Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
TPO1
Systematic Name
YLL028W
Strain
S288c
Description
Polyamine transporter of the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; recognizes spermine, putrescine, and spermidine; catalyzes uptake of polyamines at alkaline pH and excretion at acidic pH; during oxidative stress exports spermine, spermidine from the cell, which controls timing of expression of stress-responsive genes; phosphorylation enhances activity and sorting to the plasma membrane
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>TPO1 YLL028W
ATGTCGGATCATTCTCCCATTTCTAATAAGGAAAATCATCTGCTGCCATCAGACTCGTCA
AGAAGCTCATCCAGCGATATGCATTCGACGGGCACCACGGGAACCACAGGCGTCGAACCT
GTAGATTTCACCGGTGAAGGTGCCAAATACACAACTGCTACGGAGGGCAATGGTGGTGCA
GATTTAGCGATTCAAAGAACGACGACTATGAATTCTGCTGCAGAATCAGAGGTTAATATC
ACGAGAAGATTAACTAAAATCCTTACTGGGTCTGTTAACGAGCCTGACCGTGTAGAGGTT
GATTATACCAATTGTGCGCCCATGGGTGGTGACAGACCTTACCCTCCATCGTTGCCGAGC
AGAGACCTGTACGAGGTTACTTTTGATGGTCCTAACGACCCACTACATCCATTTAACTGG
CCCATGAAGAAGAAAGTGCTGCTATGTCTGGTCTTATGTCTGGATTCTATTGCCATTGCT
ATGTGTTCTTCCATTTTTGCCTCTGCAGTGCCGCAAATCTGCGAGATATACCACGTCATC
GAAGTTGTCGCCATTTTGGGTATCACGCTTTTTGTTCTTGGGTTTGCGGCCTCACCGGTT
ATCTATGCTCCTCTTTCTGAATTGTACGGTAGAAAGGGTGTTCTGGTTTTATCTGCGTTT
GGATTTGCCCTTTTCCAATTTGCTGTCGCTACTGCTGAGAACCTGCAAACTATTTTCATA
TGTAGATTCTTTGGTGGTTTTATCGGGGCAGCACCCATGGCCGTCGTCCCCGCCGCGTTT
GCCGACATGTTTGATACTAATGTTAGAGGTAAAGCCATTGCGCTATTTTCTCTAGGTGTT
TTTGTAGGCCCCATTTTATCGCCTGTCATGGGTTCTTATATCGCACAAAGAACTACCTGG
AGATGGTTAGAATATGTTGTCGGTTGTTTCGCTTCCGCAGTTTTCGTTGCCATCGTATTG
TTCTTTGAAGAAACACATCACCCTACCATTTTGGTTAACAAGGCCAAACAGATGAGAAAG
CAAAGTAATAACTGGGGTATTCATGCTGCTCATGAAGACGTGGAGCTATCCATCAAAGAC
ATTGTCCAAAAAACTGTGACGAGGCCTATCATTATGCTTTTCGTGGAACCATTGCTACTA
TTCGTGACTATTTACAACTCTTTTGTCTACGGTATCTTGTATTTGTTACTGGAAGCCTAC
CCACTTGTCTTTGTGGAGGGTTATGGGTTTACTGAAAACGGTGAGTTGCCATACATCGCC
TTGATTATCGGTATGATGGTGTGTGCTGCTTTCATTTGGTATATGGACAACGATTATTTG
AAAAGATGTAGAGCCAAGGGGAAATTAGTGCCCGAGGCCAGATTGTACGCAATGGTCATT
GCAGGTACCGTTTTCCCTATTGGTATCTTATGGTTCTGTTGGACGGGCTACTATCCTCAC
AAGATTCATTGGATGGTCCCCACAGTAGGAGGGGCCTTCATCGGGTTCGGTTTAATGGGT
ATTTTCTTGCCATGTTTAAACTATATCATTGAATCGTATCTATTGTTGGCAGCTTCTGCC
GTCGCAGCAAACACTTTCATGAGGTCTGCATTTGGTGCATGCTTCCCATTGTTTGCAGGA
TATATGTTCCGTGGCATGGGTATCGGTTGGGCTGGTTTGTTATTAGGTCTATTTGCCGCT
GCGATGATTCCCGTGCCTTTACTATTCTTAAAATATGGTGAATCTATCAGAAAGAAATCC
AAGTATGCTTACGCCGCTTAA
Promoter Sequence
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>TPO1 YLL028W
CAATAATGACTAAAAGGTGAAAATTGAAAACATTACCTTCATTTTTTTACGGCCGGAGAG
GGGTAGGTACACTTAACCCCGAGCGCTTTTAGTGCCAAAAAGAGTTAATGTGCGTAGTCG
GATTTTAAACGACCATGCATGTACAGCCCCCTAGTGATTTATACTGATGCCTCATCAAGA
AATTTTTTCATCCAGGGTCCCTGCTCGGCGAACCTTTCCGCAAGAGTCACAAAAATCAAT
CTTATAACCAGGCACCAGTAGTACTGCCAAGCTTGGACTACATAGCCAACGTAAAGACAA
GGAGTCTGATTTAGTATTTCTTTTTTGCCAGCCAGTATTTTCTGCGCAGGATAGATTATT
TTAAGAGCCGAGAATTCCTTATGCGGGCCCGGTCACAACGGATTATAGGTTCCGCCAGAC
CCCGTTGCTTTGGTTCCATGGAGCAGGAGCAGGATTTTCCGTGGAAAGAGAAGCACCGAG
CGAAAAGCGGATACGGAAGGCGGATGCGGAAACGGATGCGGACGCGGAAGGAAGGAAGGA
AGCAAACCCTTCCGTCTATGTCGCTATGAAGCCGTCTCACAGTAGAGCCATTCGAGATTT
CCGTCCGTCGGTACACAGAAATCTTCGTATCGGGAGTTTTACTTTAAAAGGAAACGATCG
TAGGAATTCCCTAAAGAAAAAGGAAGAAAAATTTAACGTTGAACATTGTCATTTTCTTTT
TTTTTTTTATGTGTGCAGAATATACTATCAAGTAATGTGTTCTATATATAAAGGGTACCT
CATTTGATCTTGATGTTTCTTTCTGCTCGTATGCCTTGAGTCACCAGTTTTCAAAAATAA
TCTTGGTCTATAGAAGAGAAAAATCCAATAATCTGAAATTGGTTCTTCGCACCCTTGCAA
CGAGATCATATACTAAATATCGGGAACTCTTTATTTCTGGATCTTTTATCAGTCACTTTT
TTTTTTAGTCAAAGAAGCAAGAGAAAACTAGACAGAGACA
Chr coordinates
Chr XII from 84804-86564