Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
IRC20
Systematic Name
YLR247C
Strain
S288c
Description
E3 ubiquitin ligase and putative helicase; involved in synthesis-dependent strand annealing-mediated homologous recombination; ensures precise end-joining along with Srs2p in the Yku70p/Yku80p/Lig4p-dependent NHEJ pathway; controls 2-um plasmid copy number by regulating the levels of the Flp1p recombinase; localizes to both the mitochondrion and the nucleus; contains a Snf2/Swi2 family ATPase/helicase and a RING finger domain; null mutant displays increased levels of spontaneous Rad52p foci
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>IRC20 YLR247C
ATGTCTGCAGTAGGTGCGCTATTAGCAAGGGAGTACAACGTGACTGCCGAAAAATGCGAC
TTTTTCCTAGAAAATGGTTCTTTTGATTCAGTGATAGCAGCATTGCCAGCGCTAAATCAG
GAACAAGAGACTGTAACTCAAAAAGTTAGCAAGAACGGAAAAGAATTAATCAACGTTGCC
TCGGTAAATATCGAAATACCAGAGCGAATAAGTCTTTCCAACAACGGTAGGCAGTTATTT
AAATTTATTGTTGATATAGAGATCTTACCTTGTGAAAATGATAACGAGGCAACACTTGTT
GTGTCGTCAGATTCCGTATCCTTATTTCAAATTGGATTTAAAATGGAGAACAATTCAAAA
ATCGCTGTTGACAAACAACTTCCGCTGATCTTGGATATATGTGCTCATAAAAACCAAGAA
AGGGCCCTACGAAATCAGTTAGAAAATCGTAAATCTTTAGAACGCAAACCATCAAGAAAG
AGAAGAAAAAAAAATTCAAATGTTAACGATCCTGAAAAATTACTAAAAAGTCGTATACAC
GAATTATCTTTGTCCTACAAAGATTTTGAATGCTCTCCAGTCGTATTCCGATACAATGAT
TCCTCTTTAACATGGGTTTTATCTTTTAATTTGAAGTTGAAGTTTTTAAATAATAAATTC
AACCGGTTTTCCGTGGAGGCTAACCAAATACTGGACTTGACGTTCTCTAATAGGGACGAG
AACGAATTTGAGCGATATCACAAGCACAGCCATATCCATTCAAACTTCATTCAAAAACAA
TTTATTTCTCAAATCTTGGAATATAGTAAAGATAGGCTATCAAAGATCAAACCGTTCTTA
CCCCAATCTATACCAGACCTAAAAGTTAACCTCTTACCATTTCAAAGAGAGAGCGTTGAG
TGGATGCTAATTAAAGAAGGGCATGGTAATTCTCTTAGTGATACACCTACAGTCATCGAC
GAAGTAGGGCTTATAGATTTTATGAACGAGTACTATGCATACGGTTACGAGCTCATTGCA
CGCAGCCCTGACGAGGTAGGGCCATCATTGTTATGGAACAAATTAACAGGATATATTCTA
ACTACAGAAGATGCTGCACATTTGTACAACCAATATAGGAAGGAAAGGTTAAGCGGCGAC
TACCCAGTTTGTGCAAAGGGGGTGTTAGCAGAAGAGATGGGGTTGGGCAAAACTATTGAA
ATTTTATCACTAATACTCTTAAATAGAAGGAAATTGAAGGACTCAGAGGCAACATTTATT
GACGATGAAAATAGAACAATCACGAAGACAAAGACGACTTTGATTATCTGTCCCAATGCT
ATCTTAAAACAATGGCTCGAAGAAATCGAATTACACGCAAATTCCTTAAAATGGTATACC
TATAGAGGATATAATGAGATAATGAAAGATTGCAAAACTGTGGACGAAGCTGTTCAACAA
TTGTGCCAATACGATATTATAGTTACATCATATAACATTATTGCCACGGAGGTCCATCAT
