Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name CTK1
Systematic Name YKL139W
Strain S288c
Description Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3' end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>CTK1 YKL139W
TATGAACACCTGGATTTGATTTGGGGCAAAGATGCCGATACCTTGGTCATTGCTAAAGTC
TTGAGGTTTATTGAATTTTTTAACCCTGGTAATGTTTCAGTGAAGACTAACCAGTTACTA
CCATCAGCAAGTCTGGTTGAGGAATTACCAAGCACGACATGGAAGACAACTCATCCAACG
CATGGTCTCAGTTATAGAACTCACTCGGCAGACCGTTCTCCGTTGTCTGTACAAGCTGAT
GAAGCGGATGAGGTCCACAATGCTGACAATTCAAGGTTCTTAAGACGAGTGTTTTCTACT
AGTGCCATAGACGAGGACAACGAAAATGAGCACCAGGATGATACAGAAGATCAAATCCAT
AAGGAGCAGCAAAGACGGTTAAGTGCCTATCTGGAATCATCCAAAGATTTACGACAACTA
GATGCCAACTCTTCGACAACTGCGCTGGATGCTCTAAATAAAGAATGAAAAGAATGCGAG
AGAAACCCTATTAAACTATTTTTTGTCTAGGATAATAATATTAGCGCTAATCTAAAAATC
GATGAACTAAAGAAAGAATATACGTACGTTTTATACACAATAAATGGATTTCATAAGAAG
TCCTTAATATCCTCATGCTTGTGGATACTGGAAATTAGTAAAGTAATTAACTTCCTTTTA
GCATTATTCTTATTTGGCTTAAAAAGGTCACGTGAAGCTCTATTTTTTTCGTTTTTTTTT
TTCACTGATGGAAGAGAAAAACCTCTACATAATAAGGTAACTTTACATATTGATTGCCAA
TGAGATGTTAAAAAATGGACGGTTCAGACAGTAAAATACATTTAGAAAAAAAGAGAAGGT
CTTATCAGTGTATTTATTCACTGTGCATATTAGCTTTTTTTGGACTTTTTTTGTTCCATT
AGTACTTTTAAAAAACCTATTTGTAAATAAAACTAATTCTAGCACTATTCTTTGCACTAG
AATAACACAGGGACCATACAGCATAAATTATTTGGTAACA
Chr coordinates Chr XI from 182958-184544
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