Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
ACO1
Systematic Name
YLR304C
Alias
GLU1
Strain
S288c
Description
Aconitase; required for the tricarboxylic acid (TCA) cycle and also independently required for mitochondrial genome maintenance; component of the mitochondrial nucleoid; mutation leads to glutamate auxotrophy; mutation in human homolog ACO2 is associated with dominant optic nerve atrophy; human homolog ACO2 can complement yeast null mutant
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>ACO1 YLR304C
ATGCTGTCTGCACGTTCTGCCATCAAGAGACCCATTGTTCGTGGTCTTGCGACAGTCTCC
AACTTGACTAGAGATTCAAAAGTCAACCAAAACTTATTAGAAGATCATTCTTTTATTAAC
TACAAGCAGAATGTGGAAACGCTGGATATCGTAAGAAAAAGATTAAACAGGCCATTTACC
TACGCGGAAAAGATTTTGTACGGTCACTTGGATGACCCTCATGGTCAAGATATTCAGAGA
GGTGTTTCATACCTAAAATTAAGACCAGATCGTGTTGCCTGTCAAGATGCTACTGCTCAA
ATGGCTATTTTACAATTTATGTCCGCTGGTTTACCACAGGTTGCTAAGCCAGTCACTGTC
CACTGTGACCATTTGATTCAAGCACAAGTTGGTGGTGAAAAAGATTTGAAGAGAGCTATA
GATCTAAACAAGGAAGTTTATGATTTCTTGGCCTCTGCCACTGCGAAATATAACATGGGT
TTCTGGAAGCCAGGTTCCGGTATCATTCACCAAATTGTTCTGGAAAACTACGCTTTCCCA
GGTGCTTTGATCATTGGTACTGACTCCCATACACCAAATGCTGGTGGTTTAGGTCAATTG
GCTATTGGTGTTGGTGGTGCTGATGCCGTTGATGTTATGGCAGGTCGTCCATGGGAATTG
AAGGCTCCAAAGATCTTAGGTGTTAAGTTGACTGGTAAGATGAACGGTTGGACTTCTCCA
AAGGATATTATTTTGAAATTGGCTGGTATCACAACTGTCAAAGGTGGTACTGGTAAAATT
GTTGAATATTTCGGTGATGGTGTTGACACCTTCTCCGCTACTGGTATGGGTACCATTTGT
AATATGGGTGCTGAAATCGGTGCTACCACATCTGTTTTCCCATTCAACAAATCTATGATT
GAATATTTGGAAGCAACTGGTCGTGGTAAGATCGCTGACTTTGCTAAATTATACCACAAG
GACCTATTATCTGCTGATAAGGATGCTGAATACGATGAGGTCGTCGAAATTGACTTGAAC
ACTCTGGAACCATACATCAATGGGCCATTTACCCCCGATTTGGCTACTCCAGTTTCTAAG
ATGAAGGAAGTTGCTGTTGCTAATAACTGGCCATTGGATGTCAGAGTCGGTTTGATCGGT
TCTTGTACCAATTCCTCTTATGAAGATATGTCTCGTTCAGCATCCATTGTCAAGGATGCT
GCTGCTCATGGTTTGAAATCCAAGACCATTTTCACTGTTACTCCAGGTTCTGAACAAATC
AGAGCCACTATTGAACGTGATGGCCAATTAGAAACCTTCAAAGAATTTGGTGGTATCGTT
TTGGCAAACGCCTGTGGCCCATGTATTGGTCAATGGGATCGTAGAGATATCAAGAAAGGT
GACAAGAATACTATCGTTTCCTCTTACAACAGAAATTTCACTTCTAGAAATGATGGTAAC
CCACAAACTCATGCTTTTGTTGCATCTCCAGAATTAGTAACTGCGTTCGCCATTGCGGGT
