Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
SEN1 Systematic Name
YLR430W Alias
CIK3, NRD2 Strain
S288c Description
ATP-dependent 5' to 3' RNA/DNA and DNA helicase; subunit of the exosome-associated Nrd1p complex that mediates 3' end formation of snRNAs, snoRNAs, CUTs and some mRNAs; helicase-independent role in transcription-coupled repair; coordinates replication with transcription, associating with moving forks and preventing errors that occur when forks encounter transcribed regions; homolog of Senataxin, implicated in Ataxia-Oculomotor Apraxia 2 and a dominant form of juvenile ALS External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA Hide Seq
>SEN1 YLR430W
ATGAATTCCAACAATCCTGATAATAATAATAGCAACAACATTAATAATAATAATAAGGAT
AAGGATATTGCCCCCAATAGCGATGTTCAGCTAGCTACCGTCTATACCAAGGCAAAGTCT
TACATTCCTCAGATTGAACAAGTTTATCAAGGCACAAATCCAAATATTCAAGAGGCAAAA
TTATTAGGGGAGTTATTACAAGTTCTAGCAGAAGTTCCCAAGGGTACGCATTTATTTTGC
GACCCCATACTTGAACCAATATCAATTTTTTCCCTAACCATTTTCTCATTCAATGAAGAA
GCTACGGCCACATGGCTGAAGAATCATTTTAATCCAATTCTCTCTGTTTGTGATAAATGC
ATTCTAAATTTTGCGAGAGGGAAGTGCAAAATGTTACAACATTTTGCCATTCAAAGACAT
GTGCCGCATGAACATGTAGCCAAGTTTAATGACATCGTATGCCAATGGAGGGTGGAGGCT
GTTTTTCCTATTCTTAGAAATATTTCCGTTAACGATAATACGGGAATTAACATTACAAAT
GAAATTGAAACTGCAATGTACGAGTGTCTCTGTAATCCGCATATGTTGAGGCTTAACAAG
CAACTTAAGGCTACTTTCGAAGCAATCTTCAAATTTTTCTACGACACAAAGCATCGTTTG
TTGGACGTTACGAATCCATTAAGCATAAAAACCTTTATATCAGGTGTCATATTTTGCTGG
TGTGAAGGTTCAAAAGAGGAAAATGAGTGGTCACGAGCTTTTCTAAAGGATTTATACTCA
AGAAATTTCCATATAAATCTTTCTAACCTGACACCGGATATTATTGAGGAAGTTTATATC
CATATTTTATTCTTACAGAATCCGGCAAACTGGACAGAGATTGTGGTATCTCAATTCTGG
TCGAGATTACTACCGGTTTTCAATTTATTTGATAAAGACGTCTTCATAGAGTACTTTCAG
GTCCCAAAAAATGTGGAATCTTTAAAAAAAACATTCAAATTTCCGTTAGAGCCAATTTTT
AAAATGTGGTACAATCACTTAAGCAAATCATATCATGATAAGCCACTAGACTTTTTGTTA
AGAGGATTAACAATGTTCTTGAATAAATTTGGCTCCGAGTTTTGGTCCAAAATTGAACCC
TTCACATTCCATAGCATTTTGGATATAATTTTCAATAGAGATTCATTCCCAATCAAACTA
ATCAAAATTCAAGACAATCCAATTGTTGAGCATCAAACAGAAGTTTACTTTCAACTTACC
GGTTCTGTAACCGATTTACTTTCTTGGACCTTACCATTTTATCATGCACTGTCACCATCC
AAAAGAATTCAAATGGTTAGAAAGGTCTCAATGGCGTTCCTGCGTATAATAGCCAATTAT
CCATCCCTAAAATCCATTCCCAAAGCTTGTTTAATGAATTCAGCAACTGCCTTGTTGAGG
