Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
TOP3
Systematic Name
YLR234W
Alias
EDR1
Strain
S288c
Description
DNA Topoisomerase III; conserved protein that functions in a complex with Sgs1p and Rmi1p to relax single-stranded negatively-supercoiled DNA preferentially; DNA catenation/decatenation activity is stimulated by RPA and Sgs1p-Top3p-Rmi1p; involved in telomere stability and regulation of mitotic recombination
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>TOP3 YLR234W
ATGAAAGTGCTATGTGTCGCAGAGAAAAATTCTATAGCGAAGGCAGTTTCACAGATCCTA
GGAGGAGGCAGATCAACTTCAAGGGATTCCGGCTACATGTATGTAAAGAACTATGATTTC
ATGTTTAGTGGGTTCCCGTTTGCCAGAAATGGGGCTAACTGCGAAGTTACCATGACTAGT
GTTGCAGGGCACCTAACAGGCATTGATTTCAGCCATGATTCGCATGGGTGGGGAAAATGC
GCCATCCAAGAGTTATTTGATGCGCCACTGAACGAGATTATGAATAACAACCAAAAAAAG
ATAGCAAGCAACATCAAGCGAGAAGCGAGGAATGCAGACTATCTGATGATATGGACAGAT
TGCGACCGGGAAGGAGAGTACATCGGTTGGGAGATATGGCAGGAGGCCAAGAGAGGCAAC
AGGCTCATACAAAATGATCAAGTATACCGGGCAGTCTTTTCGCATCTCGAAAGACAACAC
ATATTAAATGCAGCACGAAACCCAAGTCGATTGGATATGAAGAGTGTGCACGCTGTAGGC
ACGCGGATTGAAATCGATCTTCGAGCAGGTGTTACATTCACCAGACTCTTAACAGAAACG
CTACGAAATAAACTGAGAAACCAAGCCACCATGACCAAGGATGGTGCAAAACACCGCGGT
GGTAACAAGAACGACTCACAAGTCGTATCGTATGGTACATGCCAGTTTCCAACGCTCGGC
TTTGTAGTAGACAGGTTTGAAAGAATACGAAATTTTGTTCCCGAAGAGTTCTGGTATATC
CAATTGGTAGTCGAAAACAAAGACAACGGCGGAACAACAACGTTCCAGTGGGACAGGGGC
CACTTGTTCGACCGGCTGAGCGTGTTAACGTTTTACGAGACATGCATCGAAACCGCCGGC
AATGTTGCTCAAGTAGTAGACTTGAAATCAAAGCCAACAACGAAATACAGACCTTTACCT
CTGACCACAGTGGAGCTACAAAAAAACTGCGCCCGGTACCTGCGTCTGAACGCCAAACAA
TCACTAGACGCAGCAGAAAAGCTATACCAAAAGGGGTTCATATCGTATCCAAGAACAGAG
ACTGATACTTTCCCACACGCAATGGACCTAAAATCCTTGGTCGAAAAGCAAGCTCAATTG
GACCAACTCGCTGCAGGCGGCAGAACCGCCTGGGCATCGTACGCGGCATCGCTGCTCCAA
CCCGAAAACACAAGTAACAATAACAAGTTCAAGTTTCCACGAAGCGGCTCCCATGACGAC
AAAGCGCATCCACCAATCCACCCCATCGTAAGTCTGGGGCCTGAAGCAAATGTTTCGCCA
GTGGAAAGAAGAGTATACGAGTACGTGGCCAGGCACTTTTTGGCATGCTGCTCAGAGGAC
GCCAAGGGCCAATCGATGACCCTTGTGTTGGACTGGGCCGTTGAACGTTTCTCAGCTTCA
GGTCTCGTAGTCCTAGAGAGAAATTTCCTCGATGTTTACCCTTGGGCCCGATGGGAAACC
ACCAAGCAGTTACCGCGGCTTGAAATGAATGCCCTCGTAGACATCGCGAAGGCCGAAATG
AAGGCGGGCACTACGGCGCCGCCCAAGCCGATGACTGAGAGTGAACTCATTCTCCTCATG
GATACAAACGGCATTGGCACAGACGCCACCATTGCGGAGCACATAGACAAGATCCAAGTA
CGTAATTACGTTAGGAGCGAGAAAGTAGGCAAGGAAACCTACTTACAACCCACGACCCTG
GGTGTCTCACTAGTGCACGGCTTCGAGGCCATCGGCCTCGAAGACTCCTTTGCAAAGCCC
TTCCAGCGCAGAGAAATGGAGCAAGACCTCAAGAAAATCTGCGAAGGTCATGCCTCCAAG
ACTGATGTTGTAAAGGACATAGTCGAGAAGTATAGGAAGTACTGGCACAAGACGAATGCC
TGCAAGAATACTCTCTTGCAAGTTTATGACCGTGTCAAGGCATCCATGTAA
Promoter Sequence
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>TOP3 YLR234W
TTTTCGCTCGTTGAAAATAAGTATCTCCAACGGCTGGGAGATAGAGTGAGGCAATATTCA
AGTACCTAATAGACTTCTCAAAACCTTCCACACTCTTGGGTTTGTTAGACGGCTTGTTTA
GTAGTGTTTTATAAAAATGTGTGGAACCTAGATTAATCACGCATCTTTGTAGTGAGATTA
CAATGGAAAACGTCAGTGGATTACTCGTGTTTAAGATAATTTTCTCATGAGTTGAAAGTC
CATCTGTGTATTGCATTAAATTCAACTTCGCGAAGAGAGCATTTGAAATAACGGAATTCA
TATCGTACTTTGCGCATAGGTGTTCGATGATGTCATAGTAATACCTGTGTGTAATTTTGA
AAAATTGAATCATTTTTTTTTGAAAAATTCTAAAAACTCTGAACTTTCTTCTGTTACTTA
GTCGCATGATATCATGGAACCAGTGCTCAAACCATTGGAGTGTAGGTTCGTGAATTTGAA
GCCATAAAAGTTTCAGAACCAATGGTATCACGGAATCATTTATGCGTTCGTAATTGTTAT
TATGGTACATATTTTCTTGTTTCAAAAGTAGCTCTTCGAGAAACCTAGTAGATTTGCGAT
GTATTCCATCCAGGAAGCATCTGAACGTGATATATGCATTTTCATCGCATGTCAACCTTG
ATGTTAGATGTTTATCCAGATGCGCACGAGCGTTCTTGAAAAATAATCTCATACATTCTT
CGTTAACTTCTTCATTATCCATTATCTATGGTGGCATGTGTCATTTAATGGAATATACTT
TTTCCCCTGATAAGTTTGCTAAAAACGGTCGGATCATACAGGCATGTTAACATTTCCATT
ATCCTTTTTGACATTGGATAATGGCGTGAACGCGAAAATCACATTGATAAAAAAAAGCAG
TTTGGCGAATTAGTAACTGTCAATAAAGAGGGCATCGCTTTTGAAAGCACCTTCGTCTGT
GCGCTCGCTTCAGCTACGTAAAGGTGTATTATAGACAATA
Chr coordinates
Chr XII from 609783-611753