Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
RPL8B
Systematic Name
YLL045C
Alias
eL8, KRB1, L4B, L8B, L8e, rp6, SCL41, YL5
Strain
S288c
Description
Ribosomal 60S subunit protein L8B; required for processing of 27SA3 pre-rRNA to 27SB pre-rRNA during assembly of large ribosomal subunit; depletion leads to a turnover of pre-rRNA; L8 binds to Domain I of 25S and 5.8 S rRNAs; mutation results in decreased amounts of free 60S subunits; homologous to mammalian ribosomal protein L7A, no bacterial homolog; RPL8B has a paralog, RPL8A, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>RPL8B YLL045C
ATGGCTCCAGGTAAGAAAGTTGCTCCAGCTCCATTCGGTGCTAAGTCCACTAAGTCTAAC
AAGGCTAAGAACCCATTGACTCACTCTACTCCAAAGAACTTCGGTATTGGCCAAGCTGTC
CAACCAAAGAGAAACTTGTCCAGATACGTCAAATGGCCAGAATATGTCAGATTGCAAAGA
CAAAAGAAGATCTTGTCCATCAGATTGAAGGTTCCTCCAACCATTGCTCAATTCCAATAC
ACTTTGGACAGAAACACCGCTGCTGAAACCTTCAAGTTGTTCAACAAGTACAGACCAGAA
ACCGCTGCTGAAAAGAAGGAAAGATTGACCAAGGAAGCTGCCGCTATCGCTGAAGGTAAG
TCTAAGCAAGACGCTTCTCCAAAGCCATACGCTGTTAAGTACGGTTTGAACCATGTTGTC
TCTTTGATTGAAAACAAGAAGGCCAAGTTGGTTTTGATTGCTAACGACGTCGACCCAATT
GAATTGGTTGTTTTCCTACCAGCTTTGTGTAAGAAGATGGGTGTTCCATACGCCATTATC
AAGGGTAAGGCTAGATTGGGTACTTTGGTTAACCAAAAGACTTCTGCTGTTGCCGCTTTG
ACCGAAGTCAGAGCCGAAGACGAAGCTGCTTTGGCTAAGTTGGTTTCCACCATTGACGCT
AACTTCGCTGACAAATACGATGAAGTCAAGAAGCACTGGGGCGGTGGTATCCTTGGTAAC
AAGGCTCAAGCTAAGATGGACAAGAGAGCTAAGACTTCCGACTCCGCTTAA
Promoter Sequence
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>RPL8B YLL045C
AAACATCTCTGAAGCATTTTAACATATATGGATCCGTCTTTCTTTCTTCTGCTAAGGGAC
GGTATTACACGACATATATTGTCAAGCGCAACAGAACTAATTGACTTTAGGACGAGAATA
ATATAACTTTATGACACTCTGCTCTCCTACTACTTCTTATGCCGTAACTCTCTCCGTCCC
TCAGTCCGTTGCTGCCTTTTTCTTGCGATGGAAGGCCCGTATCAGAATGCCCTTGACAAT
GTTCTCATGATAATGTAAGTATTCCTTCCTAAATAAAAGCATCAGCCGCGTTATCCCGCT
ACCGGGTTTTATTGTTTACGGAGAAAGCAATAACAGCATTTTTTTTGGTGTTCTTCGACT
ATCAACAAATAACCGCCGAAGCGCCTTGCGGAGGATAACCACCAACGAACTCAAATACCT
ACCGCGTACCTTCCTACGGTTATGTACTTTTGCACTGCTATTGCTTTGAGATGCTATGAG
AACTGCCGTCAAAATTGGGTGGCAAAGAGGGATAGCTTCACTGCCAATCACTACACTCTG
TTCTGAAGGAGGGGAATTACTGTTGTCTCATAAAAAAACACCTTTGAAACACTTTCACTC
ATAGAGAAGCCAAGAACTCTGATGAGTTCTTTATTTGTTGCCGCTAACTTTATCTTATCT
TCTCCATTGTAATAATTACTATTCTTTTTACTTGCCTGTTTTCCATCCCAATGAAGATCC
GTACATCTTAGACACCCTTTTCTTTTTTTCTTTTTTTTTTTTTTTTTTTTTTTTGGCTTC
CGAAGTGCCGACAACTAAAGAATTATCGCATTTTTTTTGAATACATCATACTATACGATA
GAACGCATTGAAACTTTTCCCATCTCAAAATCCAGGGACAATAGTATGGGATCGATATTA
TTATCAAGACATAAGTATTGTGATGCGCACGTTGAAATTCACTATTTTTTTTTTTTATAT
CTGTTTTTCAATACAGTGAACACGATAACTGAAAGAAAAG
Chr coordinates
Chr XII from 48629-47859