GCTGTGTTGACTATTAAGGAAAATGAAAGGGCAATGCTTTATAAGAATGATGAATTTGAA
ACAGTACTGTTGACTAAAACAGATTCTAGAGCTTTGCTCAACAATCCTTTGATCCAAGAC
ATAATAATTAGATCAGCTTCGAATCCTAACGACTTTTATCCTGGGCTAGGTGCTGCTTCT
GCATCGGTGGCCACATCCACGATGATGGTATTGGCAGAATGTATCGATTTTGATATACTG
TTATTATGTCATCGAACGTTTAAGCTTTATTCAGGTAAACCAATTAGCGAAATTCCAATT
TCAACCAACGTCTTGGAAAATGTTACAAATAAAATTGACCTGAGATCTTTTCATGACGGT
CCATTGCTGGCCAAACAGCTGCTAGTATCTTTAAAAAATATTAATGGTCTTTTGATAGTA
CCGTCAAATACTGCCGTAGCTGAGGCACACAACGCATTGAATCAGAAGTTTTTGCTGCTA
TCAACGAGATTAATGGAAAAATTTGCGGATATTTTGCCCGGTCAACTGTCTAAAATCCTT
GCGGATGAAGATGCATCGCAGGGTTTTTGGTCCTGCATATTCTCCTCTGATAAACACTTG
TATCAAGCAGCTACTAATATTTTATACAATACATTTGACGTTGAGGGTAGACTGGAAGGT
ATCTTAGCGATTCTGAATAGTAATTTGACCGTTAACTTGAAGAATATAAACGTGATGCTA
CAAAGATTAATCAATTGTGAATTCTATGAGCCTTGCCCCCGTGCTGTTCGTGTTTTGATG
GACGTAGTGAGTGCATTTGTAGACCCGATTTCTGGTGTGTTTGCTAATTTCCAAACTTTG
AAGAGCCAAAATACCGAAAAGGAATTTTTAAAATTCTGGGAATCATGTTGGTTATTCTTG
GATACGATTTATAAGTTTACTTTGAAATGGGCTTCTAAATATGACTATTCTGAACTGGAA
AATTTCACCAAAGATACTTTAGATCTAAGTCGCTCTTTGGTGGACTCCTTTAGAGAATTT
TCAGATATTCTTCATGACCAAACGAAAAATTTACTTCTCAACGTTTTAGAAACCTTTAAG
AATATGTTGTATTGGCTGAGATTGAGCGACGAAGTACTTTTGGAATCTTGTGTTAGATTA
ATTATAAGCACGTCTGATTTAGCACATGAAAAGCATGTGAAAGTGGATGATTCCTTGGTA
GAAATGATGGCCAAGTACGCCTCGAAGGCAAAGAGATTTTCAAATAAGTTGACGGAGCAA
CAGGCGAGTGAGATTCTACAAAAGGCTAAAATATTCAATAAAGCACTCACGGAAGAGGTC
GCTACAGAAGCTGAAAACTACAGAAAAGAAAAGGAATTATCAAGACTTGGGAAGGTGATC
GACTTAACGGATTCTGTGCCGGCGTCACCATCCCTCTCGCCCTCTCTGTCTTCAACCATT
GCTAGTTCTTCTGCTGAATCCAGGGCAGACTATTTACAAAGAAAAGCTTTATCTTCTTCA
ATAACTGGGAGACCAAGAGTAGCTCAGCCTAAAATAACATCTTTTGGTACGTTCCAATCA
TCAGCTAATGCTAAACTGCATCGTACAAAACCTGTTAAGCCTTTATCCAAAATGGAATTA
GCTAGGATGCAATTATTAAACAACAGAGTTGTTCATCCACCTAGTGCGCCAGCTTTCCAT
ACAAAGAGTAGGGGTTTGTCTAACAAAAACGACGATAGCAGTAGTGAGGAGAGTGACAAC
GATATAGAAAGCGCTCGGGAGCTTTTTGCTATTGCTAAGGCAAAAGGCAAAGGAATACAA
ACTGTCGATATTAATGGTAAGGTTGTCAAGAGACAAACTGCGGCTGAATTGGCTAAACAG
GAGTTAGAACATATGAGAAAGAGATTAAATGTTGATATGAACCCTCTATATGAAATCATA
TTGCAATGGGATTACACCAGAAATAGTGAATATCCTGATGATGAGCCTATTGGTAATTAT
TCTGACGTAAAGGATTTCTTCAACTCTCCTGCTGACTACCAAAAAGTCATGAAGCCTTTA
CTACTTCTAGAATCTTGGCAAGGTCTATGTTCTTCACGTGATAGAGAGGACTATAAACCT