GCTGAGTTTAACCGTAGTATCAGATCGAGAAGGTTGAAAAGCCCAAAGTATGACTATTCT
TCACCGTTAGCTTTGATGCAGTTTTATAGAATCATTCTGGATGAAGTTCAAATGCTACGT
AGTTCATCAACATATTCTGCAAAATGCACGAGTTTACTTCATAGAATACACACTTGGGGT
GTTTCCGGGACTCCAATACAGAACATTTACAACTTTAGGATGATCATGTCTTATTTAAAG
CTGCATCCATTTTGTGATGAGGTAGACTTTATTCGGACACTTCAAGAAGAAATTAAACTA
AGAAATGAGGCTAAAGATTACACTAGTAATGATTTTGTATGCCAATTAAAGGGCGTTCGG
TTTTCTATCAAGGATTGTATGAACATTTTTTACAGGTATGATCTTTGCATAAGGCATTCG
AAAGCCAATGTTGCGTCTCAGATTCATATTCCGCGGCAACACAACTTCATCATTCCCCTG
GAGTTTGCGCCTATCGAGTGGGACAACTATTTAAATCTTTGGAACAATTTTTTAGAGTTG
AGTGGCTATAATTCGGATGGCAGTGGATCACCCCGTGTAAGCAATGCCTTTTTAAACGAA
TGGTTGTCTAGGCTGCGATATATATGTTGCCATGCATTATTTCCAGAAATTTTAAGTACC
CGACAGAAGCGCCTTCACGGGCACTTGTCAAGAATTTCAAATATAGACGATATCTTAATA
TCCATGCGAATGGATGCATTTGACAGTTTAATTGGCTATTACAGAGAGAGATTCCATTTA
TCGATCAAGCAGGCACAGTATGAACTTGAAATTTCCAATACTCCGGCCAAAGCCCTTGAA
TCATTTATCAAAATCAGAGATGATTTGATGATACACATACGCCAAAAATTCAACGTTGAG
GATCCGTTTGATAAGTCGTTAAACCTCAGTGAAGATGAGGACGAACATATGGACGAGAGG
TTTGGTGAGAAGGAAACATCTTCAGGCGACGAAAGCGATAGAGAAATAAATGGTGCTAAA
AACCATGATAATCACAACAATGACGGAATGTTATCCAACCACCTGAAGAAGAAAGGATTA
CGTGCTATGATGAATTTACTGCATGATTGCTACTTCTTCCTCGGTTCTGTTTACTATAAC
TTGGGCACTCGTAAGCTAGAAGAGGCGGACGACAAGCATCGAAAAGAGAAGACTGAAGAA
GTGGTGTATTCTGATGTTTTTCCAAAAAATGAGTTAGAGGAAATTGAAGAGAATAGACTT
TTAGAACAAGAAAATTATGCGAATGCAGAAATTTTGAGGAAGTCAATCCTCTCCTCTGAG
GCTAGAAAAGTTGATATGACTATTAAAATGGCCAGAACTAAGTTTGCTCCTATGACGAGC
AATATACCTTTGCGATTAATCAATATTGAATTTGACCACAAAAATGACTACTCATCTAAT
TTAGCAGTATCTCGTTGTTTCAAGTCTTTGAGTAAGTTGATAGAAGGGTTGAATGAACAA
ACTAAAAACTTCAACGAGTTATTGGATGAGTTACTCATTATTATCTATGAACCTGTCCAC
AGGACAGAGGACGATGATAGCACTAATAAAATTATCGGTAATGAAGAATATTCAACATCG
ATTGACAGTCAAGATAAGATATTCAGTCTTCTTGGTTGCTTGGAGATAATTTTACAGAAT
AGGGACAATATTTTAACTTCAGAATCAGAAGTTAAAATTCCGAAGCATTTGGTACCGGAA
GGTTCAATAATTTCAAAATATCAAAAGCAGTTATTGAACAGCTTGCGCTTGATTTCAGGA
ACACCTCTACGAACTGTTTTTGATGAACTGAAGAACAGCAGGATAGTAAGACGGATATCC
TCAAGCAATGAAAGTGAATCTACCATTCAAAATTTTGAGGACTACTTACTTCAGTACGAA
GTTGAAAGTAAAAGCCTGTTTAAGTACAATAAACAGGTAAGAGAATCTTTGAAAATCCTG
GGATCGATTTATAATGCCAAGACGGAATATTATAGTCAATTACAGAGGATTTCCGATTCA
TTGGTGTCCTTGCACTCTTTGAGTGCTCCACAACTCAGCCATCTAATAAGAACTATCAAT
