Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
TIF1
Systematic Name
YKR059W
Alias
eIF4A
Strain
S288c
Description
Translation initiation factor eIF4A; DEAD-box RNA helicase that couples ATPase activity to mRNA binding and unwinding; ATP hydrolysis accelerates the recruitment of mRNA during 48S preinitiation complex (PIC) assembly; ATPase activity stimulated by either eIF4G1 or by the PIC in an eIF3g and eIFGi subunit-dependent manner, independent of eIF4E and eIF4G; subunit of the mRNA cap-binding protein complex (eIF4F) with eIF4E and eIF4G; protein abundance increases in response to DNA replication stress
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>TIF1 YKR059W
ATGTCTGAAGGTATTACTGATATTGAAGAATCCCAAATTCAAACCAACTATGACAAGGTT
GTCTACAAGTTCGATGATATGGAATTGGACGAAAACTTGTTAAGAGGTGTTTTCGGTTAC
GGTTTCGAAGAACCATCTGCCATTCAACAACGTGCCATCATGCCTATTATTGAAGGTCAC
GATGTCTTGGCTCAAGCTCAATCTGGTACTGGTAAGACCGGTACCTTTTCCATTGCTGCT
TTGCAAAGAATTGACACCTCTGTCAAGGCTCCTCAAGCTTTGATGTTGGCTCCAACTAGA
GAATTGGCTTTGCAAATCCAAAAGGTTGTCATGGCTTTGGCTTTCCACATGGACATCAAG
GTCCACGCTTGTATCGGTGGTACTTCCTTTGTTGAAGACGCTGAAGGTTTGAGAGATGCT
CAAATCGTCGTTGGTACTCCAGGTCGTGTTTTTGACAACATCCAAAGACGTAGATTCAGA
ACTGACAAGATCAAGATGTTCATCTTAGATGAAGCTGATGAAATGTTGTCTTCTGGTTTC
AAGGAACAAATCTACCAAATTTTCACCTTACTTCCACCAACCACTCAAGTTGTTCTATTG
TCCGCCACCATGCCAAATGACGTCTTGGAAGTTACCACCAAATTTATGAGAAACCCAGTT
AGAATTTTGGTTAAGAAGGATGAATTGACTTTGGAAGGTATCAAACAATTCTACGTTAAT
GTTGAAGAAGAAGAATACAAATACGAGTGTTTGACCGATTTATACGACTCTATCTCCGTT
ACTCAAGCTGTCATCTTCTGTAACACCAGAAGAAAGGTCGAAGAATTGACCACTAAGTTA
AGAAACGACAAATTTACCGTTTCTGCCATCTACTCTGATTTACCACAACAAGAAAGAGAC
ACCATCATGAAGGAATTCAGAAGTGGTTCTTCCAGAATTTTGATCTCCACTGATTTGTTG
GCTAGAGGTATCGATGTCCAACAAGTTTCTTTGGTTATTAACTACGACTTACCAGCTAAC
AAAGAAAACTATATTCACAGAATCGGTAGAGGTGGTCGTTTCGGTAGAAAGGGTGTTGCC
ATCAACTTTGTTACTAACGAAGACGTTGGCGCTATGAGAGAACTAGAAAAGTTCTACTCC
ACTCAAATTGAAGAATTGCCATCCGACATCGCTACTTTGTTGAACTAA
Promoter Sequence
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>TIF1 YKR059W
GGAACTAAACAGCTCTTATAGCGTTGTGAGTACTCAAGCTGATAGCGATGAGCACCAAAA
TGCAGAAGAGGAGGATAGTACGACAGATAACGCTTCAAATTCTGGAGAAGAAAGCCACCT
CGATGATATAAGCACGGCCGCTTCTTCCAATAACAATGTAAGTAATCAACCAGATGGCAA
AAATTTTAGCAATTCTAAAGAAAATAATATCAGTGTCGAATCTAGCCCTTCAAATCCAGA
ACAGAAAAGGTCAACTGACAATATACAAAAACCAAGTGTTTCTACTAATGACTTACCAGA
CGACGTAGAACCACATACCTCTGTTGATGACAATATACAGTACTTAGAAAAAGACAAGGA
AGGTTATGAAGAATTTCTTCCGGACGTGTACGAGTCAAATGCAATCGATAACGAAGAAGA
ATTTTTTGATGACGATGCAAGAGATGCTACCGAAGGAGAAACGAAGACGAGTGCAGTTGC
AGATAAACAGGAGGATATGAAACTTACAGCAGAGGAAACCAACCAACCGCAACAAGAAAT
GCCCAACTTCAAATTTGACTGGGAGGACTCTGATTATCTATCCAAAGTAGAGAGGTGTTT
CCCTGATGATATTTTTGAGTATGCAGTAGAGTAAACTTCCACGCACATATTAGGAAAATT
AAAAGACATATCTATGTAAAGACCTTTTCGACTATACAAAAATGCATAACTATTCTATAT
ACATTCAAACTCGAAATTTACTTTAAAGGTTTATCAGCAACAACATCCGATGCTTGCTGT
TTATCTTTTCTCACCTCACAACGTTTATAGTGACTGAAAAATTTTTGCATTCTCACCTCG
TCTATTGAATGATGTGCTAAGAACTTGAGCTAACATCACAGAACAAAGGTATGAATATAC
GCAGCCCTGACATTTGTAGATTTTTTATTTGGTCTCTAGTCTTTTCTTTTCTTATTTTAT
AACAAATTCGTTAAACGGCCTCCTTCTAATTATATACAAG
Chr coordinates
Chr XI from 554987-556174