TTCAGTATTATTGTAGGAAATCGAACTGCTGTGTCAGATTTCTATGATGTGTATGCCTCT
GTCGCTAAACAAGTCATACAGGATTGTGGTATTTCTGAATCTGACTTAATTGTAATGGCT
TATTTACCCGATTTTCGACCAGACAAAAGGTTGTCCAGTGATGATTTCAAGAAAGCACAA
CATACATGTTTAGCAAAGGTGAGAACATTGAAAAATACCAAAGGTGGTAATGTTGATGTC
ACATTACGAATTCATAGAAATCATTCTTTCAGTAAATTTTTGACACTAAGATCAGAGATA
TATTGTGTGAAGGTTATGCAAATGACGACTATTGAAAGAGAGTATTCAACACTGGAAGGG
CTGGAATACTATGACTTAGTTGGCCAAATTCTACAGGCTAAACCATCGCCTCCCGTAAAT
GTGGATGCGGCAGAAATTGAAACAGTTAAGAAAAGCTATAAGCTCAATACGTCGCAGGCT
GAGGCCATCGTTAATTCGGTATCTAAAGAAGGTTTTTCTTTAATTCAGGGTCCACCTGGT
ACGGGTAAAACAAAGACTATACTGGGTATTATTGGTTACTTTTTGTCTACAAAGAATGCC
TCATCTTCAAATGTCATCAAAGTGCCACTAGAAAAGAACTCATCGAATACTGAACAACTG
TTAAAAAAGCAAAAAATTCTAATCTGTGCCCCCAGTAATGCCGCTGTGGACGAAATCTGC
CTCAGACTGAAGAGTGGAGTGTATGACAAGCAGGGGCATCAATTTAAACCTCAATTGGTC
CGTGTAGGTAGGTCAGACGTTGTAAACGTTGCAATTAAGGACCTTACTTTAGAAGAACTT
GTGGATAAAAGGATAGGTGAAAGGAATTACGAAATCAGAACAGATCCGGAACTAGAACGT
AAATTTAATAATGCTGTGACTAAAAGAAGAGAATTGAGAGGAAAATTAGACTCTGAGAGT
GGTAATCCAGAAAGTCCAATGTCAACCGAAGATATCAGTAAATTACAACTTAAGATTAGG
GAGCTAAGTAAAATAATCAATGAACTTGGCCGTGATAGGGACGAAATGCGTGAGAAGAAT
TCCGTAAATTATAGGAATAGGGATTTGGATAGAAGGAATGCACAGGCCCATATCTTGGCG
GTTAGTGACATCATATGTTCGACTTTATCTGGTTCAGCCCATGATGTACTCGCAACAATG
GGTATTAAATTTGATACGGTCATTATAGATGAAGCATGTCAATGTACCGAACTTTCTTCA
ATTATTCCTCTCAGGTATGGAGGGAAGCGTTGTATTATGGTTGGTGATCCTAACCAACTA
CCACCAACTGTTCTTTCAGGTGCAGCAAGCAATTTTAAATACAATCAGTCACTGTTCGTT
AGAATGGAGAAAAATAGCTCCCCATACTTGCTGGATGTTCAATACCGTATGCATCCTTCC
ATCAGTAAATTCCCCTCTTCTGAATTTTATCAGGGACGACTAAAAGACGGCCCTGGTATG
GATATCTTGAACAAAAGACCCTGGCACCAGCTTGAGCCATTAGCTCCCTACAAATTTTTT
GACATCATTAGTGGTAGGCAAGAACAAAATGCGAAGACTATGTCTTATACAAATATGGAG
GAAATACGTGTTGCCATTGAGTTAGTTGACTACCTTTTCAGAAAATTCGATAATAAAATT
GATTTCACGGGAAAAATCGGTATAATTTCACCTTATAGAGAGCAAATGCAAAAAATGCGT
AAAGAGTTTGCCCGCTATTTTGGAGGCATGATCAACAAATCAATCGATTTCAATACAATC
GACGGTTTCCAAGGTCAAGAAAAAGAAATCATCTTGATATCGTGTGTCCGTGCCGATGAT
ACGAAATCTAGTGTCGGTTTTTTAAAGGACTTTCGTCGTATGAATGTGGCTCTGACTAGA
GCCAAGACAAGTATTTGGGTTTTGGGACATCAAAGGTCTCTGGCTAAAAGCAAGTTATGG
AGAGATTTGATTGAAGATGCAAAAGATAGAAGTTGTCTTGCATATGCTTGCTCGGGTTTC
CTGGATCCCAGAAATAATAGAGCTCAAAGTATTTTAAGAAAGTTCAATGTACCCGTACCA
TCAGAGCAAGAAGATGATTATAAGCTACCCATGGAATATATTACGCAAGGCCCCGATGAG
