Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
SPE1
Systematic Name
YKL184W
Alias
ORD1, SPE10
Strain
S288c
Description
Ornithine decarboxylase; catalyzes the first step in polyamine biosynthesis; degraded in a proteasome-dependent manner in the presence of excess polyamines; deletion decreases lifespan, and increases necrotic cell death and ROS generation
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>SPE1 YKL184W
ATGTCTAGTACTCAAGTAGGAAATGCTCTATCTAGTTCCACTACTACTTTAGTGGACTTG
TCTAATTCTACGGTTACCCAAAAGAAGCAATATTATAAAGATGGCGAGACGCTGCACAAT
CTTTTGCTTGAACTAAAGAATAACCAAGATTTGGAACTTTTACCGCATGAACAAGCGCAT
CCTAAAATATTTCAAGCGCTCAAGGCTCGTATTGGTAGAATTAATAATGAAACGTGCGAC
CCCGGTGAGGAGAACTCGTTTTTCATATGCGATTTGGGAGAAGTCAAGAGATTATTCAAC
AACTGGGTGAAGGAGCTTCCTAGAATTAAGCCATTTTATGCCGTCAAATGTAATCCTGAT
ACCAAGGTTTTGTCATTATTAGCAGAGTTGGGCGTTAATTTCGATTGCGCTTCCAAAGTG
GAAATTGACAGAGTATTATCGATGAACATCTCGCCGGATAGAATTGTTTACGCTAATCCT
TGTAAAGTAGCATCTTTCATTAGATATGCAGCTTCAAAAAATGTAATGAAGTCTACTTTT
GACAATGTAGAAGAATTGCATAAAATCAAAAAGTTTCATCCTGAGTCTCAGTTGTTATTA
AGAATCGCTACCGATGACTCTACCGCTCAATGTCGACTTTCCACCAAATATGGCTGTGAA
ATGGAAAACGTAGACGTTTTATTAAAGGCTATAAAGGAACTAGGTTTAAACCTGGCTGGT
GTTTCTTTCCACGTCGGTTCAGGCGCTTCTGATTTTACAAGCTTATACAAAGCCGTTAGA
GATGCAAGAACGGTATTTGACAAAGCTGCTAACGAATACGGGTTGCCCCCTTTGAAGATT
TTGGATGTAGGTGGTGGATTTCAATTTGAATCCTTCAAAGAATCAACTGCTGTTTTGCGT
CTAGCGCTAGAGGAATTTTTCCCTGTAGGTTGTGGTGTTGATATAATTGCAGAGCCTGGC
AGATACTTTGTAGCTACAGCGTTCACTTTGGCATCTCATGTGATTGCGAAGAGAAAACTG
TCTGAGAATGAAGCAATGATTTACACTAACGATGGTGTATACGGGAACATGAATTGTATT
TTATTCGATCATCAAGAGCCCCATCCAAGAACCCTTTATCATAATTTGGAATTTCATTAC
GACGATTTTGAATCCACTACTGCGGTCCTCGACTCTATCAACAAAACAAGATCTGAGTAT
CCATATAAAGTTTCCATCTGGGGACCCACATGTGATGGTTTGGATTGTATTGCCAAAGAG
TATTACATGAAGCATGATGTTATAGTCGGTGATTGGTTTTATTTTCCTGCCCTGGGTGCC
TACACATCATCGGCGGCTACTCAATTCAACGGCTTTGAGCAGACTGCGGATATAGTATAC
ATAGACTCTGAACTCGATTGA
Promoter Sequence
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>SPE1 YKL184W
CTGCATCTTCATCTCCATCTCCCTCCACACCGACGAAAAGTGGCAAGATGAGATCAAGAT
CATCCTCACCTGTGCGTCCCAAGGCATACACTCCAAGCCCAAGGTCACCCAATTATCATA
GATTTGCTCTCGACTCTCCCCCTCAAAGCCCTCGAAGATCATCAAATTCAAGCATAACGA
AAAAGGGAAGTAGAAGGTCCAGTGGCTCATCACCCACTCGTCACACCACAAGAGTGTGCG
TGTCGTGTCATTCGAGTGATTCGCCCTGTTGGAGGCCATCGTGGTCGCCAAGAAAGCAAG
ATCAGCTATGTAACTCTTGTGGTCTTCGATATAAAAAAACACATACAAGATGTTTGAACG
ATTTATGTCGTAAGATCCCCACAAAGGGTGAAATAAACATTATGAAATCCAATGGAATAG
ACAAAGAATTCGTCCCCGAACGCAACTGCGAAATTGAAGGGTACCGTTGCTTATTTTGTA
ATTACATAACTGAGACAGTAGAGAATTGATACATGGATAACTGAATCTCTTTCAACTAAT
AAGAGACATTATCACGAAACAATTGTACATTTCTCTCCTTGTCTGTGCTAAATAAACTAC
AAATAAAAATTCATTTTCTTTCATTTTCATTCGACACGCCGCGGCATCTTCGTTTTCTTC
ACCGATTAATTTTAATCTGCGCCGTGCAGATATTTTCGCCCATTTCGAAGTGAAATCATT
CTAATAACTTCTCCTGCGCAATAGATTGGTCATCCTGATTTTTATTCTGAAATCGAAAAT
GAAAAGCATTTATTGCACTGAAATAGCGGAACCTGCTTCTAATAAGCTTAAAATTCAATC
ATAATAGTGTAGTTAATAGAAAGGACAGAAGAACTTTTCGTTCCTTGGTTTATCATCCAG
GTTTCAGCACGGCTTTTGTTTCAAGTTTAAGTAGGTAAGATTTTTTGATTGTTCTACAAC
TTTTTCATAGTAATCAAAACCTTTGAATTTCAAACTTACT
Chr coordinates
Chr XI from 96757-98157