Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
ECM22
Systematic Name
YLR228C
Strain
S288c
Description
Sterol regulatory element binding protein; regulates transcription of sterol biosynthetic genes upon sterol depletion, after relocating from intracellular membranes to perinuclear foci; redundant activator of filamentation with UPC2, up-regulating the expression of genes involved in filamentous growth; contains Zn[2]-Cys[6] binuclear cluster; ECM22 has a paralog, UPC2, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>ECM22 YLR228C
ATGACATCCGATGATGGGAATGCTGGACAAGAAAGAGAGAAGGATGCTGAACTGATTGAG
GTTGGGGGCAAGAAAGTGAGCAAGACTTCGACAGGGAAACGGAAGTTTCATAACAAGTCC
AAGACCGGTTGCGACAATTGTAAAAGAAGAAGAGTAAAATGTGATGAAGGCAAACCATTT
TGCAAGAAATGTACAAACATGAAATTGGACTGTGTTTACAGCCCTATTCAGCCAAGAAGA
AGAAAAGATTCTTCGTCGTCAAAATTTGCATCAGCGGTCCACGATAGGGTAGGCAAGAAA
AATCTGAGTGACAATGCCATCATGTTACAACAACAACAACAGCAACTTCATCATCAACAA
GAACAGCAATTTCGTCAACAACAGCAAGTTCAGTTACAGCAGCAACTGTTGCCACATGTT
GGTACTGATGAACAAAGCAATTCCCCTAATAGCGTTCCTCCATCCGTATCCAATAATATG
GAGAATCTTTTGTTACCGCACCTATTAGCGAGTTTAGTGAATAACACCAGTAACAGTACC
AACAGCAGTGCAAATGGAGCTGAAGCGCATAATAATATAACACAAACAGCTCCCAGTTCA
ATGATAAACAACAACCACCCAAACATGGCCCTACCAGGGAATTCGCCATTGAGTATACCG
ATAACACCTAGTTTTCAATCAACGGCCATGAATTTATCAAGTAGCCTTAACGGCTTACTC
TCGCCTGGTAGGCTAAATTCGGTGACGAATGGATTGCAGCAGCCACAACTTCAACAACAA
AATCAGCAAATTCCACAACAACAAGGAACACAGTCCCCCTTCAGCAATATTCCCTTCGAC
CAGCTAGCGCAATTGAACAAGATGGGCTTGAACTTCAATATGAAGAGCTTCAATACATTA
TTTCCATACGGTGCTGCAAATGGAATGGCCTCTGAGTTTCAAGAGTTATTTGGCCTCGGA
AAGTTTGCTACATCTAATAACAGAGCAATCAAAGTTAGCACAGCAGAGGAGGCACTCGCA
AATATGCAACAGGAACAGGAGGACAAAAACAAGCAATTTACGAAGAACCCATTGGATAAT
ACTAAGACGGATGCTGTTAATTCGGGCAATAACCCCCTTAACGGAAACGAAAATAAAGTT
ACTGCTTCTGATATACTATCTCATAACAAAAACTTGATAATCGACAATACCGGTCTCACA
ATCAGTCCCCCACACACGTTGTCCAAACCTTCCATAGATCAAAACATTGCGTCCCCTTCA
ACGGGAGTATCCAATGTAACCTCTACAAAGTCATTGTTATCTATACCGGACAACAGGACC
GCTTTGGGAAATTCTCCTACTTTGAAGACGTCCCCAATGGGTGACCTGTTATCCAACTCG
GAGGCATTGTCTCCACGTTCATCAAATTCTCACACTCAACAACAATCTTCTCCCCATTCA
AACGCTTCATCAGCCTCACGACTAGTCCCTGAATTAGTCGGGCTGTCTAGAAAATCAAAT