AAGTCATTGGGCGGTACACTAGATGCAAAAATCAATAACATTGAATCACGGCTGATATAT
TTAAAAAATTTGTCCAGATTGAAAGACACATTAAACGATAATCAAATATTGAGCTGCTCT
ATCTGTTTGGGAGAAGTTGAAATAGGTGCTATCATTAAGTGTGGACATTATTTTTGCAAG
AGTTGTATCCTTACGTGGCTACGAGCCCATAGTAAATGCCCTATATGCAAAGGTTTCTGT
AGTATATCGGAAGTCTATAACTTTAAGTTCAAGAACTCAACGGAGAAGAGGGAAAAAGAA
ATTCAAGAGCCACGAAGAGAGGGCGCCGATTCGTCTCAAGATAATTCAAATGAAAACTCG
ATTATATCCAATATGAGTGAAGTAGAAAAATTATTCGGAAATAAATACGAGCAATTCCAT
CAAATTAATGAAGTCCATCAAATTCACATAAAGGAAAGTTTTGGTGCTAAGATTGATTTC
GTCATCAAGTTAATATCTTACCTGAGGCTAAAAAGTGAGCAGGAAAACGCTGATCCGCCA
CAAGTTATTCTATACTCTCAAAAGACAGAATATTTAAAGGTCATTGGTAAGGTATTAAAG
TTGTATCACATTGAACACTTGGCATGTCTATCTAATACAGCCAATGTTGGCGAAACTATA
AATAACTTCAAACGCCAGCCTTCCGTCACTTGCCTACTTTTGAATGTGAAAACTTTAGGT
GCCGGCCTGAATTTGATAAATGCAAAACATATTTTCCTACTAGATCCTATCCTTAATAAT
AGTGATGAATTACAAGCTATGGGAAGGAATAATCGTATAGGACAAGATGAAGAAACTTTT
GTGTGGAATTTCATGATCAGAAATACCGTTGAAGAAAACATCCTCAGATATAAATGTATA
CTCGAAGAGCGCAAAAGAAAGGAGAAGTCAAAAAAAGGCGATAAATACGACGAAGCACAA
GATGAAACGGATAATGAGGAAAGCGATGATGCGAAGTTTGAGATAAGCGTGGTAGACCAA
GAAGTCAGTAATGAACACTTATGGAACTGCTTTTTTCACGGTAGTGATTAG
Promoter Sequence
Download FASTA
>IRC20 YLR247C
TACCGCTTGACCTGGTCTTACCCTTGAATGGTTTTTTAGATTCCTGAGACAAATCTGCCT
GATCCGGTTTCTTTTTCGAGAAAAGGGCCTTTATTTTAAGCATCGAAGAGATTTTGTTTG
ATCCTCTCTAAATAAGCAGTACTCTTAACAATACTTTCGTCTTTTCCAATCGTTAAATGT
TTGTACTTCAAATAACGTATGAACTATCTGGGATTTTATTTTCTTTAATTTTTTCGATGT
CACTCTTTTTTTTTCTTTGGCCGATCCGTCTTTTCTAGTAAGCGTTTGTAAAAAGTTAGA
TGTCAATAGGAGAGATAAAGCCCCAGAGATAGAGTTTGACTTCGTTGAAATAACTGTCGC
TGATTACTATTATCTAGGATTCTTGACGAGGTTTCCTCTTAATCACTGGATTTATAATTA
TAACCTTAAACCTAGCCAGTAAAAAAGTTTAAAAAGAACAAAAAACAATAACAAATAAAT
GTCCCTTTATCCTCCTTTTTTCTCTTGATTGCTATAAAGTAAAAAGATTACTAGACTTTA
TGCCAACGTACTCGTGGACGACTAAAACTAACGGTGATTTTTTGGATCGTAGTGGCTCTT
TTTCAGCCTTCGTACTTTCAAGAATAAAGGAAATGGCAACTACTAAAAAGAGTGCCTGCG
CAACGGATGTTTTATTAGCTTGAAGATGTAGCTGAATAACTCCTGTTTTTAAGTGAGCTC
GAAATGACGAACCAGTCAAAGAACAAACTTGACCGCAAATACAGGGACATCCAAGGAGTC
TGGGATAGCTTCACTCCTATGAGAGCTCAAGGAATTACCTGCTCGCATCTCTGACCAAGG
ATAAGGCTCGTTTTTTCCTTTTTCGGAACACTCGAACTGCTACCCGTCTTTTCCAGATCT
ACAGCTGATGAAATGTGGCTGATGAATGTATTGATTTGCCACTTTCTAGGCGCTGTCTAA
AGGAATGAACTCCAGGAAAGGCCAACTTATTCGACGGTAA
Chr coordinates
Chr XII from 633354-628684