Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
MIA40
Systematic Name
YKL195W
Alias
FMP15, TIM40
Strain
S288c
Description
Import and assembly protein in mitochondrial intermembrane space; component of MIA pathway which mediates import and oxidative folding of substrates including small proteins containing twin cysteine motifs; acts in concert with Erv1p, which oxidizes the cysteine residues of Mia40p to comprise a disulfide relay system that catalyzes import; also mediates folding of Atp23p via a chaperone-like activity; forms a dimer that binds iron-sulfur cluster in vitro
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>MIA40 YKL195W
ATGCTTCGCAACTTAGTCGTCAGGAATGCGTGCAGAAACAGGCCGTCAATTCAAGTGGCA
AGGGGGTTATGCCGACACCAAACAAGACGTCTCATGGCGTCCTCCCCTCAGTTCGGTAGG
AACTCCAATCAGGAAAAAACAGCGGGCTTTATAATGGGGATTCTTTCTATGGCTGGTGCT
TTATATTTTATTGCTCCTAATAGGAAGCCTCTTTTCGCCTCAAGGAAGGTAGAATCCGAT
AAAACCGCAGAGGAAGAGCTTTCCAGTGGTGGTGAGCAATCACCAGAAAATGAAGATGAC
AACAACAGCAAAAGCGATGAAAATGGAGATGACAACGACAGCAAAAACGATGAAACTGAA
GCTGGCCCTCAATTAGGGGGTGATAAAATTGGTGCTTCAAAAGTAGCTGAAGATGGTGAA
TTGGTTGTTCTAGCAGAAGAAGACAACAAGTCTTCCGAAGATAAAGATACTGATGAATCA
AAGGTATCAACCAAAGATGATGAGCAATCCAATGAAGACAATGCCACCGCTAACAATCAA
AAGGATGAAAACATAAGTTCTGAGAACTCGGAAGAAAATACTAGTGACAAAACACTAGAC
AACAATGCTGGATCTTCTGAAAAAAAAGATCCAGAACATTCAGATGATGAAAAATCGCAA
CAGGGACAATCTGATGACAAGACAACTACTGAAGATAATAATGGAGAAGAAGAATCCTCA
AAAAAAACTGTAAGTGACTCGGAAAATTCAGCTAAGCAATCTGAATCTAGCGATGAAGAG
AAAGAAGAACTAAGAAAACAAGAGGAAAAGCAAATGGGTCCTACTGAAGAAGAGGTTCAA
CACGAAGGTGCTTATAACCCAGACACTGGTGAGATAAATTGGGACTGTCCTTGCTTGGGA
GGTATGGCCCATGGACCCTGTGGTGAAGAGTTCAAATCTGCATTTTCTTGCTTCGTCTAT
TCTGAAGCTGAACCAAAAGGTATCGACTGTGTTGAAAAGTTTCAACATATGCAAGACTGT
TTCAGAAAATACCCCGAGCATTATGCAGAACAACTAAAGGAAACATCTGATGATGAGGAA
CCTCAAGACAAAGTAAAGGTCAACACAATAGAATCAGCGCCAAATGTTTCAAGCGCAAAG
GAAAATGCTGCGAAAAAAGCAGAGCAATCAGATGTGAAAAAAGAACCATTGAATGAGGAA
TCCAAACCTTAA
Promoter Sequence
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>MIA40 YKL195W
AATTAATTTGATTTAAAAGATTTTTGTTTCCCTTGCTGCTGTCATTGGCTTTCTAAATTA
CATAAAGCAGATGAAAAGCCACACTATGCTGAAAATAGTGTGTGGATGCATCTACATGAT
GATGCAACACGAATTGGATTTTTTAGCTTGCTTATAAAACATTTTGGAACTTGCCGTTAA
TGACTCCGATTTGTCCACCAAATTATCCAACTTTTCACCTCTTTGTAAAACATTCTCAAT
CGTTTTGTGCAAAACGATTTTCGTCTCATCCAGTTCTTGTTGAACTTTCATGATAGCGTC
AGCCTGTGAAGGATCTTGATATTTGCTAATGTAAGTGTCCAGTTGCTTCATTTTCAATGC
ATCATTGGTCTCAGTCACATCTGCCCACTCTTCCTTAGGATGTGCGACTAAATATTCATC
CAATATTTTGTTTAATAGTGTGTATGCTGGTCTGACAGGATATTCTTTGTCGGTGATCAA
AACACCACATATGCCCTCACTCCTGGCATAAACGTGGCCAATATAGTTGCCTTCTTCTAT
ACTTTGTCTTTGTCCTGCACCAGTTCTAGAAGCGACCGTTTCAGCAAAAAAAGTCATAAA
CTGGCCAACACTAGACCTTTCAAAGAAACCAAATTGTGACAAGTCTTTAACTTCACTCAA
CTCTAGAGCCTTTTCTCCTCCAGAGCGAAATACACCGATGTAGTAGATTCTCATTGCCAA
AATAACTTCTCTAGTGATACGTAAAGCTTCAGAAATGCCCTAGCCTGGTCTAACGCAGTC
AAACTGTGCCAGAGACTTTTGTATATTGTTCATGTTGATATCTATTGTGCTTGCTCTTGA
TTTCACACCAAGCCAATCGTTCTGTACGGCACGCCACCCAATAAGAAAAAAAGGGAAAAG
GAGCCGAATTTTGGTTTAAAAACATATAATGCTGAAATTGTGGAACACCAATTACCAACT
GGAAGTAGGCTCGATCCAAAGAGTGTATATTATCAGTAAA
Chr coordinates
Chr XI from 75821-77032