Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
SLX4
Systematic Name
YLR135W
Strain
S288c
Description
Endonuclease involved in processing DNA; acts during recombination, repair; promotes template switching during break-induced replication (BIR), causing non-reciprocal translocations (NRTs); cleaves branched structures in complex with Slx1p; involved in interstrand cross-link repair, Rad1p/Rad10p-dependent removal of 3'-nonhomologous tails during DSBR via single-strand annealing; relative distribution to nuclear foci increases upon DNA replication stress; FANCP-related factor
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>SLX4 YLR135W
ATGGAACTTCAGAGGGCACAACGGAATTTGAAGTTTTTACAAAACGAGGATTATGTGAAC
GTTACCGATCAAACTAACCTGAATGGAGAGAGCCAGAATGCTTACTCTTTAGGAATGGAA
ACTCAAGTACCGGAAATGCAGTTTTCCTTATCATCTGATGATGATTCAATAGGTACGCAA
GTAAAAAGCGTAACTGCACAAAAATCGCCTATGACGCAAGAGACTACGAAAAACGATACA
GAAAGAAATAAAGATGTTGATAAAAGTTGTAACCCAGTCAGCACTTCCCATCCCGATTTA
GGCGGATCAAATATCGAGGAGAACATATTCATTAACACTCAAATTCAAAGCCGACTTGAT
GACGCAGAGGAAGAAACAAATCTTAAGTTAAAACTTGAAAAATTCAAGTATTCGTTCAAG
AGTAGTAACGCAGATGATACCCACAGCAATGCAAATGTAACAGCTAAAAGAAGACCAGCA
ATAAGGAAGGCTAATTCGAAACTCAAAACAAAACCTAAAACTAAACGAGACCCTAAAATT
ATCAAAAATATAACTGATTTCAATATTAATAACTACGAACGTTCAAGGACTGCCAGCTTA
TTAAAGCAATTATCAGGTAAGCACAAGAAGGTTTTGGACATAATAAAGACGCAAAATGAA
GGAAACAGTGATAAACCTCCCAGAGCAAGGAATAACAAGGGTGAAAAAGCTACTTTTGAT
ACATATAGTGAACAGGAGTGGAAAGATATTATGAAACTTCTTCTACAAAAGTTTCCGCAA
AGTGAGGAAACGGATTTGAATGAAGTCCAGAAATTTTTATATGGAAGCGAAAAAAGCTCG
AATTCTCTAGACAATCAAGAATCCTCACAACAAAGACTTTGGACAGCATCACAATTACCA
CCCGAGCTTCCCGATGAGGCTATTCAACCAGAGCAGGAAGAAAGGATACGCGATACCCAA
AGTGCAGTAAATTTCTTATCGTTGTCTCAAGTAATGGATGACAAAAGTGAAATTATGAAA
GACGAAGAAAGCATAATTATTTCACGGGGAGATTCTACAAGCTCTCAAGAATATGGAAAC
GGGTTAGAGCCACAACAACCGGTAGGAAATGTTGTTGGTGAAGATATTGAACTGGCTGTG
GGAACACGTATAAATGCATTTTCACTGACAGATTATAAAGCTTGCAAACCTATGTCTGTT
GAGGTAAGTAGAAGATGCGAAAACAGTACGGATAATGATTATGACAATATTTCTATTGTC
TCAGATACTACAGATGAGACATCCACATTGTTTCCACTAGACCAGTATCGGTATGTTTTC
ATTGAAAATGATGAAAGACCACCATTAGCCACCGACACGATAGGCAGCACACAGTTTTTC