TTGAATTTGATAGATCTAAAACTTTTTCATCACTATTGTACTGACGTATGGCATACCATA
ACCGAAGCAGGCATTTCTGGTCCTGAAGTATGGAGCACTTATATTCCGGATTTGGCTTTT
CATTTTCCCTTCTTGATGCATACAATTTTGGCTTTTAGCGCCACTCATTTGTCCAGAACT
GAAGCCGGCTTGGATAACTACGTGTCTAGTCATCGTTTAGAAGCGTTGAGACTGTTAAGA
GAGGCTGTGCTCGAAATTTCAGATGATAACACAGATGCTTTGGTGGCTAGTGCTCTAATA
TTAATCCTAGATTCATTGGCAAATGCTTCAAGCAGCTCACCAACGGCATGGATTTTCCAT
GTTAAAGGCGCCGTAACTATACTAACTGCTGTATGGCCCCTGTCGGAGACATCCAAGTTT
TATAACTTAATTTCTGTTGACTTGAGTGATTTGGGTGAAGCTGTAATCAACCAAAGTAAT
CATAATAATGATAATGACAATAGCAATAATGGTGATGGAAATAACAATAATACGATATCG
GAACTCGTATGCTTTGACGAAAGTATAGCAGATTTATATCCCGTAGAAATTGATTCACCG
TACTTGATAACTTTAGCATATTTGGACAAACTGCATCGCGAAAAAAATCAATTAGATTTT
ATGTTGAGAGTCTTCTCATTTCCTGCTCTTTTGGATAGGACTTTTTTAGCATTATTAATG
ACAGGCGACCTAGGGGCCATGAGAATAATGAGGTCTTACTATACATTATTGAGAGGTTAT
ACCACAGAAATAAAGGACAAAGTGTGGTTCTTGGATAGCGTATCACAGGTTTTACCACAG
GATGTTGATGAGTATAGTGGAGGTGGTGGTATGCATATGATGCTGGATTTCTTAGGAGGT
GGGTTACCTTCTATGACCACTACAAACTTTTCAGCTTTTATGTAA
Promoter Sequence
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>ECM22 YLR228C
AACGACCTCCCAGTATTTTATATAACCTCAGCCATTTCACTGAATGATACATAGTAGCAT
ATATAGCTAGGCCTAAATGTATTTTTTTTTACAACTTTTTAGATCGCTGCGTGAAGGATG
AAACTTCATATGAGTACGGACGTTTGAAAGGGTAGAGTGGCGCTAGCATAGAAATGCCAT
TTCTCGGAGGTGTCATCATTCGAAAAGAACTCAATTTTCAAGCGATTGAGATTCAAAGGC
AAACCGATGCCTCCTCATTGGTCACATCTTCATGTAAACTGTGGCTGCTTTTTTTTCTAA
ATACTCTATGACTACAGCTTTCCTTTGTACAAACTCAAGTTTATTTAATCGTCTTTTTTA
ATGTTTATGTTCAACATACCCGAAACCACTACAAGACGGAAAATACTAGAGAAACATCAA
CAAATGAAAAAAAAAGGCTACAATCCTCGGATGAAACTGATAAAAACGAGCACAGTATAT
GCCGAGTCGTAGCATTTAACGTACTAACACTACTCGCCAAATCATAAGAGCTTCATGCTG
ACGTGTGTATCTATATCGCTTTTACAGATCCTGCAACCGACAGAGCCGAAAACGTAATTG
GTGACTCGTTCCTCGTTCTTGTCGGAAAAATTTAAACGAGCGCGTTCGATAAACTCAACG
AAGGCAAGTTTGAACAATAGATGTTGGTCGTAATCATTCGTTCTTCGACTTTTATAGCCT
TTTTTTTAACTTAACGAACTCGTACTATCTAATAGTTTATTTCCCCTTGTTTTTTTTTGT
TACGATTGGGGAAAAGCAAGGGTTCCCTGCGTCTACGATTACATCATCTACTAACTAGTC
ACCGAAATCGATTATCGTCGAAGGAGAAGCAACCAAGACCTCCACTTTTCAAAGGCACAA
ATAACATTTCGCCTTTACATAATATAGAGGAGTTAAGTCGACGGTTTTTTTCATTTAAGG
TTTATATTTCGTTTATCCATAGATCTCCATCTAACATAAC
Chr coordinates
Chr XII from 602463-600019