Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
SDH1 Systematic Name
YKL148C Alias
SDHA Strain
S288c Description
Flavoprotein subunit of succinate dehydrogenase; couples the oxidation of succinate to the transfer of electrons to ubiquinone as part of the TCA cycle and the mitochondrial respiratory chain; FAD binding to Sdh1p is required for the assembly of the succinate dehydrogenase subunits; mutations in human ortholog SDHA are associated with Leigh syndrome and predisposition to several cancers External sources
Open in SGD
Open in KEGG
Gene Sequence
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>SDH1 YKL148C
ATGCTATCGCTAAAAAAATCAGCGCTCTCCAAGTTGACTTTGCTCAGAAACACAAGAACA
TTTACATCGTCAGCTTTGGTGCGCCAAACGCAGGGCTCTGTAAACGGTTCCGCGTCCAGA
TCTGCAGACGGGAAGTACCACATAATAGATCACGAGTATGACTGTGTGGTAATCGGTGCC
GGTGGTGCCGGCCTTAGAGCGGCCTTTGGTCTTGCCGAGGCGGGCTACAAGACTGCTTGT
ATATCCAAGCTTTTCCCCACCAGATCCCACACTGTTGCTGCTCAGGGTGGTATCAATGCC
GCTCTGGGAAATATGCACAAGGATAACTGGAAATGGCATATGTACGATACTGTGAAAGGA
TCTGATTGGCTAGGTGACCAGGACTCCATCCATTACATGACCAGGGAAGCGCCCAAATCG
ATCATTGAACTGGAACACTATGGTGTTCCTTTTTCAAGAACTGAAAACGGTAAGATCTAC
CAAAGAGCCTTTGGTGGTCAGACCAAGGAGTACGGTAAGGGTGCTCAGGCCTATAGAACA
TGCGCTGTCGCAGACAGGACAGGACATGCTCTTTTACACACGCTTTATGGCCAAGCTTTA
AGACATGACACACATTTCTTTATTGAGTACTTTGCCCTCGATCTGTTGACCCATAATGGC
GAGGTCGTTGGTGTCATCGCTTATAATCAGGAAGACGGTACCATCCACAGATTCAGAGCA
CACAAGACCATTATTGCCACTGGTGGCTATGGTAGAGCATACTTCTCTTGTACCTCTGCT
CACACATGTACGGGTGACGGTAATGCCATGGTTTCGCGTGCTGGTTTCCCCTTGCAAGAT
TTAGAGTTTGTTCAATTCCATCCTTCAGGTATATATGGGTCTGGTTGCTTAATCACTGAA
GGTGCTCGTGGTGAAGGTGGTTTTTTGGTTAATTCTGAAGGTGAAAGATTCATGGAACGT
TACGCTCCTACGGCCAAGGATCTAGCTTGTAGAGATGTCGTTTCCAGAGCAATCACCATG
GAGATCAGAGAAGGCAGAGGTGTTGGTAAGAAAAAGGACCACATGTACTTACAATTGAGC
CATCTACCTCCGGAAGTTCTAAAGGAAAGATTGCCAGGTATCTCTGAAACAGCAGCCATT
TTTGCTGGTGTAGACGTCACCAAGGAACCTATTCCCATTATTCCTACCGTCCACTATAAC
ATGGGTGGTATTCCCACGAAGTGGAATGGTGAGGCATTAACCATTGATGAAGAAACTGGC
GAAGACAAGGTTATTCCCGGTTTAATGGCTTGTGGTGAAGCCGCTTGTGTTTCTGTCCAT
GGTGCCAATAGATTAGGTGCCAATTCCTTGTTGGATCTTGTTGTCTTTGGTCGTGCTGTT
GCCCATACGGTTGCTGACACTTTACAGCCTGGGTTGCCACACAAACCACTACCTTCTGAT
TTGGGTAAAGAATCCATCGCAAACTTGGATAAACTAAGAAATGCTAATGGTTCAAGATCT
ACGGCAGAAATTAGAATGAATATGAAACAAACTATGCAAAAGGATGTTTCCGTCTTTAGA
ACACAATCATCTTTAGATGAAGGTGTTCGGAACATTACTGCAGTAGAGAAGACCTTTGAT
GATGTGAAGACGACCGATAGATCAATGATCTGGAATTCTGACTTGGTTGAAACTCTGGAG
CTACAGAACTTATTAACCTGTGCCTCCCAAACAGCTGTTTCCGCTGCTAATAGAAAGGAA
TCCCGTGGTGCTCATGCAAGAGAGGATTATCCAAATAGAGATGACGAACATTGGATGAAG
CATACATTATCCTGGCAAAAGGACGTCGCTGCCCCAGTGACTTTGAAATACAGAAGGGTT
ATCGATCACACTTTGGACGAAAAGGAATGTCCTTCCGTACCTCCAACTGTAAGAGCCTAC
TAA Promoter Sequence
Download FASTA
>SDH1 YKL148C
CTTATCAAGTGGCGTGCCACGGCATCTACCACATGTGGCTCAGGGTTATTTATGCTCACT
TCAAGCGTGCCATTGTTACAGGAAGTGTGCGACGCGTCGGGTACGCTAGCATGCACCGCT
TCATTGTTCACAAGCAGCGGCGGCTTTTTTAGCAAACCACCTGTAGTTCCACTAGATTTT
CTACTTCTGCTTCTACTTCTACTATTACCGTTGCTATTGCCACCGTTGCCGTCCGTTAAA
GGTGAGCCAGACGCATGCGAGATTCCTGTACTGCCTCCGTTGTTATTTTTTTTGTTGTTG
TTGCTCTGCGTTCTTCCAGAGCCACTTGAAACCTCTTTTCCATTCATATCCGCGATGCAA
TCCCTTATACGCTTCTTAATAAACTTTGCTTCCCACTCTTTCACTACTGACCATCGATCC
TTCTTATTTCATAGCCTCACGAGCACAAATGATAATACGAGAAAAAGGCCCGACCGGGTA
ACCAACCCTTTTACTATCTCTCGCTCTACCTTTAGTAATAATGTCGTCTATATAAGGATT
TACTCATACAGTAGTCCAAAATATACCTTTCCGTGCTAAAAGTAGCTCCCAAAAGTAGCG
GAGGTGAGGATCATCCTCTATTGCCAGGTACCAAGCTCGCTGGAAAGTCGTTATGGAGTC
ACGGCTTTGAGGGCGGGGGTGGACCAATCACAGCGCAGAACGCGGCGCCGAGCAAGCGCT
GGACCAAGGGATCCGGGCCTCTTCTATTGGTTGTTTGTTTGCTCAAACCCGTTATATATT
CAGGCATCCTCGACTCTAACCTTTTGCCACGTCGAGGCGGCTTGAAGCTTAAATAGCACT
AATAAACTAGTAGACACATTATAACTAACCAGTAGTATACTTTGCACTTTCGATATTCTT
TTCACTAATCTCCTCCCCAACCCCTTATTGAAGATAAAAAGAAAGAAAGAAAGAAAGAAA
AAAATCCAATTTCATAGTACGAAGAAGAACGAGAATAAAG
Chr coordinates
Chr XI from 171129-169207
