Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
THI7
Systematic Name
YLR237W
Alias
THI10
Strain
S288c
Description
Plasma membrane transporter responsible for the uptake of thiamine; contributes to uptake of 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (acadesine); member of the major facilitator superfamily of transporters; mutation of human ortholog causes thiamine-responsive megaloblastic anemia
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>THI7 YLR237W
ATGAGTTTCGGTAGTAAAGTCTCCAGGGCTTTGAGATTTTTGGAAATTCCTGTCAAAGAC
AGGGCATCTGTGAGTTTCTTGAAGAACCCGGATTTGCAACCTATTAAGTCGGCTAACCAA
ACATGGGGGTTCTGGTCTAATTTTGCATATTGGGGTGTTATGTCCTTTTCAGTGGGTACA
TGGATGAGTGCCTCTTCTGCACTAGGTGTTGGATTAAGTTACCCAGAAACCATTGGTACA
TTTATCGTCGGTGATGTGTTGACCATTATTTTCACATTGGCAAACTCGTGTCCTGGTTAC
GACTGGAAGGTCGGTTTCACTTTGGCCCAAAGATTCGTCTTTGGTATTTACGGTTCTGCC
TTCGGTATCATCATCAGAATTTTGATGAGTATTGTCAACTACGGGTCCAACGCTTGGGTG
GGAGGTCTTTGTATCAATATGATCTTGGATTCATGGTCTCACCATTATTTGCACCTGCCA
AACACCTTATCTTCGAAAGTTGCCATGACCACTAAAGAATTAATTGGTTTTATCATCTTC
CACGTCCTTACTGCATTCTGTTACTTAATGAAACCCTACCACATGAACTACATTTTAATT
TGGTCGTGTGTTGCTACATTTTTCTCTATGTTGGGTATGGTGATCTATTTAGCTAAACAG
GCTCACGGTGTTGGAGAATTGTTTACCTCCACTAAATCCACTGCCACTGGCTCCACCAAA
GCTTGGGCTTGGGTTTATATGATCTCGTACTGGTTCGGTTCCGTTTCTCCAGGTTCCACC
AACCAAAGTGATTACTCGAGATTTGGTTCCTCCAATTGGGCTATCTGGGCCGGTACCATC
TGTGCATTGTTAATTCCAACCACTTTAATCCCAGTTTTTGGTGTTATTGGTGCCTCCACC
TGTGACAAACTATACGGTGAACAATATTGGATGCCTATGGATATCTTCAACCATTGGTTG
ACAACTAACTATTCTGCAGGTGCTCGTGCCGGTGCGTTCTTCTGTGGTCTTTCATTTGTC
CTATCTCAAATGTCCTACACCATCTCCAACTGTGGGTTTGCCAGTGGTATGGATTTGGCC
GGTTTATTACCCAAGTATGTCGACATCAAGAGGGGTGCCCTTTTTGCCGCATGTGTCTCC
TGGGCTTGTTTGCCATGGAACTTCTACAACTCTTCTTCTACTTTCTTGACTGTCATGAGT
TCTTTCGGTGTTGTCATGACTCCTATCATTTCTGTCATGATTTGCGATAACTTCTTGATC
AGAAAAAGACAATACTCCATCACTAATGCCTTTATTCTCAAGGGTGAATACTATTTCACT
AAGGGTGTTAACTGGAGAGCTATTGTTGCCTGGGTTTGTGGTATGACCCCCGGTCTACCT
GGTATTGCTTGGGAAGTCAATAATGACTATTTCCACAACACTGGTATTGTCAATTTCTTT
TACGGTGACTCCTTCTTCTCGTTTTTGATCTCCTTTTTCGTCTATTGGGGACTATGCCTC
CTCTTCCCATTCAAAATTACTGTCAAACATGATGACAAAGATTATTATGGTGCCTTTACT
GACGAAGAAGCAAGAAAGAAGGGCATGGTTCCATACAGTGAAATTTCTGAAGAAGAAATC
CGCGCTTACACATTAGGCGAAGGTTACACTACCGGCCACGAGTACAGACCTGAAGGCTCC
GACGATGAAATACCTGAGTTGGTCAAAACTAGCTCTGAAAACACCAATGAGTTTGAAATA
GTTCATCATAAGAATAATGAAAAGCAATCCTCCACCGCCAGTGAAAAAGCTGCTTAG
Promoter Sequence
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>THI7 YLR237W
AAGCCGATGACTGAGAGTGAACTCATTCTCCTCATGGATACAAACGGCATTGGCACAGAC
GCCACCATTGCGGAGCACATAGACAAGATCCAAGTACGTAATTACGTTAGGAGCGAGAAA
GTAGGCAAGGAAACCTACTTACAACCCACGACCCTGGGTGTCTCACTAGTGCACGGCTTC
GAGGCCATCGGCCTCGAAGACTCCTTTGCAAAGCCCTTCCAGCGCAGAGAAATGGAGCAA
GACCTCAAGAAAATCTGCGAAGGTCATGCCTCCAAGACTGATGTTGTAAAGGACATAGTC
GAGAAGTATAGGAAGTACTGGCACAAGACGAATGCCTGCAAGAATACTCTCTTGCAAGTT
TATGACCGTGTCAAGGCATCCATGTAAGGCGTTTTTGCCGCCCTTTGTCTTCAAAAAAGC
TCTCCGCTTAATTGCATGATTCAGCTGACTGCATATGTGCATTTTCAGTACCAGCCGCAA
CTGCATCAAACCATGCAGAAGTCGCCGCCACAGAAGCTCCAGCGCGCCGCGTAAACGCAT
GTTGGAAGGCGCCCCAATTAGCATATTCACGCGCGACTACCAAACGCATAGGGAAGGTTT
CAGAGAGCCGATGAGCAGCGGATGCACAGAGTACGGCCATAAGGCTGCAAAGCGCTTGGC
AGGAATGGGCGTTTTCTAGAGGTTGCCTTATTGATTTATATGGAAGAGGAGAGGATTCAT
CGATCGGGCTTCTAAGGCAAATAGTATGCATACCTTTTTCGGGTAGTTGAAGAGAAAAGA
GGAAGAGAATAGAAAAAAAAAAAAAGCGAAATTTTTACATCCTCTATTGTAATGTAATTT
CTTTTTTTTTATTAGGTATATATGTGAGATACAATTCTCGAAGTCATCGGGAAGCTTTAC
CATTTCATTTCCTATTCCAGAACTCATATTAGCATCTATTGTTCTGAGATTCATCGCAAC
ATCATTTAAAGGACTGTAGAGCCAATTGCATTATATCAAT
Chr coordinates
Chr XII from 612367-614163