Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
EST2 Systematic Name
YLR318W Alias
TERT Strain
S288c Description
Reverse transcriptase subunit of the telomerase holoenzyme; essential for telomerase core catalytic activity, involved in other aspects of telomerase assembly and function; mutations in human homolog are associated with aplastic anemia External sources
Open in SGD
Open in KEGG
Gene Sequence
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>EST2 YLR318W
ATGAAAATCTTATTCGAGTTCATTCAAGACAAGCTTGACATTGATCTACAGACCAACAGT
ACTTACAAAGAAAATTTAAAATGTGGTCACTTCAATGGCCTCGATGAAATTCTAACTACG
TGTTTCGCACTACCAAATTCAAGAAAAATAGCATTACCATGCCTTCCTGGTGACTTAAGC
CACAAAGCAGTCATTGATCACTGCATCATTTACCTGTTGACGGGCGAATTATACAACAAC
GTACTAACATTTGGCTATAAAATAGCTAGAAATGAAGATGTCAACAATAGTCTTTTTTGC
CATTCTGCAAATGTTAACGTTACGTTACTGAAAGGCGCTGCTTGGAAAATGTTCCACAGT
TTGGTCGGTACATACGCATTCGTTGATTTATTGATCAATTATACAGTAATTCAATTTAAT
GGGCAGTTTTTCACTCAAATCGTGGGTAACAGATGTAACGAACCTCATCTGCCGCCCAAA
TGGGCTCAACGATCATCCTCATCATCCGCAACTGCTGCGCAAATCAAACAACTTACAGAA
CCAGTGACAAATAAACAATTCTTACACAAGCTCAATATAAATTCCTCTTCTTTTTTTCCT
TATAGCAAGATCCTTCCTTCATCATCATCTATCAAAAAGCTAACTGACTTGAGAGAAGCT
ATTTTTCCCACAAATTTGGTTAAAATTCCTCAGAGACTAAAGGTACGAATTAATTTGACG
CTGCAAAAGCTATTAAAGAGACATAAGCGTTTGAATTACGTTTCTATTTTGAATAGTATT
TGCCCACCATTGGAAGGGACCGTATTGGACTTGTCGCATTTGAGTAGGCAATCACCAAAG
GAACGAGTCTTGAAATTTATCATTGTTATTTTACAGAAGTTATTACCCCAAGAAATGTTT
GGCTCAAAGAAAAATAAAGGAAAAATTATCAAGAATCTAAATCTTTTATTAAGTTTACCC
TTAAATGGCTATTTACCATTTGATAGTTTGTTGAAAAAGTTAAGATTAAAGGATTTTCGG
TGGTTGTTCATTTCTGATATTTGGTTCACCAAGCACAATTTTGAAAACTTGAATCAATTG
GCGATTTGTTTCATTTCCTGGCTATTTAGACAACTAATTCCCAAAATTATACAGACTTTT
TTTTACTGCACCGAAATATCTTCTACAGTGACAATTGTTTACTTTAGACATGATACTTGG
AATAAACTTATCACCCCTTTTATCGTAGAATATTTTAAGACGTACTTAGTCGAAAACAAC
GTATGTAGAAACCATAATAGTTACACGTTGTCCAATTTCAATCATAGCAAAATGAGGATT
ATACCAAAAAAAAGTAATAATGAGTTCAGGATTATTGCCATCCCATGCAGAGGGGCAGAC
GAAGAAGAATTCACAATTTATAAGGAGAATCACAAAAATGCTATCCAGCCCACTCAAAAA
ATTTTAGAATACCTAAGAAACAAAAGGCCGACTAGTTTTACTAAAATATATTCTCCAACG
CAAATAGCTGACCGTATCAAAGAATTTAAGCAGAGACTTTTAAAGAAATTTAATAATGTC
TTACCAGAGCTTTATTTCATGAAATTTGATGTCAAATCTTGCTATGATTCCATACCAAGG
ATGGAATGTATGAGGATACTCAAGGATGCGCTAAAAAATGAAAATGGGTTTTTCGTTAGA
