Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
YSH1
Systematic Name
YLR277C
Alias
BRR5
Strain
S288c
Description
Endoribonuclease; subunit of the mRNA cleavage and polyadenylation specificity complex; required for 3' processing, splicing, and transcriptional termination of mRNAs and snoRNAs; protein abundance increases in response to DNA replication stress; YSH1 has a paralog, SYC1, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>YSH1 YLR277C
ATGGAGCGAACAAATACAACAACATTCAAATTTTTTTCATTGGGAGGAAGTAACGAAGTT
GGACGATCATGTCATATATTGCAATATAAAGGTAAAACAGTGATGCTCGACGCAGGAATT
CATCCGGCATATCAAGGATTAGCTTCATTACCTTTTTACGATGAATTTGATCTTTCCAAA
GTCGATATCTTACTGATATCACATTTCCATTTAGACCATGCCGCTTCACTTCCGTATGTG
ATGCAACGGACTAACTTTCAAGGCAGAGTTTTCATGACACATCCAACCAAAGCCATTTAC
AGATGGCTACTGCGAGATTTTGTAAGAGTTACTAGTATAGGTTCTTCATCCTCCTCTATG
GGGACTAAAGACGAAGGTCTATTCTCAGATGAGGATTTAGTTGATTCTTTCGATAAAATT
GAAACGGTGGACTATCATTCTACTGTTGACGTCAATGGTATCAAATTTACGGCATTCCAT
GCAGGCCATGTATTGGGTGCAGCGATGTTTCAAATAGAGATTGCTGGCCTTAGGGTGTTA
TTCACAGGTGACTATTCGAGAGAAGTAGATCGTCACTTAAATTCTGCTGAGGTGCCTCCA
CTTTCATCCAACGTATTAATTGTGGAATCTACCTTTGGTACCGCTACTCACGAGCCCCGT
TTAAATAGAGAAAGGAAGCTAACCCAACTAATCCATTCCACAGTGATGAGAGGAGGCCGT
GTTCTACTGCCTGTTTTTGCTTTAGGGAGAGCTCAAGAAATCATGCTTATACTGGATGAG
TACTGGTCTCAACATGCTGATGAACTCGGTGGTGGACAAGTCCCAATATTTTATGCATCA
AATTTGGCAAAAAAATGTATGAGCGTTTTTCAAACCTATGTAAATATGATGAATGATGAC
ATTAGAAAAAAATTTAGAGACTCTCAGACTAATCCCTTCATATTCAAAAATATATCTTAT
CTTAGAAACTTGGAGGATTTCCAAGATTTTGGTCCCAGTGTGATGTTGGCCTCACCAGGT
ATGCTGCAAAGTGGGTTATCAAGAGATTTACTTGAAAGGTGGTGCCCTGAAGATAAAAAT
CTAGTACTAATCACCGGTTACTCCATCGAAGGAACAATGGCGAAATTTATTATGCTTGAG
CCAGATACAATACCTTCCATAAATAATCCGGAAATAACCATTCCAAGACGTTGTCAAGTT
GAAGAAATCTCCTTTGCCGCACACGTTGACTTCCAGGAAAATTTAGAATTTATTGAAAAG
ATTAGTGCGCCAAATATCATCCTTGTTCATGGAGAAGCCAATCCCATGGGCCGTTTGAAA
TCTGCATTGTTATCCAATTTCGCGTCTTTAAAGGGTACAGATAATGAAGTCCATGTTTTT
AATCCTAGAAACTGTGTTGAAGTAGATCTTGAATTTCAAGGTGTCAAGGTTGCAAAAGCT
GTGGGAAATATTGTGAACGAAATATATAAAGAAGAAAACGTAGAGATAAAGGAAGAAATT