GATTTGAGATTCAACCCTCTAACAGACAAATTAAAGGACAAGGATGGTAATGAGTTCATG
TTGAAACCACCACATGGTGATGGTTTGCCTCAAAGAGGTTATGATGCTGGTGAGAACACT
TACCAAGCTCCACCTGCAGACCGTAGCACCGTTGAAGTTAAAGTTTCTCCAACTTCAGAC
CGTCTACAACTGTTGAAACCATTCAAACCTTGGGATGGTAAGGATGCTAAAGACATGCCA
ATCTTGATTAAGGCCGTCGGTAAGACAACTACTGATCATATTTCTATGGCTGGTCCATGG
TTGAAATACAGAGGTCATTTAGAAAACATTTCTAATAACTATATGATTGGTGCTATTAAT
GCTGAAAACAAGAAGGCTAACTGTGTTAAAAATGTATATACTGGTGAATACAAAGGTGTT
CCAGACACTGCTAGAGATTACAGAGACCAAGGTATCAAGTGGGTTGTTATTGGTGATGAA
AACTTTGGTGAAGGTTCCTCTCGTGAACACGCTGCTTTGGAACCAAGATTCTTGGGCGGT
TTCGCTATCATCACAAAGTCTTTCGCTCGTATCCATGAAACTAACTTGAAAAAACAAGGT
CTATTGCCATTGAACTTCAAGAACCCAGCTGACTATGACAAGATCAACCCTGATGACAGA
ATCGATATTCTGGGTCTAGCTGAATTGGCTCCAGGTAAGCCTGTAACAATGAGAGTTCAT
CCAAAGAATGGTAAGCCATGGGATGCTGTGTTGACCCATACTTTCAACGATGAGCAAATT
GAATGGTTCAAATATGGTTCTGCCTTAAATAAAATTAAGGCCGATGAGAAGAAATAA
Promoter Sequence
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>ACO1 YLR304C
TTTTGGGTTTATTTTTGATATTGTCCCAGGTGGTATCAAGTTTGAAGCAGTACCATTCAA
GCTGACGAAAGAAATGGTTAAAGTGATGGGAGGTTCGCCCCAGACCCCAGCGTATCTGGA
CTTTGAAGAACTTTGTATCAAGGCATATCTAGCCGCCCGTCCGCACGTGGAGGCCATAAT
TGAGTGTGTAAATCCTATGTTAGGAAGCGGTCTCCCCTGCTTTAAGGGTCACAAGACAAT
TAGGAATCTAAGAGCAAGATTTCAACCTCAAAAAACCGATCACGAAGCTGCACTATATAT
GAAGGCGCTAATCCGTAAAAGTTATGAAAGTATATTCACTAAAGGTTATGATGAATTCCA
AAGGCTCACAAATGGCATTCCGTACTGATATACTTCGCACTTTACATATGCTTATATAAA
AATACCAGTTTCCCATCGTCAATTACGCAGACGTAGCCTTCGTTTATTTTCTCTCTTTTT
GTATATCATTGTATTAATCATAATCCATTGTATTTTACTTTGTCTTATCTGGCTTTAATG
AATGACGCCGGTCACACGCGGGTGCCTGATTCTCGATTGTGCCAAGCCATTTGGGCACGG
TGTCAAATTACCTAAAAAATGGCCGAGAGCCGCAAAAGGGAGGTCCGCGGGGCCGGGCAA
TACCCTTTGTTTTTCGAGCATTTCGGCGCCGAAATCGGCAAAGGTCCTGACCAATCAATA
GAGAAATTAGTGCATACGAGAAAAATTTGAACCCTTCAGTTGTTCTCCGCAGGCGACTTT
AACCATCAAACCTCCAATCGCTGCCGGTTTTCGGAAAGGCAAGCACAAAAAGGGAGGACA
AGGAAAATCTTTTGTTATATATATAATCTTCCGGTTTTAGAGGTTAATTAGGAGGAGTAT
GTTGCTTAATTCCGTTGTCCCTTGTTCTGTTCACTCTTTCTTAGTTATTACATAGTAGAA
CGAAGGTAATAAATACTACCATTATTACTATAGATATACA
Chr coordinates
Chr XII from 737548-735212