TCTCAATATTTCTTCAATACCAATACAGGTGTATTGAAGTTATTTAATGTTGTTAACGCT
AGCAGAGTACCAAAACCTTATGAGCTATACATAGATAATGTGAGGACGGTTCATTTATCA
AATCAGGATGTTATAAACGTTGTAGAGATGGAAATATTTAAAACAGCTTTGTGGGTTGAA
GATAAGTGCTACATTAGAGAAGATGGTCTTTTTCAGGGCTCTAGTTTATCTGCTCCGATC
GTTGATTTGGTGTATGACGATCTTCTGGAGTTTTATAGCGAGTTTAAAGCCAGTCCTAGC
CAGGACACATTAATTTTAAAACTGGCTGACGATTTCCTTATAATATCAACAGACCAACAG
CAAGTGATCAATATCAAAAAGCTTGCCATGGGCGGATTTCAAAAATATAATGCGAAAGCC
AATAGAGACAAAATTTTAGCCGTAAGCTCCCAATCAGATGATGATACGGTTATTCAATTT
TGTGCAATGCACATATTTGTTAAAGAATTGGAAGTTTGGAAACATTCAAGCACAATGAAT
AATTTCCATATCCGTTCGAAATCTAGTAAAGGGATATTTCGAAGTTTAATAGCGCTGTTT
AACACTAGAATCTCTTATAAAACAATTGACACAAATTTAAATTCAACAAACACCGTTCTC
ATGCAAATTGATCATGTTGTAAAGAACATTTCGGAATGTTATAAATCTGCTTTTAAGGAT
CTATCAATTAATGTTACGCAAAATATGCAATTTCATTCGTTCTTACAACGCATCATTGAA
ATGACAGTCAGCGGTTGTCCAATTACGAAATGTGATCCTTTAATCGAGTATGAGGTACGA
TTCACCATATTGAATGGATTTTTGGAAAGCCTATCTTCAAACACATCAAAATTTAAAGAT
AATATCATTCTTTTGAGAAAGGAAATTCAACACTTGCAAGCATATATATATATATATATA
CATATAGTTAATTAG Promoter Sequence
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>EST2 YLR318W
CTCCCTGAGTCTTTCGCCTACCGCACGGATGCCCACCATTACACTGTGGTCGATGGGTAG
CGAGTTTTCGCAGTTTCTGCCATCTTCTGCCACCACTTTGTCCTTCTTTCTTGATGGGTC
AACAAAGACGCTCACCATTGGAAACTGTTTTCCTGCCGTTGCCATCTTCACAGACAACGT
CGACGCACGCGATAGCTCATTTCGTACTTCCTGCATGTCTATTTTATAGTCGTTCAATAT
TTGATCATTGGGGTTGCCGTTCCAAATCAACGGCCAGTACTTCACAGACCAGGCATTGTT
CAGTTCCTTTGTGCTGGGCGCAAACTCAGGCACTTCGATATCATCACTCAGTTCATACTT
TTTCGTTCCAACCCAAATACTCTTCAATTTATTGTTTATTTCACCTTCGTCGCAAATATA
CTCTTTCGAACACAACACCACTTCCAAGGTGGAGGTCTCGATGTCCTTGCGGATCCTTTT
CAAATGTCTCAATGAAACAGGGTCATTTTTCTGAAAATCGTTTCGAATTAGCCTACTTTA
CTAGTTAGTTTACTTCCATGAATACAAAAGCAAAAATCATATACATACTCTATTACTTTC
TTCGAGTCTCTTGGATCTATTCTTATACTCCATACATTGACTGCACTTATATATGTTTGA
AAGTTAGTTAATTGATCCTGATTTCTGTTAGATCTCATAGATACATACTTAGTTTGGGCG
TATTTACATCTTTGAAATTTCTAATTTGCAGAAGCCGATTTTCTATTATCCCGTTCTGAT
AATCGATTTTTAGCGGATTATTAACTTTCTTAACCATAACTAACACGCCCTCATGAATAT
TATCCTTCTGAGGTTTGAATAATATATACCTTTAGATGAGCTATTGGTGATTCGCATTTA
GGAATGAAAAAAAGTAAAGCATGGCAATGAATGACACAAGTGAAATAGAAAAGTGAAAAA
TTAAAAAAAAAAAAAAAAAAAAAAAAACTGATTTATACTC
Chr coordinates
Chr XII from 766542-769196
