Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
IRS4
Systematic Name
YKR019C
Strain
S288c
Description
EH domain-containing protein; involved in regulating phosphatidylinositol 4,5-bisphosphate levels and autophagy; Irs4p and Tax4p bind and activate the PtdIns phosphatase Inp51p; Irs4p and Tax4p are involved in localizing Atg17p to the PAS; IRS4 has a paralog, TAX4, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>IRS4 YKR019C
ATGAGACTTTCGTTTGGTAAACAGCGTTATCATGGCGGTACAACAGTAACTTTGACTGAA
CAAGGAGCTTCAGATTCCCTTCGCGCTGCGCAAGCTATCTTCCAGAACCATTCCAATGAG
GTCAGCAGTCCATGCCCTCCAGTAACGGTGAGCAGGAATCCTCAAACTAGGTTATCAGAG
CCATCGCTACAAAAGTCAGGGCGGAAACAAGAACAAAAGAAGGCACGCATACGAACAAAA
CAGGTACCTAAGATTAAAACAACGGCGCCTAATGATGTTGAGTTGTCTAAGAAACACAGG
TCAAGCCCTGCAGGTAAAGATAATGTTAGTAGTACTGCTCAAATGGCAGCTGCTTTAGCG
CATTCACAATCGAAACTTAGTTCTGACAATAACTCCTCCCATTCTTCGGCATTGGATACA
CTAAAAGTTCTAGAAACTCCGAACTTGAATGGCTTGCTGGGCATTCATTCACGCTCAAGC
TCAAGAAACGGCTCCAATGAATCACTGACGCCTGGCCAAAGAACTCCCGACAATAGATCT
CAAGAGAATTTACTTACTTCCTTTAGTAGCGGTAGAAGGCTATCCTCGAGCTCTATGGAG
CCTGCAACTAATAAAGACAGCAACAAAGCTCTGCCCAAACGCAGGCCGTCTCCTCCCTTG
CAATCATCACTTGTCGGCAGTGGTCAGCTTCATGAAAATGAAAACCTATCATCAATTAGC
ATCGATTCCAGACATAGTCTCAATCCGGACACTTCAGACGTTATTTCTAATAGGTCACAA
ACAAGTCTATCTCAAACAATTAATCAACTCTCGTTATGTGAATCAGAGCCATCTATTGCA
AGCTCAAACACTACTACTACAACGAGCAACCAGGGAAGTGGTTTGCCCAACTTGGTTCCG
AACTATTCATCCGATATGAGGAAGAAGAAGCTTGTTAACAAGTTCAAAAGGAAAGTATTT
GGTAGTAAGCCCAAGCACTTATCTTCACAATATGAAATGGATGCAAGCAGCGAAGAACTG
GGACAACATGAACAACAACCGAGTATGAGATTTAAAACAACATTACGTAAAACCTCTGTA
AGTACAAACGCAGAAAATGATCATGCATCCTCTCTACATGAGGGAAATCTGAGGTATAAG
TACAATCCGTCCAACGACACGTATGATGTGTATGACGATACTGATTCTGATTCTGAATCT
GATCAGAACCAGGACGCCTTGACCAAGCCACGCAAAAGAGATAGAATTAAGAGAAAGATC
AGGAATTCTGCCAATAAAACTGCACATCATAGGCCTATCCACCGCACGAGAGATCGGAAA
TTCAATGAGGATAAACCCTGGAAATCACATACAGATATAACTTTCGTAACAGACAACGAA
AGGAAGCGTTACGAAAGCATGTGGGTAAGCAACAGACACCGTCATTTGAACCTGTTGAGC
TGGTGGCCCTCTATAACGGGTGATTCCGGAGCAATTAATACTTTACCCGAAGATGGATTG
ATATTGGGTATCATAGTCCGTGATATCTGGAAGCGGTCTAACTTGCCCAATAGTCTATTG
GCAGAAATTTACACGAAGGTAGACACAAGAAAAGATGGTACTTTAGATAGGAAATCTTTT
ATTGTGGGTATGTGGCTGGTCGATCAGTGCCTGTATGGCAGAAAACTTCCCAATGTTGTC
GAGCAATGCGTTTGGGATAGCGTAGATAGATATGCTTCCACCACGGTTGTGCCAGTGAGT
ACGCTAAAGGCGATGGCCAAACAAAAGAGAAAACAGATGAAAGAAGAAATCAAGAATATC
AAGAAGGAAAACCGTGTAGTTCTTGTAGACCACAATAGCTCGTCGTGA
Promoter Sequence
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>IRS4 YKR019C
TCGCTCAAAGAGGTAAAAAGACGGCGCTATTATATATCTGCGTATATATACTACAAACAG
CCGGGAATACATTTGGCAAAGTCCTCGTACGACAATAGGGCAATTGCTAGTAGTGTTAAG
CAGTTTTTCAGGTGAACTTGCAAACCGAAAAAGAGGAAAAATTGGTTCACATAGTAAAAT
GCACTCTCTCGAAGGAAGTGTTCGGTGAAAGCCACGATATGCCGCTGGAAATTACAGTTC
CTTGATTAAAGATTCTACTGTTTGCTTCAACTTGTTAATTTGGTCTTCATTGGCGTTTGT
AATTTCTTTGAGAAGGTCGTTGACTTTTATTAGGTCATAATAGTTTTCGTAAATGGTATT
CTTGATAGAATTGTTAGTCTCGGTTTCTTTGCCCAAGAGCTTATTGTGAATTTGTACTAG
CCTCTTAAAGGGCAGGTTCTTTATCTCTTCTTCTGCATCTTCTGACCCCTCCTTGAGATC
CTCTTCAGTTGCACTCAATTCGTCATCTTTCACTGGTTTCTCAGTGTTTGCTTCGGTATC
TATATTCACATCTGTGACTTGCTCCTCCCCAGAATGAGCCTCGCTGGCTTTTTCCCCTAT
ACGTGCTTCTTGACGACCTTTATTCGGTTCATTTTCCAAGTTGTAGAATTCTCTTAAGAG
CAATCTTCTATCTTTGTTCAGACTGCTCACCCTCAGGGACTTTTTGTGACTAATTTGTTC
TGCCATCTGTACTTAATATCCTCGTCAGATTCCGTCTCACCGCAAATACGCCTCTTCTAT
GCAGAGCCTCACCTATACGTACAACTTACTGCCTCTTGTTTCCACGCAGCGAAAATTCGA
TGATTTCTCGTATAAAGCATATCGAAGTTGAATCATCACAAAAAGGCCCATTGTGTAATG
GACCCTTGCCACAACAACACTCTCGTTGCACAGGTAGAACATACTTTTAAGGCCTGGGTA
GATTCATTTTTTTGACATAGGAAAAGATTAGCAGAGGAGT
Chr coordinates
Chr XI from 478063-476216