Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name TOP3
Systematic Name YLR234W
Alias EDR1
Strain S288c
Description DNA Topoisomerase III; conserved protein that functions in a complex with Sgs1p and Rmi1p to relax single-stranded negatively-supercoiled DNA preferentially; DNA catenation/decatenation activity is stimulated by RPA and Sgs1p-Top3p-Rmi1p; involved in telomere stability and regulation of mitotic recombination
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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>TOP3 YLR234W
ATGAAAGTGCTATGTGTCGCAGAGAAAAATTCTATAGCGAAGGCAGTTTCACAGATCCTA
GGAGGAGGCAGATCAACTTCAAGGGATTCCGGCTACATGTATGTAAAGAACTATGATTTC
ATGTTTAGTGGGTTCCCGTTTGCCAGAAATGGGGCTAACTGCGAAGTTACCATGACTAGT
GTTGCAGGGCACCTAACAGGCATTGATTTCAGCCATGATTCGCATGGGTGGGGAAAATGC
GCCATCCAAGAGTTATTTGATGCGCCACTGAACGAGATTATGAATAACAACCAAAAAAAG
ATAGCAAGCAACATCAAGCGAGAAGCGAGGAATGCAGACTATCTGATGATATGGACAGAT
TGCGACCGGGAAGGAGAGTACATCGGTTGGGAGATATGGCAGGAGGCCAAGAGAGGCAAC
AGGCTCATACAAAATGATCAAGTATACCGGGCAGTCTTTTCGCATCTCGAAAGACAACAC
ATATTAAATGCAGCACGAAACCCAAGTCGATTGGATATGAAGAGTGTGCACGCTGTAGGC
ACGCGGATTGAAATCGATCTTCGAGCAGGTGTTACATTCACCAGACTCTTAACAGAAACG
CTACGAAATAAACTGAGAAACCAAGCCACCATGACCAAGGATGGTGCAAAACACCGCGGT
GGTAACAAGAACGACTCACAAGTCGTATCGTATGGTACATGCCAGTTTCCAACGCTCGGC
TTTGTAGTAGACAGGTTTGAAAGAATACGAAATTTTGTTCCCGAAGAGTTCTGGTATATC
CAATTGGTAGTCGAAAACAAAGACAACGGCGGAACAACAACGTTCCAGTGGGACAGGGGC
CACTTGTTCGACCGGCTGAGCGTGTTAACGTTTTACGAGACATGCATCGAAACCGCCGGC
AATGTTGCTCAAGTAGTAGACTTGAAATCAAAGCCAACAACGAAATACAGACCTTTACCT
CTGACCACAGTGGAGCTACAAAAAAACTGCGCCCGGTACCTGCGTCTGAACGCCAAACAA
TCACTAGACGCAGCAGAAAAGCTATACCAAAAGGGGTTCATATCGTATCCAAGAACAGAG
ACTGATACTTTCCCACACGCAATGGACCTAAAATCCTTGGTCGAAAAGCAAGCTCAATTG
GACCAACTCGCTGCAGGCGGCAGAACCGCCTGGGCATCGTACGCGGCATCGCTGCTCCAA
CCCGAAAACACAAGTAACAATAACAAGTTCAAGTTTCCACGAAGCGGCTCCCATGACGAC
AAAGCGCATCCACCAATCCACCCCATCGTAAGTCTGGGGCCTGAAGCAAATGTTTCGCCA
GTGGAAAGAAGAGTATACGAGTACGTGGCCAGGCACTTTTTGGCATGCTGCTCAGAGGAC
GCCAAGGGCCAATCGATGACCCTTGTGTTGGACTGGGCCGTTGAACGTTTCTCAGCTTCA
GGTCTCGTAGTCCTAGAGAGAAATTTCCTCGATGTTTACCCTTGGGCCCGATGGGAAACC
ACCAAGCAGTTACCGCGGCTTGAAATGAATGCCCTCGTAGACATCGCGAAGGCCGAAATG
AAGGCGGGCACTACGGCGCCGCCCAAGCCGATGACTGAGAGTGAACTCATTCTCCTCATG
GATACAAACGGCATTGGCACAGACGCCACCATTGCGGAGCACATAGACAAGATCCAAGTA
CGTAATTACGTTAGGAGCGAGAAAGTAGGCAAGGAAACCTACTTACAACCCACGACCCTG
GGTGTCTCACTAGTGCACGGCTTCGAGGCCATCGGCCTCGAAGACTCCTTTGCAAAGCCC
TTCCAGCGCAGAGAAATGGAGCAAGACCTCAAGAAAATCTGCGAAGGTCATGCCTCCAAG
ACTGATGTTGTAAAGGACATAGTCGAGAAGTATAGGAAGTACTGGCACAAGACGAATGCC
TGCAAGAATACTCTCTTGCAAGTTTATGACCGTGTCAAGGCATCCATGTAA
Promoter Sequence
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>TOP3 YLR234W
TTTTCGCTCGTTGAAAATAAGTATCTCCAACGGCTGGGAGATAGAGTGAGGCAATATTCA
AGTACCTAATAGACTTCTCAAAACCTTCCACACTCTTGGGTTTGTTAGACGGCTTGTTTA
GTAGTGTTTTATAAAAATGTGTGGAACCTAGATTAATCACGCATCTTTGTAGTGAGATTA
CAATGGAAAACGTCAGTGGATTACTCGTGTTTAAGATAATTTTCTCATGAGTTGAAAGTC
CATCTGTGTATTGCATTAAATTCAACTTCGCGAAGAGAGCATTTGAAATAACGGAATTCA
TATCGTACTTTGCGCATAGGTGTTCGATGATGTCATAGTAATACCTGTGTGTAATTTTGA
AAAATTGAATCATTTTTTTTTGAAAAATTCTAAAAACTCTGAACTTTCTTCTGTTACTTA
GTCGCATGATATCATGGAACCAGTGCTCAAACCATTGGAGTGTAGGTTCGTGAATTTGAA
GCCATAAAAGTTTCAGAACCAATGGTATCACGGAATCATTTATGCGTTCGTAATTGTTAT
TATGGTACATATTTTCTTGTTTCAAAAGTAGCTCTTCGAGAAACCTAGTAGATTTGCGAT
GTATTCCATCCAGGAAGCATCTGAACGTGATATATGCATTTTCATCGCATGTCAACCTTG
ATGTTAGATGTTTATCCAGATGCGCACGAGCGTTCTTGAAAAATAATCTCATACATTCTT
CGTTAACTTCTTCATTATCCATTATCTATGGTGGCATGTGTCATTTAATGGAATATACTT
TTTCCCCTGATAAGTTTGCTAAAAACGGTCGGATCATACAGGCATGTTAACATTTCCATT
ATCCTTTTTGACATTGGATAATGGCGTGAACGCGAAAATCACATTGATAAAAAAAAGCAG
TTTGGCGAATTAGTAACTGTCAATAAAGAGGGCATCGCTTTTGAAAGCACCTTCGTCTGT
GCGCTCGCTTCAGCTACGTAAAGGTGTATTATAGACAATA
Chr coordinates Chr XII from 609783-611753
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