GTAAAATCCAATAAGGACACAAAGAAGAGAAGAGTTGTCGATGAAGGTGAAGAGGCAGAT
AAAGCTGTAAAGAAAAAGAAGAAAGAGAAGAAGAAGGAAAAGAAAAAGTCCAAGGCAGAT
GATAAGAAAAAGAATAACAAGAAGGCAGAATCGCCCAGCACCTCATCTGGTACAAAGAAA
AAGTCATCCATTTTTGGTGGAATGAGTGTACCGAGTGCCGTAGTTCCTAAAACTTTTCCT
GATGTGGACAGCAACAAAAAGGCAGCAGCAGTTGTTGGTAAAAAGAAAAATAACAAACAC
GTTTGTTTTTCGGATGATGTTAGTTTCATACCAAGAAATGACGAACCTGAAATTAAAGTG
ACCAGAAGTTTATCCTCTGTATTGAAGGAAAAGCAGTTAGGTTTGAAGGAGACGAGAACA
ATTTCTCCGCCTGAAATCAGTAATAATGAGGATGATGATGACGAAGATGATTATACGCCG
TCAATCTCCGATTCTTCATTAATGAAAAGTGAAGCAAATGGTCGTAACAACAGGGTGGCT
TCTCATAACCAAAATTTCAGCGCTAGTATATACGACGATCCACAAGTTTCGCAAGCAAAG
CAGACGCAGGTACCTGCTGCTATTACAAAACACAGAAGTTCAAATAGTGTTTTATCCGGT
GGTTCTTCGAGGATCCTGACTGCTTCCGATTACGGTGAACCCAATCAAAATGGACAGAAT
GGAGCAAATAGGACCCTCTCTCAACATGTGGGTAATGCGAATCAATACTCAACGGCTCCT
GTGGGTACAGGCGAACTGCATGAAACTCTGCCCGCCCATCCGCAAGACAGCTATCCTGCT
GAGGCAGAAGATCCATATGATTTAAACCCCCATCCGCAACCACAATCTTCAGCATTCAAA
GGACCTGGTAGTGGGCCCACAGGCACACGCAACAGTTCGAGACGGAATGCTTCATCTAGC
CCATTTATCCCAAAAAAAAGAAAGCCTAGATCATGA Promoter Sequence
Download FASTA
>SEN1 YLR430W
AAAGCTTACCTCAAGAAGAGAAGTCCTCTGAGAAAACAAAGTCCCCTGAGCAGGAAAAAT
CCGCAACACCTCCTTCTTCAATTACGGCTGCTAAGACAGCCATTACTGCCAGCAGTAAGG
AAGAGCCATCCGCGGCAAGGACATCACCTAAGTCATTGGGTTTAAAAAAGTCTGTCGAAA
AACTATCTACATTGGTTCTGCAATTAGAAGATGTAGTTGATAAATTAACGAAAGCAAATC
TTGACAAAGATGAGCGCCTGTTAAAGTTGGAACAAAAAATTGGCGAACTGTCAAAATGAA
AATTTTTTGTACTTTTAATGATAAAATTAAGTGAGTCCTTTTTATAGGAAAGATGTATTT
TGATTATATGTAATGTACATAAGACGGCGGCGATAATAATGCACTTAGAAAGTGAATCAT
GTTCACCTGTCCACTAACAAAAAAGGAAACAAAATGTTGCTTTCCCACAGGAAAAAGAAT
GTTTTTGACAAAACACTAAGCGTTATGTGACCAATGTATAATTGTCCTCATCATATAGTT
TTATGCAAGCATAAATAAGTCTTTCTTTTAGTTAAAACGCGTTACATAGTAAAGGTAACC
CTGAATGAATTTTTATTTATATTTTTCTTCGCATATTTTAGGATCTTGAAAAATTAACCA
CAAGTTAGAAGTTGATGAGATCAGGAATTCTAACAAAAGGTCATTGGTTAGGTTTATTTT
GTAGGTGCACGTTTGCAACTTTATTCCTTTTGTTTCAAAGTTATAGAGCTTTCATTTTCT
CATTCTTCTCTAGTGTAGGTCATTTCTCCTGCATATTAACCTACTAGAAAAGTTTACGAA
GCTTCATAGGAACGAATAATCGATCACTTTAAAGGCTTCCCGCACTTTAATCTTATCATC
TACACCTACAAAAAAGCTCTACTTTGTCATTTATTTTCTACTTCATCTCTGTATGGCATC
TATCTCTATATATATAAAAAAGCGCATCTGTTTATTATAA
Chr coordinates
Chr XII from 993434-1000129
