Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
RTT109
Systematic Name
YLL002W
Alias
KAT11, KIM2, REM50
Strain
S288c
Description
Histone acetyltransferase; critical for cell survival in presence of DNA damage during S phase, required for recovery after DSB repair; acetylates H3K56, H3K9; H3K56 acetylation activity required for expression homeostasis, buffering of mRNA synthesis rate against changes in gene dosage during S phase; involved in non-homologous end joining and regulation of Ty1 transposition; prevents hyper-amplification of rDNA; interacts physically with Vps75p
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>RTT109 YLL002W
ATGTCACTGAATGACTTCCTAAGTTCCGTGCTACCTGTCAGTGAACAATTTGAATACTTA
TCGTTGCAATCTATTCCGTTAGAAACCCATGCTGTCGTAACCCCAAATAAGGACGACAAA
AGGGTCCCAAAAAGCACGATCAAGACTCAACACTTCTTTAGTCTATTTCACCAAGGAAAA
GTTTTTTTTTCATTAGAAGTGTATGTGTATGTCACGCTTTGGGATGAAGCAGATGCCGAA
CGGTTAATATTTGTATCAAAGGCAGACACTAATGGTTATTGTAATACGAGGGTAAGCGTT
AGAGATATTACAAAAATAATATTAGAATTTATATTATCAATCGACCCGAATTACTATCTT
CAAAAAGTAAAACCGGCAATAAGATCATATAAGAAGATATCCCCCGAGCTGATTAGCGCA
GCCAGTACGCCAGCAAGAACTTTAAGGATTTTGGCTAGAAGGCTTAAACAGTCAGGCAGC
ACCGTTTTGAAAGAAATAGAATCTCCACGTTTTCAACAAGATCTTTATCTCTCATTCACC
TGTCCTCGTGAGATTTTGACCAAAATTTGTTTATTTACTAGACCTGCATCCCAGTACCTC
TTCCCAGATTCTTCAAAAAACAGCAAAAAGCATATACTAAATGGCGAGGAACTAATGAAA
TGGTGGGGCTTTATTTTGGATAGATTACTAATTGAATGCTTTCAAAATGATACACAAGCA
AAATTAAGGATACCGGGCGAAGATCCTGCTCGAGTAAGATCATACCTAAGAGGGATGAAA
TATCCACTATGGCAAGTGGGTGATATATTTACCTCTAAAGAAAATTCTCTTGCGGTATAT
AATATTCCATTATTCCCAGACGATCCTAAGGCTAGATTTATACACCAATTGGCAGAGGAA
GATCGCCTCCTCAAAGTAAGCTTATCATCCTTCTGGATTGAACTACAAGAGCGTCAAGAG
TTCAAATTAAGTGTCACATCATCTGTAATGGGTATTTCGGGATACTCTCTTGCCACTCCA
TCTTTATTTCCATCTAGTGCCGATGTTATTGTACCGAAGTCAAGGAAGCAGTTTAGGGCA
ATCAAGAAGTACATTACTGGAGAGGAATACGATACAGAGGAAGGCGCAATAGAAGCTTTC
ACCAATATTCGTGATTTTCTATTGCTCAGAATGGCAACAAATCTTCAATCTTTAACAGGG
AAGAGGGAGCATCGGGAGAGAAATCAGCCGGTTCCTGCAAGCAACATCAACACGTTGGCG
ATAACAATGCTAAAACCGCGTAAAAAAGCTAAAGCCTTGCCTAAAACTTGA
Promoter Sequence
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>RTT109 YLL002W
ATTTAGAGAAAGACTTTTAGAGATAGTAAAATCAGAAGAATTAGCAGACGAAGTTCGCGA
AGAATTTGTGTTAGTCAAGACGTTTTATATTTGGAAAACTCATCTAGACGAAATATTTTA
TATGAGTACATTATTGGAACAATCGGAAGCTAATAAACAATTCATAATTACATCCAAATT
CTTGAAAATGTGGAGTCTTCGATTCCTAAAAATTAAGCGTAATGATGAGACAGTCGAGGT
GTTTCGTCATCGGTGGGACAGGGCCACTGTAAGGGGATTGTTATTATTATGGAAAAATCG
TTCAGACAGTTCTCCAAAGAGAAGGAAGGACTTCAATCTTAAACATGAACTAAAAACTCC
CATAAGATCAGACTCTCAAAACGCCTCAACCATACCAGGCTCAGAAAGAATAAAGCAGCA
CAGAATGGAAGCGATGAAGTCGCATTATAGCAGGGCAAGAAGAGCCATACCAAGTCCGGT
GAAATCTTCCAGTGTTCTTGATTCTACAGCTAAAAAACAGATCAACCTTGAAAGTACGAC
AGGCTTAAACGGATCTCCGACGCGAGGAAAACCTCTAAGGTATTCTCCTAGGCGTACCAC
TAGAAACATGCCATCCAAAGTTGACCATATTGATTTTGGCAGAATACCCGCTGTACCTTT
TAGCCTAAGCGCCAATTCTCCTAAAATCGATCAAGATATGGATTATATAAGAGAGCATGA
TAAATCCCCGTTAAGTCGTAAACGTCAATAGATATATATATTATGTACGTATGTATGTGT
GCATATGTAGTCGTAACCTTTCTTGCTTCTGAGATGCATACAATTACTAATAATATTCTC
CAGGTCTATGAAAACATCACAACATACTATACTTTTCGTGTTCGCGTTGTAAGCTATAAT
GGAAAATGGACGCCATAACGCATTACTTAACAAACTACAGTTTGTCAATAGAGTTGTCCA
GTAGAGTTAAAAGGTCAATTCAACCGGTCTTCAATAAGAC
Chr coordinates
Chr XII from 146291-147601