Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
TOS4
Systematic Name
YLR183C
Strain
S288c
Description
Putative transcription factor, contains Forkhead Associated domain; binds chromatin; involved in expression homeostasis, buffering of mRNA synthesis rate against gene dosage changes during S phase; target of SBF transcription factor; expression is periodic and peaks in G1; involved in DNA replication checkpoint response; interacts with Rpd3 and Set3 histone deacetylase complexes; APCC(Cdh1) substrate; relative distribution to nucleus increases upon DNA replication stress
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>TOS4 YLR183C
ATGAGCTCGCAATTTCCTTCGTCCCCCTACAGGACAGTGGATCCGTACTCTCCACCAAAT
TACAAACAGCAGCCTAATTGTCCCTCATCCAATTATGAGAAAGCTGGTAAAACTGCGTCA
GAATCAATTGGAAATTTCGGGAAAGGAGATTATCCAACTCCATTTCCTTCTTCCAGTATA
GGAAGGGTTTCGTCTCCCGTTAGGTCGAATAAGGTTGACGCCATCCCTTCCTCTCCAGCT
TTTCCTGGCCAGTTGGCAGAAACGTCACCCAAGTTTTCTTCCAAACTTTCTTCTCCTTCA
AGGCATACTAGAGTCATCAATGCTGAACTAGATCCTAGCAAGATCAGCACCATTACTGTA
GGGCGCAATAGTTCGCAATGTGATGTTGCGCTCTGTAAGAATAAGTTCATATCCAGAGTA
CACGCTAGTATAACTTATTTACCACAAACAAATGAAGTGAAGATTCACTGCTTCAGTATG
AACGGATTAATCGTTACCTATCGTAAGCAATTTGATTGTTATCAATTAAAGGATACCATG
AATAACAATAATAGGGCATATAGGCTTGTTCCCAGATTCTCTAACGAAAAATGTGTTAAA
GAAATTCAAGACGAGGGAGGATTCATTAATTTCACTCTGGAAGAGGGAGACACCGTTTAT
ATGACATATTACAAGGGTATCATGTTGGATTTTAGGCAGGTTTTACTTCGCATTTCGTTA
AAAGAAAAAAACTCTTCTTCAGAGCCGTTAAGATTCGAGAAGAAAGCTGAATTTGAAAGT
GAAAGTGAAACGAAACATATGGGTAGTATAAGGAAGCATCCATTGATTTTTACTGACACT
TCGATGGACAGACCCAAAAAAATACTTAAGGATAGCAACAAAATCTCAATTGGTAGTGAT
TCTGGCGTTGCAGAAAGGATGCTAAACCACTTCCTAAATTCTAAATCGTCCCCACTTTCA
TCCGTCTCCTCTGTTGATCACGAGGAACAAACCCTGAGACAAGATTCACTATCATCTGAT
AAAAATCCTATGACTATGAAGAAACCAAAACTTAACAAGAGGGTCTTACCTTCAAAGCCA
AAAAAATCGGTGAAAGAGAATTTGGATGAGCTATCTAGAAGAAATATTGATGTTATGCAT
CTACAGCATATTTTAACCAATCACCTAGCTTTTGCAAACGTCCAGCAGACGCCATTATTC
CAATTACAGCAGGTGAACTCACAAATTTCTGAGCTTTCAAGAGATGAATTACGTTCGATT
TTGAGCGACGCGAAATGTGTCGGTGTCATTTACCGTCATGGTAAGGACGCCGCCGGCAAA
CCATTGGACGAAGAGTATTTCTACGATTTAGAAAACGATGATGATTACGAGAGAAGAAAC
TTGGTGAGTTCATTAAAAGGTGGAAGGACAGGCTTAAGATCTTGTAGAAGGACACATAAA
CAATATTTTTGGAAAAAGCCAGCAAAATAG
Promoter Sequence
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>TOS4 YLR183C
TCAAATTGTTGTGCAATTTGGTTAAGTTTGTTAGTACAATTTGCTTTATCTTATAGTTAC
ACTTTTTTCGTGACTGTTACAACGCCATTGAAATTGATCCTTTCGAGTTCCCTCAGGCAT
ACAAGCAGAATATTTCTTCTATACGGTAAATTTGTTGTCATGCGCATGTCTTTCGTTCAC
TATTCTGTCTTCATACAAGTATACCAGTCTCGTATCGTCCAGTCTTGCTAAGTATAAATT
TGGTGTGCATGCGTTCCGATATTTCTCTTCAGATAATCATAACATTTCTCCACGGTCGTC
AATAACAGGTTCACAGTTTTATTCTCAATGTCCTACTACATACTACCCATTTTTGTCTAT
ATTATTTGTATGAGGCTTTAGCAAATACCTCTTAAAAGTAAACATTTTTGAAATTTAATA
GTACCCTCATATAGAGCATTTCTCATTCTTACACTTGTAATATTGACGGTGATGAGAAAG
CTACCAGGAGAACATCAACGTTTGGAGGAGACAGACCGACGGACCACACTTCACCAGTAT
GGCATCGCCCTGCCTACCATCAGCCTAGAGAACGGGCAGACGGATTGACTTCCCTTTCCC
CAAGGGGCCGCCTTCTTGTTGCCGGCCTGCCGAAGTGTGTTTTAGAATTTCTTCGAAAGA
GAATAGTCTCGACAACGTTTTGTCTTGGAAAACCTTTTGTGTACGGATGTTTAGTTAATA
ATAATGTACAGATGTTAATATGGTTTTTTTTTTTTGATATGAAAACGCCAAAACGCGAAA
AAAAAATCCCGTGGCCCTTTTTTCTTAAGTTCATCTCTATGGTTTGCTTTCGTGTTTTGA
TGAGAATGAACAGCGGCAGTCGACGTAAACTAAAATTCATCAATGGAAACTCTTTCTCTA
CTTTCATTCATTTAGAATTGAATTATAGCAATCTACTTTACGTACAAAAGTCCATATACA
TCTGCCACGACACATCAAAGATTAATAATCACAAGAAGGC
Chr coordinates
Chr XII from 522012-520543