Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
HSP104
Systematic Name
YLL026W
Strain
S288c
Description
Disaggregase; heat shock protein that cooperates with Ydj1p (Hsp40) and Ssa1p (Hsp70) to refold and reactivate previously denatured, aggregated proteins; responds to stresses including heat, ethanol, and sodium arsenite; involved in [PSI+] propagation; protein becomes more abundant and forms cytoplasmic foci in response to DNA replication stress; potentiated Hsp104p variants decrease TDP-43 proteotoxicity by eliminating its cytoplasmic aggregation
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>HSP104 YLL026W
ATGAACGACCAAACGCAATTTACAGAAAGGGCTCTAACGATTTTGACGTTGGCTCAAAAA
TTGGCTTCGGATCATCAACATCCACAATTACAACCTATACATATTCTAGCTGCCTTCATT
GAAACGCCAGAAGATGGATCAGTCCCTTACCTACAGAATCTAATTGAGAAGGGCCGTTAC
GACTATGATCTTTTCAAGAAAGTGGTTAATAGAAATCTAGTAAGAATTCCTCAACAGCAA
CCTGCACCTGCGGAGATAACTCCAAGTTATGCTTTGGGGAAAGTCCTTCAAGACGCTGCT
AAGATTCAAAAACAACAGAAGGACTCATTTATAGCGCAAGACCATATATTGTTTGCTCTA
TTCAATGATTCGTCTATTCAGCAAATATTTAAGGAAGCTCAAGTAGATATTGAGGCCATC
AAGCAACAAGCTCTTGAACTTCGTGGTAACACTAGAATTGACTCTCGTGGCGCTGATACG
AACACACCTTTGGAATATTTATCAAAGTACGCCATTGATATGACTGAGCAGGCTCGTCAA
GGTAAACTTGACCCTGTCATCGGCCGTGAAGAAGAAATAAGAAGCACTATTAGAGTTTTA
GCAAGAAGAATTAAGTCCAACCCATGTTTAATTGGTGAGCCAGGTATCGGTAAGACCGCT
ATTATTGAAGGTGTTGCTCAAAGAATCATTGACGATGACGTTCCCACTATCTTACAAGGC
GCTAAATTGTTCAGTCTAGATTTGGCCGCATTAACCGCAGGTGCTAAATACAAAGGTGAT
TTCGAAGAAAGATTCAAAGGTGTTTTGAAGGAAATCGAAGAATCAAAGACTCTAATTGTG
TTATTCATTGATGAAATTCACATGTTAATGGGTAATGGTAAGGACGACGCTGCTAACATC
TTGAAGCCAGCTTTGTCCAGAGGCCAATTGAAGGTCATCGGTGCCACCACCAATAACGAA
TATAGATCTATTGTGGAAAAGGATGGTGCCTTTGAAAGAAGATTCCAGAAAATTGAAGTC
GCTGAACCAAGTGTGAGACAAACAGTGGCCATATTGAGAGGTCTGCAACCAAAGTATGAA
ATACATCATGGTGTAAGGATTCTGGATAGCGCCTTAGTCACTGCTGCTCAATTAGCCAAG
CGTTACTTGCCATATAGAAGATTGCCAGATTCTGCTTTGGATTTAGTTGATATTTCTTGT
GCTGGTGTCGCCGTCGCAAGAGATTCTAAGCCAGAAGAATTGGATTCCAAGGAACGTCAA
TTGCAATTGATTCAAGTAGAGATAAAAGCTCTAGAGAGAGATGAAGATGCCGACTCCACC
ACTAAAGATAGATTAAAGTTAGCTAGGCAGAAGGAAGCTTCATTGCAAGAAGAATTGGAA
CCTCTAAGACAACGTTACAATGAAGAAAAGCATGGCCATGAAGAATTGACACAAGCTAAA
AAGAAATTGGATGAACTGGAAAACAAGGCCCTTGATGCTGAACGTAGATATGATACTGCT
ACCGCCGCTGATTTAAGGTACTTCGCCATCCCAGATATCAAAAAGCAAATCGAAAAGCTT
GAAGATCAGGTTGCTGAGGAAGAGAGACGTGCTGGTGCCAACTCCATGATCCAAAATGTG
