Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
HCR1
Systematic Name
YLR192C
Strain
S288c
Description
eIF3j component of translation initiation factor 3 (eIF3); dual function protein involved in translation initiation as a substoichiometric component (eIF3j) of eIF3; required for 20S pre-rRNA processing; required at post-transcriptional step for efficient retrotransposition; absence decreases Ty1 Gag:GFP protein levels; binds eIF3 subunits Rpg1p, Prt1p and 18S rRNA; eIF3 also involved in programmed stop codon read through; human homolog EIF3J can complement yeast hcr1 mutant
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>HCR1 YLR192C
ATGTCTTGGGACGACGAAGCTATCAATGGTTCTATGGGTAATGATGACGCCGTTTTGATG
GACTCATGGGATGCTGAAATTGGTGATGACGAACCTGTCATGCAATCATGGGATGCAGAA
GAGGAAGAAAAGAAGCCTGCCCCAAAGCCAAAAAAAGAACAACCAAAAAAGGTTAAAAAA
GGGAAAGAATCCTCCGCTGACAGAGCCCTATTGGATATTGACACATTGGATGAAAAGACA
CGTAAAGAATTAATCAAAAAGGCTGAAATGGAGTCTGACTTAAACAATGCTGCAGATTTG
TTTGCGGGTTTAGGTGTTGCCGAAGAACATCCAAGGGCTCGTGCTTTACAAAAGGAACAA
GAGGAACAAGCTCTAAAAAGACCCGCCTTTACCAAGGACACACCTATCGAAACACATCCT
TTGTTTAACGCCGAAACAAAGAGAGAGTACCAGGATTTAAGAAAGGCTCTTACTGCTGCT
ATTACACCAATGAACAAAAAATCTCCGCTGAACTACTCCTCATCGTTAGCGATTGATTTG
ATTAGAGATGTAGCAAAACCAATGTCCATCGAATCTATAAGACAAACAGTTGCTACTTTG
AACGTTTTGATCAAAGATAAGGAAAGAGAGGAGAGGCAAGCTCGTCTGGCCCGTGTTAGA
GGTGGTACTGCTACTGGGGGTGCTGGTAAGAAGAAAGTCAAAGGTAAGACCAATTTGGGT
GGCGCATTTAAGAAAGATCAAGATTTCGACCTAGATGGCCCCGACGATTTTGAATTCGGT
GATGACGACTTTATGTAA
Promoter Sequence
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>HCR1 YLR192C
AATAAGTATTGTCTGGCTTCTGAGACGGCGGTAAGATATCCTTAAGAGTTGCAATGGTCC
TTTTACACAAAAGCACACATATATTTCCTACCGATTTTGCCTCTGTTTCACGCGCCTTTT
TTAATAGATACCCCAATCCATACTCCCCCCATGTACTATCCATAGACACAATATCAAGGA
ACGTTGATCAAGAAGGAAATTTGCGCACAACGAGGCTGTTGAAAAAGTCCGGAAAGCTGC
CCACATGGGTCAAACCCTTTTTAAGAGGTATAACAGAAACATGGATAATCGAAGTTTCCG
TAGTGAACCCCGCTAACTCCACAATGAAAACTTACACTAGGAATCTGGATCACACTGGAA
TCATGAAGGTTGAAGAATATACTACCTATCAATTTGACAGTGCTACAAGTAGTACGATAG
CAGACAGCCGGGTGAAGTTTTCAAGTGGCTTCAATATGGGTATCAAATCTAAGGTAGAGG
ATTGGTCGCGCACTAAATTTGACGAAAACGTTAAGAAAAGCAGAATGGGCATGGCATTTG
TTATCCAAAAACTCGAAGAGGCGAGAAATCCTCAGTTTTGATGTTCCCATTTAAAGATCT
TTAAAGATATCACCATGGGCGAGCGAAATTGAGAAAACTAGTGCAGCTCGCATTTGGTCA
CGTCCTAAAAATTGTAAATAAGCGCTGGTTCAACAAAATTTAATATACACACATATATAA
TTATTTATTTATAACAGTCATTCTGCTAAACTATACATCAAATGTCACTAATCTTGATAT
TATGGTCGTCCCTGTATCATATTAGACGAACACACCTGTTTTTGGGCATTTTCCGAATTT
TTTTTTCATGCTAGCTAAGTCAGAAGTACTACATTAAAGAATTGAGAACTGACTGCTCCC
ACCATTCTTGAACTCTCGCTTTAAATTATCTTACTATCTTTTGAGTTCCTTGTAACTATT
CTATCCTAACCACCACCTCAAAAAAAAAAAAGTAATAAAA
Chr coordinates
Chr XII from 539589-538792