Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name IRC20
Systematic Name YLR247C
Strain S288c
Description E3 ubiquitin ligase and putative helicase; involved in synthesis-dependent strand annealing-mediated homologous recombination; ensures precise end-joining along with Srs2p in the Yku70p/Yku80p/Lig4p-dependent NHEJ pathway; controls 2-um plasmid copy number by regulating the levels of the Flp1p recombinase; localizes to both the mitochondrion and the nucleus; contains a Snf2/Swi2 family ATPase/helicase and a RING finger domain; null mutant displays increased levels of spontaneous Rad52p foci
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>IRC20 YLR247C
TACCGCTTGACCTGGTCTTACCCTTGAATGGTTTTTTAGATTCCTGAGACAAATCTGCCT
GATCCGGTTTCTTTTTCGAGAAAAGGGCCTTTATTTTAAGCATCGAAGAGATTTTGTTTG
ATCCTCTCTAAATAAGCAGTACTCTTAACAATACTTTCGTCTTTTCCAATCGTTAAATGT
TTGTACTTCAAATAACGTATGAACTATCTGGGATTTTATTTTCTTTAATTTTTTCGATGT
CACTCTTTTTTTTTCTTTGGCCGATCCGTCTTTTCTAGTAAGCGTTTGTAAAAAGTTAGA
TGTCAATAGGAGAGATAAAGCCCCAGAGATAGAGTTTGACTTCGTTGAAATAACTGTCGC
TGATTACTATTATCTAGGATTCTTGACGAGGTTTCCTCTTAATCACTGGATTTATAATTA
TAACCTTAAACCTAGCCAGTAAAAAAGTTTAAAAAGAACAAAAAACAATAACAAATAAAT
GTCCCTTTATCCTCCTTTTTTCTCTTGATTGCTATAAAGTAAAAAGATTACTAGACTTTA
TGCCAACGTACTCGTGGACGACTAAAACTAACGGTGATTTTTTGGATCGTAGTGGCTCTT
TTTCAGCCTTCGTACTTTCAAGAATAAAGGAAATGGCAACTACTAAAAAGAGTGCCTGCG
CAACGGATGTTTTATTAGCTTGAAGATGTAGCTGAATAACTCCTGTTTTTAAGTGAGCTC
GAAATGACGAACCAGTCAAAGAACAAACTTGACCGCAAATACAGGGACATCCAAGGAGTC
TGGGATAGCTTCACTCCTATGAGAGCTCAAGGAATTACCTGCTCGCATCTCTGACCAAGG
ATAAGGCTCGTTTTTTCCTTTTTCGGAACACTCGAACTGCTACCCGTCTTTTCCAGATCT
ACAGCTGATGAAATGTGGCTGATGAATGTATTGATTTGCCACTTTCTAGGCGCTGTCTAA
AGGAATGAACTCCAGGAAAGGCCAACTTATTCGACGGTAA
Chr coordinates Chr XII from 633354-628684
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