Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
NNR2
Systematic Name
YKL151C
Strain
S288c
Description
Widely-conserved NADHX dehydratase; converts (S)-NADHX to NADH in ATP-dependent manner; YKL151C promoter contains STREs (stress response elements) and expression is induced by heat shock or methyl methanesulfonate; downstream intergenic region drives antisense expression and mediates coordinated regulation of YKL151C and GPM1 phosphoglycerate mutase; protein abundance increases in response to DNA replication stress; homolog of Carkd in mammals and C-terminus of YjeF in E.coli
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>NNR2 YKL151C
ATGTTAGCAGAATTGTCTCATAGAGAATTGATAAAGTTGGCGCAGAAAAGATGTATACCA
CCTTTATTGCCAAAGTTTCATAAGGGACAGTCTGGTGGGAGAGTTTGCATTATTGGAGGA
TGCGAAGATTATACAGGGGCACCGTATTTCAGCGCCAATGCTACAGCCTTGATGGGCTGT
GATTTGACACATGTCATCTGCGAATACAACGCTGGTACGGTCATTAAATCGTACACCCCA
AACCTAATGGTTCATCCATACCTTCGTATGAGTAACACCAAATTAGACGTTGATATGGAC
GAACAAAGGAAGAAAATCAATTCCTTATTGGATAGAATCCACGTTGTGGTAATTGGACCC
GGCTTGGGTAGGGACCCCCTAATGTTAAAATCCATTAAGGATATCATAAGATATATACTT
GAAAAACATGAGGGCAAGATCCCGTTAGTAATTGATGCTGATGGACTGTTCTTAGTAACT
CAAGATAGCGAAGTCAAAGAAATGCTGAAAAGCTACCCCAAAGGTAGAGTGATCTTGACG
CCCAATGTGGTAGAATTCAAAAGACTATGTGATGCCATAGGCAAGAAGGGAGACTCTCAC
TCCGAGATGGGCAGCTTGATCGCCCAGGAATTGAATTGTATTGTGGTGGAGAAAGGTCAG
TCAGATAAGATATTCTCACCCGATAGTGAAAAAGACATGTTGACGAACAGCGAAGAGGGC
AGCAACAAGAGGGTAGGAGGCCAAGGTGATACTTTGACAGGAGCTATATCATGCATGCTT
GCATTTAGTCGTGCAATGTATGACTTTAAGATTTGTGAGCAGGAAGAAAAGGGAGAATCT
TCTAACGATAAACCCTTGAAAAACTGGGTAGACTACGCTATGTTGAGTTGCTACGCAGGC
TGCACAATTACACGAGAATGCTCCCGCCTAGGATTTAAGGCTAAGGGACGTGCAATGCAG
ACGACAGATCTAAATGACCGTGTCGGTGAAGTGTTCGCCAAACTTTTCGGTTAA
Promoter Sequence
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>NNR2 YKL151C
TTTACCACCTTCATAATGCTTGACGACCAGCTGGAAGTGACCCTTCTGGGAAAGATCACT
CACAGGAGTGTATGGTCTCACCACATTGGATCCCTTTGGTGTGACAAATTTAGCAAACAG
AGCAGATGCTAGGACCAACCCCATTTCTGAGTCTTCGGTAGGCAGCTTAAAAGTAAACCT
TCTGGTGTCGTGGGATTCCTCCTCTATTTTAGATATTGGCAAGTCGATCCATTTGTCATC
ACCTTTGAACACTTTATTAGATTCATTGAAGACAAAGGAATGTTGGTTACGGTTTGCAAA
ATAGAATGCGGTAGCAGCTGCTATAGCAACTGTACCTAGAGCAATCGGTAATGCTTTTGA
GTGAGATCTGGATAATCTGGAAAACATGTTTTTGACTTGGAATATTATTTTAACCTATAT
ACGTTATACTATTGTTAGTTTGGCTGCTTCAAAACGTTAGTATTGAGGGAAAAGGTAAGA
GTACTTAACACAAGCGGGCATTGCGAGCAAACTGCATTCTTATATACGTACCTCTCTCGA
CAAGACACCAATCAAGGGCCCTTATTTCTCTTCTTTTTTCAAACGGAGAAACACTCCGAG
CGATAGTTCCTACGCTTGTTTGGTCTTAGACCTTTGAAGTTTGAATTGTCAGGGGTAACA
AGTTCCTTATACGATATAGGCGTCATAATGAGGGGGATAGTTTAGCATTGCGTGGAGGGA
TACTGAAGGTCATCGCAAATGAACCTAATTCATTCACCTATTGTTACCAGCTTGCATACT
AGAAATGGACTCTTATGATCGTCAAAAGGAGCACACACCCACACACGACTCCTTTGCGCT
GTAAAGGGCAGAATAGGGAGTGATGTGATGTGATGCGATGTGATGGGTCTTGCAACGTGA
TCTAGTAGATATATATGTAAAGGTGTAAATAGGTATATAGGCGTCGGTGAAATTTTATTA
GCAACACCAGTTCAATACGATCACTACCGTATCACTGGAA
Chr coordinates
Chr XI from 165930-164917