Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
CDC45 Systematic Name
YLR103C Alias
SLD4 Strain
S288c Description
DNA replication initiation factor; recruited to MCM pre-RC complexes at replication origins; promotes release of MCM from Mcm10p, recruits elongation machinery; binds tightly to ssDNA, which disrupts interaction with the MCM helicase and stalls it during replication stress; mutants in human homolog may cause velocardiofacial and DiGeorge syndromes External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA Hide Seq
>CDC45 YLR103C
ATGTATTATGGAATCAGCCAGTTTAGCGAAGCCTACAACAAAATCTTAAGGAATTCATCG
TCTCATTCATCATGTCAATTGGTCATTTTCGTTTCTTGTCTTAACATCGATGCGCTGTGT
GCGACGAAGATGTTGTCACTATTATTCAAAAAACAATTGGTACAATCTCAAATAGTACCG
ATATTTGGGTACTCTGAATTACGACGCCACTATTCTCAATTGGATGACAATATAAATAGT
CTGCTATTAGTAGGGTTTGGAGGCGTTATTGATCTGGAGGCTTTCTTAGAAATCGATCCC
CAAGAGTATGTTATCGATACAGATGAAAAGTCGGGGGAACAAAGTTTCAGGAGAGACATC
TACGTGTTGGATGCTCATAGACCGTGGAATCTCGACAATATATTTGGATCACAAATCATC
CAATGTTTTGACGACGGTACGGTGGATGACACATTAGGCGAACAAAAAGAAGCATACTAT
AAATTGCTTGAACTGGACGAGGAGAGTGGTGACGATGAGCTCTCAGGTGACGAGAACGAT
AATAATGGGGGTGACGATGAGGCAACTGATGCCGATGAAGTCACAGACGAGGACGAAGAA
GACGAAGATGAGACAATATCTAATAAAAGAGGTAATTCTTCAATAGGACCGAATGATCTC
TCAAAAAGAAAGCAACGAAAGAAGCAAATCCATGAATATGAAGGTGTTTTGGAGGAATAC
TATTCTCAAGGCACAACAGTGGTTAACTCGATATCTGCACAAATCTATTCATTATTGTCT
GCTATCGGAGAAACAAATCTTTCAAACCTGTGGTTGAATATACTTGGTACGACCTCGTTA
GATATAGCATATGCTCAAGTTTACAATCGATTATACCCCTTATTGCAAGATGAAGTGAAG
CGTCTCACACCAAGCAGTAGAAACTCAGTAAAGACCCCTGATACATTGACGTTAAACATC
CAACCGGATTACTACCTTTTCTTACTGAGGCATTCTTCATTGTACGACAGTTTTTATTAT
TCTAACTATGTCAATGCCAAACTATCCCTATGGAATGAAAATGGGAAAAAGAGATTGCAT
AAGATGTTTGCTAGAATGGGTATACCATTAAGTACTGCACAAGAAACATGGTTATACATG
GATCATTCTATTAAGAGAGAACTTGGGATAATATTTGACAAAAATTTGGATCGTTATGGG
TTGCAAGATATAATTAGAGATGGGTTTGTTAGAACTCTTGGATATCGTGGGTCCATAAGT
GCCAGTGAATTTGTCGAAGCACTAACAGCTCTTTTGGAAGTAGGTAATTCAACTGATAAG
GATAGTGTGAAAATAAATAATGACAATAATGACGATACAGATGGAGAGGAAGAAGAAGAT
AACAGCGCTCAAAAATTGACGAATTTGAGAAAAAGATGGGTTTCGAATTTTTGGCTCAGT
TGGGATGCTCTAGATGACAGAAAGGTGGAACTATTAAACCGTGGCATTCAACTAGCACAA
GACTTACAGAGAGCAATTTTTAATACCGGGGTTGCTATATTGGAGAAGAAATTAATCAAG
CATTTAAGAATTTATAGATTATGCGTCTTACAAGACGGACCCGATTTAGACTTGTACAGA
AACCCATTGACGTTATTAAGATTAGGAAATTGGCTCATAGAATGCTGTGCGGAATCTGAA
GACAAGCAATTGTTGCCCATGGTGCTTGCCAGCATAGATGAAAATACGGACACTTACTTG
GTTGCTGGGTTAACACCTAGGTATCCTCGCGGACTAGACACGATACACACAAAAAAACCT
ATTTTGAATAATTTCAGCATGGCGTTTCAACAAATAACTGCAGAAACGGATGCTAAAGTG
AGAATAGATAATTTTGAAAGTTCCATAATTGAAATACGTCGTGAAGATCTTTCACCATTC
CTGGAGAAGCTGACCTTGAGTGGATTGTTATAA Promoter Sequence
Download FASTA
>CDC45 YLR103C
CCTAAACCCCTTGTTCTTTGCTTTGGGGCCCTTGACAGGGTCATCATATATTGCTCTAAA
CTTTTCATTGTGTGTGGCTGGTTTGGATATGCAAACAAATTTATTATCAGGAAGGACACA
TTTCAACTGAGATTTAGGGAAGGGACAAGGACAGTCTTTCTGCTGTGCAACGCACGTTAG
GGTGTCCGGACACAAATACCCATCACAAGGGTTATTTAAAACTTGATCTTCATATGATTG
TTGCTGTTGCTGTTGCTGTTGCTGATGATGACCGAAATTGAAGAAGGCATTCACTCCAGT
GCTGCCAAAAATAAACAATGCAAAGATGAGAACGATACTCCAGCGACTTTGACTCATACT
ACAGTAAAATTTGGTCGTTTTTTGCCTGGCAAACCATGCCTATTTTTCGTCATTAAAGGT
CTTCTGAGCTTTCATCAAAATTATCTCTATAATTATAAAGGACAGCTCAGAGCCACACCC
AAACATCTGCAAAGGTAAAGGCCATCTTTCATCTCACATTGCCTAACAAGAAAGTCACAT
TGCAATTGTTTCGAGAAGAAAACATTAATTCAATTACGTGGTTCCCATGCGTCTGTGTTA
AGCGTCAATTTATCATTTGACGAACTCGTTGCAACCACAAACAAAGCAAGGGCCGCATTT
ATCAAAGGAAAACCAACCAAAAGCATAAATAAACGAGATTTTTATTATGAAAAAGCCATG
CGAATCCTACTAGAATAAATTCAAAGTGAAGACATTTAGTCAATTCGATCTTCTCTCTCT
TGCTTTAACTAGTCGTAAAACCTAATAAGTTTCATTCACGACGCGTATTTTTTTTTCAAC
ATATCATCTAACGCGTTTTAAGAAATTTCAGTAAATAATGAAGCTGTAGTAATGCCAACA
ATCCATTGTGGCTACTTTATACAACGCACTATAGAGCAATAAAAGTGTAGCAATAAACAC
TAGAGAGAAGGCACATAATAACAAGAATATACTCTCGCAC
Chr coordinates
Chr XII from 345941-343989
