Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
TIS11 Systematic Name
YLR136C Alias
CTH2 Strain
S288c Description
mRNA-binding protein expressed during iron starvation; binds to a sequence element in the 3'-untranslated regions of specific mRNAs to mediate their degradation; involved in iron homeostasis; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress; TIS11 has a paralog, CTH1, that arose from the whole genome duplication External sources
Open in SGD
Open in KEGG
Gene Sequence
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>TIS11 YLR136C
ATGTGGGCTCAATTATCATATACTAGACCAGAATCTCAGAAGACTGACTTAACGTCGTTG
TTTTCCACAGATCAAGAGCAAAATCCATTAAATGACTACCAGTACCAGATCAATATTAGG
GAACTGGAGGAGTATTACAACAAGACGATTTTAAACGAGGATAACATACAGGAAACAAGC
AGTGAAATATCTTCGGCAGTTTCATTCTCTCCACCAAAAAATACAAACGCTATTCAACCG
GGGCTACTGTATGATCCACAGTTAATGAACCCTTTTCTCCCATCCGCTCACCTGAATAGC
ACGGCACCTACTACTTTTAAAAAGAAACTAGAGGTACAAATAAATCCGGACTATGTCCCA
AAATCTTCACAATTACCATTAACTTCACAGAATTTGCAACAGTTGTCTCAACAAAAGCCC
AAAAATGATGCTTCTTTTTCATCAGAGAAGGAATCCTCAGCTCAACCTAAGGTGAAAAGC
CAAGTGCAGGAAACTCCCAAACAATTATACAAGACAGAGCTGTGCGAATCATTCACTTTA
AAAGGAAGTTGCCCTTATGGCAGTAAGTGTCAGTTTGCTCACGGACTCGGCGAATTAAAG
GTTAAGAAATCGTGCAAGAATTTCAGGACGAAGCCCTGTGTGAATTGGGAGAAACTAGGT
TATTGTCCTTATGGCAGAAGATGCTGCTTCAAACATGGCGACGACAACGACATTGCTGTT
TACGTGAAAGCTGGTACTTACTGTAACGTCTCTTCGACTAGCAAACAATCAGACGAAAAG
AGAAGCAATGGTCGCGGCTCCGCCAAGAAGAAGAATCTAAATGTTAAAGTAAAGGCTTTG
CAGAGAATGACCTGGTGA Promoter Sequence
Download FASTA
>TIS11 YLR136C
GAAATGCACCGCTTTCTGGTCAACTGTGATAAGTTTTCCATGATGTTATCTTTTAATTTA
TTAAGAATGCCCTTCTGATCTGTCGACACGTAGGTGTCGACGAAGTTACCAAGAATCACG
GGCAAAATACCTGATATTCCTGCTCCAAGTTCCAAGATACCTCTCTTGCCGCGATCAGCG
CCCGTGAGGTCGACCAGCCTGGGCAACTCAAGCTTGTGCCCCTCGCAAGAAGACCCGCAG
GTTACTTCCACCTGACTCCCAAGACGGAAAGGTGCAGCGCTAGTACTATACAGCAGCCAG
TTGATGAAGAAAGGTGTGGTAGACCACAAAACGTATCCTGTGGTGGAGTTTCCGTTGTCT
CTGGACGAGCGCAAGCTTGATATGGACTGCCCCACGCTAACATGATAGCTATCCACAGCA
ACATTCTGATCTTCTTCAACACTACTAGCCTTATTTCTTCTTCTCACTCGCTTTTTTTTT
CTGCCGCCTTCCAGCCCAGAGGGTTCAAACGTTATCTCTAGCACACCGCCCCTTCTATCC
TGAATACCCAAATCCTGCGCCAGTTTCCCGGACTGGCCCTCCAATTGTGTGTACCGTTCG
AACACGTGCTCGTATATTGTTTCCTCATCCAGTAGCCATAACTTGAATGCCATTCTGCCT
AGCCCATTTGCGTCTTCGCTGCCGTAACCATTCTCTCTTCTTGACAGCACTGCCTTGGTC
AGTTCTCTATATTTGTCGCGCCGCCGCAAAATGCACCCACATTAAAGAAGACGACGCCAA
TCGACACCCTAATTTGGAGGTGTAGATGCACAATGGCACATGCAGTTGGGTGCATTGTGC
CAGCAATCTCGTCTCGATTTCTCTACATGTAACTTGTATATATATTTGAGAGAAGACATA
ATCGTTGGTGGGACTTGGAGGCTCTTGGTAGGTCGTATTTGTGCATCTTGAGAGAAAGCG
AAACAGTGCTGCAAACTCAATACGTAAAAAATAACGCAAT
Chr coordinates
Chr XII from 416658-415801
