Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name EMG1
Systematic Name YLR186W
Alias NEP1
Strain S288c
Description Methyltransferase for rRNA; methylates pseudouridine 18S rRNA residue 1191; member of the SPOUT methyltransferase family; required for maturation of 18S rRNA and for 40S ribosomal subunit production independent of methyltransferase activity; forms homodimers; human ortholog is mutated in Bowen-Conradi syndrome, and equivalent yeast mutation affects Emg1p dimerization and localization but not methyltransferase activity; human EMG1 complements lethality of null and ts mutant
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>EMG1 YLR186W
CTAAAGCCTCATACAAATAATATAGACAAAAATGGGTAGTATGTAGTAGGACATTGAGAA
TAAAACTGTGAACCTGTTATTGACGACCGTGGAGAAATGTTATGATTATCTGAAGAGAAA
TATCGGAACGCATGCACACCAAATTTATACTTAGCAAGACTGGACGATACGAGACTGGTA
TACTTGTATGAAGACAGAATAGTGAACGAAAGACATGCGCATGACAACAAATTTACCGTA
TAGAAGAAATATTCTGCTTGTATGCCTGAGGGAACTCGAAAGGATCAATTTCAATGGCGT
TGTAACAGTCACGAAAAAAGTGTAACTATAAGATAAAGCAAATTGTACTAACAAACTTAA
CCAAATTGCACAACAATTTGATTTTCTTTTTAAATAGAGGGTACTCCTTCATTCGGTAAA
CGTCACAACAAGTCCCACACTTTGTGTAACAGATGTGGTCGTCGTTCTTTCCATGTTCAA
AAGAAGACCTGTTCCTCCTGTGGTTATCCAGCTGCTAAGACCAGATCTTACAACTGGGGT
GCCAAGGCTAAGAGAAGACACACTACTGGTACTGGTAGAATGAGATACTTGAAACACGTT
TCAAGAAGATTCAAGAACGGTTTCCAAACCGGCTCTGCTTCTAAGGCTTCTGCTTAATTT
TTATACTAAGATCTATTTCTTTAAATGAAAACTCAATAATTAGAGACCTTATATAATAAC
CAACTGCAAAAAAACTTCTAAACAATTAGTTAACAAATCTCCAGCCTTTTTTTAATATAT
CTTTATTCATATGTAACGCCTTTGAGTGCTTACGGGAAAAGTAGAATTGATAGTTTCGTA
ATTCATGACCGGAAAAAGTGAAAAATTATTGTTCGATGAATATATACAGAGATGTCTTGA
ACTGTTTTTGCCAGCATCATTCGTTATAGGGAGCAAAGTTAGTGCAACCCAGTTACCAGA
TATCTAGTCACCAAGAAGAAAACCCGTAAAATCGTAGGTC
Chr coordinates Chr XII from 523632-524390
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