Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
EMG1
Systematic Name
YLR186W
Alias
NEP1
Strain
S288c
Description
Methyltransferase for rRNA; methylates pseudouridine 18S rRNA residue 1191; member of the SPOUT methyltransferase family; required for maturation of 18S rRNA and for 40S ribosomal subunit production independent of methyltransferase activity; forms homodimers; human ortholog is mutated in Bowen-Conradi syndrome, and equivalent yeast mutation affects Emg1p dimerization and localization but not methyltransferase activity; human EMG1 complements lethality of null and ts mutant
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>EMG1 YLR186W
ATGGTCGAAGATTCCAGAGTTAGAGACGCCCTCAAAGGTGGTGATCAGAAGGCATTACCG
GCCTCTTTGGTTCCTCAAGCACCTCCTGTCTTGACATCAAAGGATAAGATTACTAAGCGG
ATGATTGTGGTATTAGCGATGGCATCCCTCGAGACACACAAGATATCGTCCAACGGGCCT
GGTGGTGACAAATATGTCCTTTTGAACTGTGACGACCATCAAGGTTTATTAAAAAAAATG
GGTAGAGACATTAGTGAAGCAAGACCTGATATTACCCACCAATGTCTTTTGACGTTGCTA
GATTCTCCAATCAACAAAGCCGGAAAGCTGCAGGTCTATATTCAAACAAGTCGAGGAATT
CTGATCGAGGTTAACCCCACTGTTCGTATACCAAGAACTTTCAAAAGATTTTCAGGTTTA
ATGGTTCAGTTACTACATAAGCTTTCTATCAGATCGGTAAATTCTGAAGAAAAGTTACTT
AAAGTCATTAAGAACCCAATTACCGATCACCTACCTACTAAGTGCCGTAAGGTGACATTA
TCCTTTGACGCACCAGTTATCCGCGTTCAAGATTACATCGAAAAACTAGACGATGATGAA
AGTATATGTGTCTTTGTTGGTGCCATGGCAAGAGGTAAAGATAACTTTGCGGATGAATAC
GTCGACGAAAAAGTCGGCTTGTCCAATTACCCATTGTCTGCCTCAGTTGCATGTTCTAAA
TTTTGCCATGGCGCTGAAGATGCTTGGAATATTTTATAG
Promoter Sequence
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>EMG1 YLR186W
CTAAAGCCTCATACAAATAATATAGACAAAAATGGGTAGTATGTAGTAGGACATTGAGAA
TAAAACTGTGAACCTGTTATTGACGACCGTGGAGAAATGTTATGATTATCTGAAGAGAAA
TATCGGAACGCATGCACACCAAATTTATACTTAGCAAGACTGGACGATACGAGACTGGTA
TACTTGTATGAAGACAGAATAGTGAACGAAAGACATGCGCATGACAACAAATTTACCGTA
TAGAAGAAATATTCTGCTTGTATGCCTGAGGGAACTCGAAAGGATCAATTTCAATGGCGT
TGTAACAGTCACGAAAAAAGTGTAACTATAAGATAAAGCAAATTGTACTAACAAACTTAA
CCAAATTGCACAACAATTTGATTTTCTTTTTAAATAGAGGGTACTCCTTCATTCGGTAAA
CGTCACAACAAGTCCCACACTTTGTGTAACAGATGTGGTCGTCGTTCTTTCCATGTTCAA
AAGAAGACCTGTTCCTCCTGTGGTTATCCAGCTGCTAAGACCAGATCTTACAACTGGGGT
GCCAAGGCTAAGAGAAGACACACTACTGGTACTGGTAGAATGAGATACTTGAAACACGTT
TCAAGAAGATTCAAGAACGGTTTCCAAACCGGCTCTGCTTCTAAGGCTTCTGCTTAATTT
TTATACTAAGATCTATTTCTTTAAATGAAAACTCAATAATTAGAGACCTTATATAATAAC
CAACTGCAAAAAAACTTCTAAACAATTAGTTAACAAATCTCCAGCCTTTTTTTAATATAT
CTTTATTCATATGTAACGCCTTTGAGTGCTTACGGGAAAAGTAGAATTGATAGTTTCGTA
ATTCATGACCGGAAAAAGTGAAAAATTATTGTTCGATGAATATATACAGAGATGTCTTGA
ACTGTTTTTGCCAGCATCATTCGTTATAGGGAGCAAAGTTAGTGCAACCCAGTTACCAGA
TATCTAGTCACCAAGAAGAAAACCCGTAAAATCGTAGGTC
Chr coordinates
Chr XII from 523632-524390