Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
ISA1
Systematic Name
YLL027W
Strain
S288c
Description
Protein required for maturation of mitochondrial [4Fe-4S] proteins; functions in a complex with Isa2p and possibly Iba57p; isa1 deletion causes loss of mitochondrial DNA and respiratory deficiency; depletion reduces growth on nonfermentable carbon sources; functional ortholog of bacterial A-type ISC proteins; human ISCA1 can complement isa1 null mutant
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>ISA1 YLL027W
ATGATAAACACAGGAAGAAGCAGGAATTCAGTACTGCTGGCACACAGATTCCTTTCAACT
GGAGGATTTTGGCGAGGCGGTACGAATGGCACAATGTCTCGCACAATCAACAACGTAAAT
CCTTTCAAATTAAAATTCATACCGAAGACAGTGCCCGCAGCTGCAGACTCTGTCTCTCCA
GATAGTCAACGTCCAGGTAAGAAGCCCTTCAAATTCATAGTTTCCAATCAGAGCAAGAGT
AGCAAGGCTTCTAAAAGCCCGAAGTGGTCGAGCTACGCATTCCCTTCGCGTGAGACCATC
AAATCTCATGAGGAGGCCATCAAGAAGCAGAATAAAGCTATAGACGAGCAAATAGCTGCT
GCAGTATCCAAGAATGACTGCTCTTGCACAGAACCTCCCAAGAAAAGAAAGAGGAAATTG
AGACCAAGAAAGGCGCTGATCACCCTGAGTCCGAAGGCAATCAAGCATTTAAGGGCACTG
CTAGCTCAGCCGGAACCTAAATTGATTAGAGTTAGCGCTAGAAACCGTGGATGTTCAGGA
CTAACGTACGATCTACAATATATCACCGAGCCGGGGAAATTCGATGAGGTAGTAGAACAA
GATGGCGTTAAAATTGTCATCGATTCAAAGGCGTTATTCAGCATCATTGGAAGTGAAATG
GACTGGATCGACGACAAGTTGGCCTCTAAGTTTGTCTTCAAGAATCCAAACTCCAAGGGC
ACATGCGGTTGTGGCGAGAGTTTCATGGTTTAA
Promoter Sequence
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>ISA1 YLL027W
TGCTTCCCATTGTTTGCAGGATATATGTTCCGTGGCATGGGTATCGGTTGGGCTGGTTTG
TTATTAGGTCTATTTGCCGCTGCGATGATTCCCGTGCCTTTACTATTCTTAAAATATGGT
GAATCTATCAGAAAGAAATCCAAGTATGCTTACGCCGCTTAAGAAAAAGAAAAGCAGAAA
TCATGCTCTTTCTATATTTGCATTTTTTTATTTCATTGTTATTACTCACCCTGCCCCACG
CTCAAAGGGCTCGATAACGACATAGCATTATAGACACTGTGCAGCGTAAAGCTGACATAT
AAAGAAATTACAAAAAAAAATTAAAAAAAAAAAAAAAAACAATCAAAAAAGACACACAAC
TACAGAACAAAGGAAATCTTTTTCTATGCACAAGCACAAGAGTACTTAGAGAGTAGTGAT
ATCCCCTTTTTTTTCTACTATTTTTTTTTTTCCCATTTTTTTCCTCCAAGACTCCTCTTA
TGTGGTTGTTATGTATAGCCCATAGTTACTAAATAAAACACTAATTAATGATTAATAATC
CCTCTCTAATAAGAAATAGATAAAAGCTATTGTTCTTCTCATCGCCGGTTCTCGGCGTTG
TCCGTACCCTTGGCCGAAACTCGGGCGGGGGCTTATTAGTCATACCCTCAGATTTCATTG
GTCAGATAACAGTCACCCGGTAAATGCCCGTTTAATGACTTCTTTATTTTGGATTAAAAT
TGACAGGGAATTTCAACGGAATAAAGGAAAGAGATTGAGATGCTTTTAATTCATAAAGGA
AAGGGAAAGAGGACAGGAAAGCAAGGAAGAGTAATGGAATTTTGCAAATATTTGTAAATC
CTTTAGAATTACTAAGAAACTGTTATTTATTGACATTATTTTACTCGTCTTATTTATTTA
TTTATACATTTGGCCACCATTTTTGCACTCGTACGAAAGACCATTTTAGATTTTTTTGAT
TTGGTAGTATAACAAACGATCGGAACAATAACGTAACATA
Chr coordinates
Chr XII from 87403-88155