ACTCCAAACACATCGCCTTTGGATGGGATAATCGATTTAACACAGGAATCATTCAAAGCT
GTTCGATCGTTAATATCACCTTTGAAAGTAGAAAACAACAAAACAGGGGTAACATCACAA
GCATCAAATCAGGTTCAGGTACCAGCTACAAGAACCCCTACAATTATTCCTCAAAAGAAC
CTTACTACAACTTTAAAAACTGAAGAAGAAAAGAATAACATAGGAAGTTCCATCAGAGTT
AAATTATTGCAAGAAAGCGTAGTTAAGCTAAACCCCAAACTGGTGAAACATAACTTTTAT
AGAGTTGAGGCAAATGATTCTGAAGAAGAGGAGACAGAATTTGATGACCAATTCTGCATT
GCTGATATCCAATTGGTAGATTCCTCCAAAATTTCGACTAAAGATTCTACACAAAATCCT
ACTACTAGCAACGACATTATTGATACCTCTGCAGCTAGTTCCATAGCTTCTCCCGAGAAA
TTTTGTGAGATCATGATGTCCCAATCAATGAAAGAGCTTCGACAAAGCTTGAAAACAGTG
GGGTTGAAACCTATGAGGACGAAGGTTGAAATCATTCAATCCTTACAAACTGCATCTCAA
ATTCTGTCCACAGCTAATCCAGATAATAAAGGTGAGCATGGTGGGGTGGCAAATTTCAGT
AAGATAGAAATATTTGATCATTTAACCGAACTAATTGAAGCCTTCCCTGATTTTTTGGAG
CGAATATATACCTTTGAACCCATTCCGCTAAATGAGCTAATTGAAAAGCTGTTCAGCGCC
GAGCCATTTGTTTCGCAAATCGACGAAATGACCATCAGAGAATGGGCCGATGTTCAAGGA
ATATGTCTGAGAAACGATAAAAAGTAG
Promoter Sequence
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>SLX4 YLR135W
AGTTGACTCAAGACAAGGACTTCCAAGACAACTCTAAGATTAGAATGATTGAAGTTATGT
TGCCAGTCTTTGATGCTCCACAAAACTTGGTTAAACAAGCTCAATTGACTGCCGCTACTA
ACGCTAAACAATAAGCTAATTAACATAAAACTCATGATTCAACGTTTGTGTATTTTTTTA
CTTTTGAAGGTTATAGATGTTTAGGTAAATAATTGGCATAGATATAGTTTTAGTATAATA
AATTTCTGATTTGGTTTAAAATATCAACTATTTTTTTTCACATATGTTCTTGTAATTACT
TTTCTGTCCTGTCTTCCAGGTTAAAGATTAGCTTCTAATATTTTAGGTGGTTTATTATTT
AATTTTATGCTGATTAATTTATTTACTTTCGTATTCGGTTTTGTACCTTTAGCTATGATC
TTAGCTAATTGAAGAGGGTGGTGTGATCTTTAACCATACCTTATTATCTTTCAGCTGCTT
ACCATTTTCTTATATTGATTTTTAGCGAAAGATTTTTATTCACAAGCTTTTTTTATCCTT
AATGCTCGAATACTACAACAAAACAAAAAACATTAAACAGTTTTTAATTTTGTGAACAAA
CTGAATTACAAGGCCTTACATCTTATTTAGAATATATTAAGAAACAGAGGCCAACATGCC
TTCTTAATTATATTGATATGGACCTCTGTCCTTCCTAAAAACGGGTTTTTGTTCGATGAA
AAATCACCAGTAGAGCACCATATATGAATTTACAATCATTGTAGGGAAAAGAAAACTTGT
TCTGCTTCGCCAATTGATTTCATTTCTTTTTTTCCTTTGTTTTTGTTGTATACTATTAAT
ATGCGTAGTTCTTTGTCACTTAGTGGTTTTTTGTTTAATTTATAACGCGAAAGCTGCATA
CTAAAAATATAGAGATGAATGGAACTCCGAACAAGCAAGAGAGATATTATCTATCTCTGT
TCCATAATAATAACCAGTAGTTCAGTTGGGGAACTTAATA
Chr coordinates
Chr XII from 413281-415527