GTCGATTCAGACACCATTTCTGAAACAGCTGCAAGATTGACTGGTATCCCTGTTAAGAAG
TTGTCAGAATCTGAAAATGAAAAATTGATTCATATGGAACGTGACTTATCATCTGAAGTC
GTGGGCCAAATGGATGCCATTAAAGCTGTTTCCAATGCCGTTAGATTGTCTAGATCAGGT
TTAGCTAATCCAAGGCAACCAGCATCCTTCTTATTTTTAGGTTTGTCCGGTTCCGGTAAA
ACTGAATTGGCTAAAAAAGTTGCTGGATTTTTGTTTAATGATGAGGACATGATGATCAGG
GTCGATTGTTCTGAATTAAGCGAGAAGTATGCGGTCTCTAAGTTGTTGGGTACCACGGCA
GGTTATGTCGGGTACGATGAAGGTGGCTTTTTAACTAACCAACTGCAATACAAACCATAC
TCCGTTTTGTTATTCGATGAAGTAGAAAAGGCACATCCTGATGTTTTGACTGTCATGCTA
CAAATGTTGGATGACGGTAGAATTACTTCTGGTCAAGGTAAGACGATCGACTGTTCCAAT
TGTATTGTCATCATGACTTCCAATCTAGGTGCTGAATTTATCAATTCTCAACAAGGATCA
AAGATCCAAGAATCTACCAAGAATTTGGTCATGGGTGCTGTTAGGCAACATTTCAGACCA
GAATTTTTGAACAGAATTTCTAGTATAGTCATTTTCAACAAGCTATCTAGAAAAGCTATT
CATAAGATCGTGGATATTCGTTTGAAGGAAATTGAAGAGAGATTCGAGCAAAATGATAAA
CATTACAAGTTGAATTTAACTCAAGAGGCCAAGGACTTCTTGGCCAAATATGGTTATTCC
GATGATATGGGTGCACGTCCACTGAACAGGTTAATTCAAAACGAAATTTTGAACAAACTG
GCACTAAGGATCTTAAAGAATGAAATCAAGGATAAGGAAACTGTCAATGTCGTCTTGAAG
AAGGGTAAATCTCGTGATGAAAATGTTCCTGAGGAAGCTGAAGAATGTCTGGAAGTTCTA
CCAAATCACGAAGCTACTATAGGGGCTGACACGTTAGGTGATGACGATAATGAGGACAGT
ATGGAAATTGATGATGACCTAGATTAA
Promoter Sequence
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>HSP104 YLL026W
TTTCCAATCAGAGCAAGAGTAGCAAGGCTTCTAAAAGCCCGAAGTGGTCGAGCTACGCAT
TCCCTTCGCGTGAGACCATCAAATCTCATGAGGAGGCCATCAAGAAGCAGAATAAAGCTA
TAGACGAGCAAATAGCTGCTGCAGTATCCAAGAATGACTGCTCTTGCACAGAACCTCCCA
AGAAAAGAAAGAGGAAATTGAGACCAAGAAAGGCGCTGATCACCCTGAGTCCGAAGGCAA
TCAAGCATTTAAGGGCACTGCTAGCTCAGCCGGAACCTAAATTGATTAGAGTTAGCGCTA
GAAACCGTGGATGTTCAGGACTAACGTACGATCTACAATATATCACCGAGCCGGGGAAAT
TCGATGAGGTAGTAGAACAAGATGGCGTTAAAATTGTCATCGATTCAAAGGCGTTATTCA
GCATCATTGGAAGTGAAATGGACTGGATCGACGACAAGTTGGCCTCTAAGTTTGTCTTCA
AGAATCCAAACTCCAAGGGCACATGCGGTTGTGGCGAGAGTTTCATGGTTTAAAAACCTT
CTGCACCATTTTTAGAAAAAAAGAATCTACCTATTCACTTATTTATTCATTTACTTATTT
ATTTACATATTTATCATACATATTAACATTGAACCCTCCATCGTGGTAGTGTTTGCTGTT
CCTAACTTTTCTTTCGTTGTTCTTGTAGATATATATTTTTCCAGAATTTTCTAGAAGGGT
TATTAATTACAATCTTAAACGTTCCATAAGGGGCCGCGATTTTTTTGTTCAATTTTCAAC
AGGGGGCCCATCTCAAAGAACTGCAAATTATATCACAGTAAAAGGCAAAGGGGCGCAAAC
TTATGCAACCTGCCAGATTATTATATAAGGCATTGTAATCTTGCCTCAATTCCTTCATAA
TTCGTTCCTTTGTCACTTGTTCCTTTTTACCCTTGAATCGAATCAGCAATAACAAAGAAA
AAAGAAATCAACTACACGTACCATAAAATATACAGAATAT
Chr coordinates
Chr XII from 88623-91349