S.cerevisiae - Yeastract

Locus Information

Standard Name	SRL3
Systematic Name	YKR091W
Alias	WHI7
Strain	S288c
Description	Repressor of transcription at Start; binds to SBF (Swi4p-Swi6p) at SCB promoter elements in G1 to repress transcription; inhibitor of Start that retains Cdc28-Cln3 at the ER; acts with Ydj1p to promote release of the complex in a growth-mediated positive feedback loop to trigger Start; Srl3p is unstable and degraded by SCF-Grr1 after Cdc28p-dependent phosphorylation; contains a GTB (G1/S transcription factor binding) motif; binds SBF-regulated promoters in HU-treated cells; Cdc28p substrate
External sources	Open in SGD Open in KEGG

Gene Sequence Download FASTA View Seq	Sequence hidden
Promoter Sequence Download FASTA	>SRL3 YKR091W ACGGCGGCACTACGAGATACAGCTCTGATGCAGATTATAAAGAAACGGAGCCCATTGAGT TTAAATATCCGCCTGGGGAGGGACCTTGCAGAGCATGCGGCTTGGAAGTCACAGGGAAAA GAATGTTTTCCAAAAAGGAAAACGAACTGTCGGGTCAATGGCATCGTGAATGTTTTAAAT GCATTGAATGTGGTATCAAATTCAATAAACATGTTCCCTGTTATATTCTAGGCGATGAAC CATATTGTCAAAAGCACTATCACGAGGAGAATCACAGTATTTGTAAGGTTTGTTCAAATT TCATAGAGGGTGAATGTCTGGAAAATGATAAGGTGGAACGATTCCACGTGGATTGTCTAA ACTGTTTCTTATGCAAGACTGCCATTACTAATGATTATTATATATTCAATGGGGAAATTC CATTGTGCGGTAATCACGACATGGAAGCTCTCTTGAAGGAAGGTATCGACAATGCTACAT CAAGCAATGATAAGAACAATACTCTCTCTAAAAGGAGAACGAGGCTCATCAACTTCAACT AGCATCACTACCCATTTGTCTTTCCTAGCACACATGTTTCATAACATTCTTAATAAGATT TTGATTTTTTATATTATTAGCCAGCCTTGTTCATTTATAAATTGTATAGCGCAGGAAAAA GGCATCTGCCTATCTATGGTATCAACAACATTAGTCGTCATTAGTTAGTTAGTTATAAAG ACATCATTCACTCATATTCACTACGTTGTCTTCTTCTCAACAACTACCTCTAACTGTTTT TTTACGCGTCATTTAATTGTAGCGAATTTCTATTTTTGGACATTCTCGTACCGGTGCATT AAAGGCTAAAAGCTAAAAAGGGAACAGGAGCCTAAGAATAGAGAATAAGGAAATTTATTT AAGGAAAGGCTAAGCAATGAAATGTTTCGTTATTTTATTGTATTTTCAAGAGGATGGAAG AAGAACCTGAGCACAAACGGATAAATAATAGACGAATATA
Chr coordinates	Chr XI from 611525-612265