGAGTGAAAGTGTTCAAAAGCAATTTGGTGGC
TGGACATACGTTGGAAATGAACAGCTAGGTAGCTCAATGGTGCAAGGTAGAAGCATTAGA
TAG
Promoter Sequence
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>YPK1 YKL126W
CAGAGAAAAGGACGGTCTATGGGCCATTATTGCTTGGTTAAATATCTTGGCTATCTACCA
TAGGCGTAACCCTGAAAAGGAAGCTTCGATCAAAACTATTCAGGACGAATTTTGGAACGA
GTATGGCCGTACTTTCTTCACAAGATACGATTACGAACATATCGAATGCGAGCAGGCCGA
AAAAGTTGTAGCTCTTTTGAGTGAATTTGTATCAAGGCCAAACGTTTGTGGCTCCCACTT
CCCAGCTGATGAGTCTTTAACCGTTATCGATTGTGGTGATTTTTCGTATAGAGATCTAGA
TGGCTCCATCTCTGAAAATCAAGGCCTTTTCGTAAAGTTTTCGAATGGGACTAAATTTGT
TTTGAGGTTATCCGGCACAGGCAGTTCTGGTGCAACAATAAGATTATACGTAGAAAAGTA
TACTGATAAAAAGGAGAACTATGGCCAAACAGCTGACGTCTTCTTGAAACCCGTCATCAA
CTCCATTGTAAAATTCTTAAGATTTAAAGAAATTTTAGGAACAGACGAACCAACAGTCCG
CACATAGAATTATTGGTCTTGAACAAGCACTAATTTTCCAAAGATGTTTTAACTGATCTT
AATTTATATGTAGAGGATATATGTAGTATATCTATTTTTTGCTGATTGACTTATCAATTA
GCTTCATAATACAACATTGTTTTTGTTTTTCGTTACTCGCGACTTTCTTCGCGGCAGAGC
CGCGCTACAGGAAAACAAGATCAAAACATGCCCCTATTGGAAGGCTTAAAAAATGCTTAT
CCCGAACGAGCCAACGGTAATCAACACTATCGTCATACCAACAACAGTTGAGTTATTTTT
CGCTCCCATACTTTTTAGAATTGGTTTGTTTGTGTTTGGTTAAATTTCAAAGCCTTTATA
TTCTTTGATATAGATTACTCTACAATTTCTTTGTATACAGCGGGAAATTGACACTTCAAA
GTTCCTCTCATATCAACAAACATTAATACAGTTCCTGAAA
Chr coordinates
Chr XI from 205707-207749