Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name IRS4
Systematic Name YKR019C
Strain S288c
Description EH domain-containing protein; involved in regulating phosphatidylinositol 4,5-bisphosphate levels and autophagy; Irs4p and Tax4p bind and activate the PtdIns phosphatase Inp51p; Irs4p and Tax4p are involved in localizing Atg17p to the PAS; IRS4 has a paralog, TAX4, that arose from the whole genome duplication
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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>IRS4 YKR019C
ATGAGACTTTCGTTTGGTAAACAGCGTTATCATGGCGGTACAACAGTAACTTTGACTGAA
CAAGGAGCTTCAGATTCCCTTCGCGCTGCGCAAGCTATCTTCCAGAACCATTCCAATGAG
GTCAGCAGTCCATGCCCTCCAGTAACGGTGAGCAGGAATCCTCAAACTAGGTTATCAGAG
CCATCGCTACAAAAGTCAGGGCGGAAACAAGAACAAAAGAAGGCACGCATACGAACAAAA
CAGGTACCTAAGATTAAAACAACGGCGCCTAATGATGTTGAGTTGTCTAAGAAACACAGG
TCAAGCCCTGCAGGTAAAGATAATGTTAGTAGTACTGCTCAAATGGCAGCTGCTTTAGCG
CATTCACAATCGAAACTTAGTTCTGACAATAACTCCTCCCATTCTTCGGCATTGGATACA
CTAAAAGTTCTAGAAACTCCGAACTTGAATGGCTTGCTGGGCATTCATTCACGCTCAAGC
TCAAGAAACGGCTCCAATGAATCACTGACGCCTGGCCAAAGAACTCCCGACAATAGATCT
CAAGAGAATTTACTTACTTCCTTTAGTAGCGGTAGAAGGCTATCCTCGAGCTCTATGGAG
CCTGCAACTAATAAAGACAGCAACAAAGCTCTGCCCAAACGCAGGCCGTCTCCTCCCTTG
CAATCATCACTTGTCGGCAGTGGTCAGCTTCATGAAAATGAAAACCTATCATCAATTAGC
ATCGATTCCAGACATAGTCTCAATCCGGACACTTCAGACGTTATTTCTAATAGGTCACAA
ACAAGTCTATCTCAAACAATTAATCAACTCTCGTTATGTGAATCAGAGCCATCTATTGCA
AGCTCAAACACTACTACTACAACGAGCAACCAGGGAAGTGGTTTGCCCAACTTGGTTCCG
AACTATTCATCCGATATGAGGAAGAAGAAGCTTGTTAACAAGTTCAAAAGGAAAGTATTT
GGTAGTAAGCCCAAGCACTTATCTTCACAATATGAAATGGATGCAAGCAGCGAAGAACTG
GGACAACATGAACAACAACCGAGTATGAGATTTAAAACAACATTACGTAAAACCTCTGTA
AGTACAAACGCAGAAAATGATCATGCATCCTCTCTACATGAGGGAAATCTGAGGTATAAG
TACAATCCGTCCAACGACACGTATGATGTGTATGACGATACTGATTCTGATTCTGAATCT
GATCAGAACCAGGACGCCTTGACCAAGCCACGCAAAAGAGATAGAATTAAGAGAAAGATC
AGGAATTCTGCCAATAAAACTGCACATCATAGGCCTATCCACCGCACGAGAGATCGGAAA
TTCAATGAGGATAAACCCTGGAAATCACATACAGATATAACTTTCGTAACAGACAACGAA
AGGAAGCGTTACGAAAGCATGTGGGTAAGCAACAGACACCGTCATTTGAACCTGTTGAGC
TGGTGGCCCTCTATAACGGGTGATTCCGGAGCAATTAATACTTTACCCGAAGATGGATTG
ATATTGGGTATCATAGTCCGTGATATCTGGAAGCGGTCTAACTTGCCCAATAGTCTATTG
GCAGAAATTTACACGAAGGTAGACACAAGAAAAGATGGTACTTTAGATAGGAAATCTTTT
ATTGTGGGTATGTGGCTGGTCGATCAGTGCCTGTATGGCAGAAAACTTCCCAATGTTGTC
GAGCAATGCGTTTGGGATAGCGTAGATAGATATGCTTCCACCACGGTTGTGCCAGTGAGT
ACGCTAAAGGCGATGGCCAAACAAAAGAGAAAACAGATGAAAGAAGAAATCAAGAATATC
AAGAAGGAAAACCGTGTAGTTCTTGTAGACCACAATAGCTCGTCGTGA
Promoter Sequence
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>IRS4 YKR019C
TCGCTCAAAGAGGTAAAAAGACGGCGCTATTATATATCTGCGTATATATACTACAAACAG
CCGGGAATACATTTGGCAAAGTCCTCGTACGACAATAGGGCAATTGCTAGTAGTGTTAAG
CAGTTTTTCAGGTGAACTTGCAAACCGAAAAAGAGGAAAAATTGGTTCACATAGTAAAAT
GCACTCTCTCGAAGGAAGTGTTCGGTGAAAGCCACGATATGCCGCTGGAAATTACAGTTC
CTTGATTAAAGATTCTACTGTTTGCTTCAACTTGTTAATTTGGTCTTCATTGGCGTTTGT
AATTTCTTTGAGAAGGTCGTTGACTTTTATTAGGTCATAATAGTTTTCGTAAATGGTATT
CTTGATAGAATTGTTAGTCTCGGTTTCTTTGCCCAAGAGCTTATTGTGAATTTGTACTAG
CCTCTTAAAGGGCAGGTTCTTTATCTCTTCTTCTGCATCTTCTGACCCCTCCTTGAGATC
CTCTTCAGTTGCACTCAATTCGTCATCTTTCACTGGTTTCTCAGTGTTTGCTTCGGTATC
TATATTCACATCTGTGACTTGCTCCTCCCCAGAATGAGCCTCGCTGGCTTTTTCCCCTAT
ACGTGCTTCTTGACGACCTTTATTCGGTTCATTTTCCAAGTTGTAGAATTCTCTTAAGAG
CAATCTTCTATCTTTGTTCAGACTGCTCACCCTCAGGGACTTTTTGTGACTAATTTGTTC
TGCCATCTGTACTTAATATCCTCGTCAGATTCCGTCTCACCGCAAATACGCCTCTTCTAT
GCAGAGCCTCACCTATACGTACAACTTACTGCCTCTTGTTTCCACGCAGCGAAAATTCGA
TGATTTCTCGTATAAAGCATATCGAAGTTGAATCATCACAAAAAGGCCCATTGTGTAATG
GACCCTTGCCACAACAACACTCTCGTTGCACAGGTAGAACATACTTTTAAGGCCTGGGTA
GATTCATTTTTTTGACATAGGAAAAGATTAGCAGAGGAGT
Chr coordinates Chr XI from 478063-476216
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