Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name RPL8B
Systematic Name YLL045C
Alias eL8, KRB1, L4B, L8B, L8e, rp6, SCL41, YL5
Strain S288c
Description Ribosomal 60S subunit protein L8B; required for processing of 27SA3 pre-rRNA to 27SB pre-rRNA during assembly of large ribosomal subunit; depletion leads to a turnover of pre-rRNA; L8 binds to Domain I of 25S and 5.8 S rRNAs; mutation results in decreased amounts of free 60S subunits; homologous to mammalian ribosomal protein L7A, no bacterial homolog; RPL8B has a paralog, RPL8A, that arose from the whole genome duplication
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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>RPL8B YLL045C
ATGGCTCCAGGTAAGAAAGTTGCTCCAGCTCCATTCGGTGCTAAGTCCACTAAGTCTAAC
AAGGCTAAGAACCCATTGACTCACTCTACTCCAAAGAACTTCGGTATTGGCCAAGCTGTC
CAACCAAAGAGAAACTTGTCCAGATACGTCAAATGGCCAGAATATGTCAGATTGCAAAGA
CAAAAGAAGATCTTGTCCATCAGATTGAAGGTTCCTCCAACCATTGCTCAATTCCAATAC
ACTTTGGACAGAAACACCGCTGCTGAAACCTTCAAGTTGTTCAACAAGTACAGACCAGAA
ACCGCTGCTGAAAAGAAGGAAAGATTGACCAAGGAAGCTGCCGCTATCGCTGAAGGTAAG
TCTAAGCAAGACGCTTCTCCAAAGCCATACGCTGTTAAGTACGGTTTGAACCATGTTGTC
TCTTTGATTGAAAACAAGAAGGCCAAGTTGGTTTTGATTGCTAACGACGTCGACCCAATT
GAATTGGTTGTTTTCCTACCAGCTTTGTGTAAGAAGATGGGTGTTCCATACGCCATTATC
AAGGGTAAGGCTAGATTGGGTACTTTGGTTAACCAAAAGACTTCTGCTGTTGCCGCTTTG
ACCGAAGTCAGAGCCGAAGACGAAGCTGCTTTGGCTAAGTTGGTTTCCACCATTGACGCT
AACTTCGCTGACAAATACGATGAAGTCAAGAAGCACTGGGGCGGTGGTATCCTTGGTAAC
AAGGCTCAAGCTAAGATGGACAAGAGAGCTAAGACTTCCGACTCCGCTTAA
Promoter Sequence
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>RPL8B YLL045C
AAACATCTCTGAAGCATTTTAACATATATGGATCCGTCTTTCTTTCTTCTGCTAAGGGAC
GGTATTACACGACATATATTGTCAAGCGCAACAGAACTAATTGACTTTAGGACGAGAATA
ATATAACTTTATGACACTCTGCTCTCCTACTACTTCTTATGCCGTAACTCTCTCCGTCCC
TCAGTCCGTTGCTGCCTTTTTCTTGCGATGGAAGGCCCGTATCAGAATGCCCTTGACAAT
GTTCTCATGATAATGTAAGTATTCCTTCCTAAATAAAAGCATCAGCCGCGTTATCCCGCT
ACCGGGTTTTATTGTTTACGGAGAAAGCAATAACAGCATTTTTTTTGGTGTTCTTCGACT
ATCAACAAATAACCGCCGAAGCGCCTTGCGGAGGATAACCACCAACGAACTCAAATACCT
ACCGCGTACCTTCCTACGGTTATGTACTTTTGCACTGCTATTGCTTTGAGATGCTATGAG
AACTGCCGTCAAAATTGGGTGGCAAAGAGGGATAGCTTCACTGCCAATCACTACACTCTG
TTCTGAAGGAGGGGAATTACTGTTGTCTCATAAAAAAACACCTTTGAAACACTTTCACTC
ATAGAGAAGCCAAGAACTCTGATGAGTTCTTTATTTGTTGCCGCTAACTTTATCTTATCT
TCTCCATTGTAATAATTACTATTCTTTTTACTTGCCTGTTTTCCATCCCAATGAAGATCC
GTACATCTTAGACACCCTTTTCTTTTTTTCTTTTTTTTTTTTTTTTTTTTTTTTGGCTTC
CGAAGTGCCGACAACTAAAGAATTATCGCATTTTTTTTGAATACATCATACTATACGATA
GAACGCATTGAAACTTTTCCCATCTCAAAATCCAGGGACAATAGTATGGGATCGATATTA
TTATCAAGACATAAGTATTGTGATGCGCACGTTGAAATTCACTATTTTTTTTTTTTATAT
CTGTTTTTCAATACAGTGAACACGATAACTGAAAGAAAAG
Chr coordinates Chr XII from 48629-47859
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