Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
GCD7 Systematic Name
YLR291C Strain
S288c Description
Beta subunit of translation initiation factor eIF2B; the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as negative regulator of GCN4 expression; mutations in human ortholog EIF2B2 cause fatal brain disease childhood ataxia with central nervous system hypomyelination (CACH); human ortholog can complement yeast mutant, allows growth down-regulation of yeast gene External sources
Open in SGD
Open in KEGG
Gene Sequence
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Sequence hidden Promoter Sequence
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>GCD7 YLR291C
ATATCTTTGAACATAAAACCAATAGCCTTAAAATCAAAGAAACGTCTCCTTCAACTTGCG
TTAAAGGCATACCAAAGCAAGCTTATTCAACCATGGTTACCCTTGAATACAATGCAAACA
GTAAACTGATCACTGCGAGTGATGCTGTTGTTGCACTATCTACCGAAACTAATATCGATC
AAATAAATGTTCTCACTACATCTTTGATTGGAGAAACCAACCCAAATTTTACACCACAAC
CGAATGAAGCTCTAAGCAAAATGATCAAGGGTTTATTTGAAAGTGGTATGAAGAATTTAC
AACAAAAAAAATTGAATGAGGCATTGAAGAATGTTTCTTTAGCAATCGAAATGGCACAAA
GAAAAAGAGCGCCTTGGGAAGCTTTTGCTATTCAGCTACCAGAGCTACACTTTATGCTTC
GTAGTAAAATAGATTTATGTTTAATACTCGGAAAGCATTTAGAGGCGTTGCAAGACTTGG
ATTTCTTACTTGGTACGGGACTTATCCAACCAGACGTATTTGTCAGGAAGGCGGACTGTT
TGCTAAAATTGAGACAGTGGGAAGAGGCTAGGGCAACATGCGAGAGAGGTTTAGCTTTAG
CCCCAGAGGATATGAAACTTAGAGCCCTTTTAATAGAAACTGCAAGAAATCTGGCCGAAT
ATAACGGTGAATAAGGTGCATAACCGAAGATATTTTAGCCTTTTCTTGATATGTCTCTAT
GCTACACACGACTACATAGCAAGAAATTTTAGATAGATTCAAAAACACATAGCAAGCCCA
TTATCATATATACTAAGGAATAGCCTTTATGAAAGGCTTTGAACTATACAGCTTGAGTAT
ATGATACCTCTGCTTCCCAACCGCAAGCTTTTTTTCTTCGTGATGCTGAAAAAAAAAAAT
GGACATAGAAAAAACCTTCATAAATGAAACAGACCATTCATTACTCGTGCGGAACCAGTA
AACACAACACGCCAACTTTCGAACTTTTGCCCAACATAAG
Chr coordinates
Chr XII from 719462-718317