GCGGCTAAAATTGAACCTATAAAGGAAGAAAACGAAGACAACTTGGATTCTCAAGCAGAA
AAAGGTTTGGTTGATGAAGAGGAACACAAAGACATAGTCGTTTCTGGGATTCTAGTTTCA
GATGACAAAAATTTCGAATTAGACTTCCTTTCTTTGTCTGATTTAAGAGAGCACCATCCC
GATCTTTCTACAACGATATTAAGAGAGCGCCAGTCAGTTCGTGTAAATTGTAAAAAGGAG
CTAATTTACTGGCACATTTTACAAATGTTTGGAGAGGCTGAAGTTCTTCAAGATGATGAT
AGAGTAACAAATCAAGAACCAAAGGTTAAAGAAGAGTCAAAAGACAATCTGACCAATACA
GGTAAATTGATTCTACAGATAATGGGTGATATTAAGTTAACTATTGTTAATACTCTAGCC
GTTGTGGAATGGACTCAAGATTTAATGAATGACACTGTAGCAGACTCCATTATTGCTATA
CTTATGAATGTGGATTCAGCTCCCGCCAGTGTCAAGCTTTCGAGTCATTCTTGTGATGAT
CATGATCATAACAATGTGCAGTCTAATGCACAAGGTAAGATTGATGAAGTTGAGAGGGTG
AAGCAAATCTCAAGGTTGTTTAAAGAACAGTTTGGTGACTGTTTTACTTTATTTCTCAAT
AAAGATGAATATGCAAGTAATAAAGAGGAAACTATAACTGGAGTGGTTACCATAGGTAAA
AGCACTGCTAAGATTGACTTCAACAATATGAAAATTTTAGAATGTAATTCAAATCCTTTG
AAAGGTAGGGTGGAAAGCCTCTTAAATATTGGTGGTAATTTGGTCACACCGCTATGTTAA
Promoter Sequence
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>YSH1 YLR277C
CTTCTTCGGGCGATATACTTTTCAGCAACGGTGCTCATGACATGATCAACAATATTTCCA
CCTGGACCAATAACTCCGTTCTAGATGCTTTGAATAGCAAGTCCATACTACAAACAATAT
TTCCCCAGAGTCAAGAGCCTTCATCTCTGTCCATGGACAAACAGCAGCAACAACATCAAC
AACAAAATATGTGTTCTGAAAACAATGTAACCGCTAATAATTTTCAACAGACGCAGAATG
ACCCTTCGTATAACAGAAATTTGTTCATGATGTCCAATCAGGAAGGTGTACAATATAATC
TTGACGAAACAGAGAAGAATGGACCTAAAACACAGGTGGAAGCAAACACTAGCGCAAATC
TGCATTTCGACAATGTTATTCCTACAGTAACTAACGCAGACATCAGGAAAAAGCGTTCTA
ACTGGGATAACATGATGACATCTGGTCCGGTAGAAGACTTTTGGACGATTAATGATGACT
ACGGCTTTTTAACGTGATACTACATTAATATAATAGTATGTACAAACTCATTCCTTTTTT
TTTTTTTTTTTTTTTTCTCTTTTTTTTTAAAAGAACAACTAAATCGCTTTTTTTAATTAT
GATATGGGTCATATCTTATAAGCCTAATCTAAAACACATTTTTTTCTTTCATTTATATTG
TTTTTAAAATCAATAAAACTCTTTCTTTCCTGTATAAAGTCCTCTCCAAAAGACTAAGTA
GCGTGTTTGCAAATAAATACGGGTAAGCAGTTATTCTGGCCGAAAATTATGAAAAACTAG
CGGATCTTTAACAACTTCTACTGCTTCAGCGCAATACATATTGAGATCACATCTAATAGG
TTCAAAATGTTCACGGGTATAAGCGTTTATTTCTTTTACCCTTGTTTTCAGTACTTCAAA
AGTTACAGCACAAAAGAAACATTGTATTATCAATTGAATTTTGTCCATTGAGGAAATAAA
AAGTAACATAATAAGTTAACATTAATAAGTATACGCATAT
Chr coordinates
Chr XII from 699495-697156