Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
LEU3
Systematic Name
YLR451W
Strain
S288c
Description
Zinc-knuckle transcription factor, repressor and activator; regulates genes involved in branched chain amino acid biosynthesis and ammonia assimilation; acts as a repressor in leucine-replete conditions and as an activator in the presence of alpha-isopropylmalate, an intermediate in leucine biosynthesis that accumulates during leucine starvation
External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA
View Seq
Sequence hidden
Promoter Sequence
Download FASTA
>LEU3 YLR451W
GTAGAAGAATATGGTTGGGAAGATATGGAAGTTGTCTCCGTATCTGGTAACTATTGTACT
GATAAGAAACCTGCCGCAATCAATTGGATTGAAGGTCGTGGTAAAAGTGTCGTAGCTGAA
GCTACTATTCCTGGTGATGTCGTAAAAAGTGTTTTAAAGAGCGATGTTTCCGCTTTAGTT
GAATTAAATATATCCAAGAACTTGGTTGGATCCGCAATGGCTGGATCTGTTGGTGGTTTC
AACGCGCACGCAGCTAATTTGGTCACTGCACTTTTCTTGGCATTAGGCCAAGATCCTGCG
CAGAACGTCGAAAGTTCCAACTGTATAACTTTGATGAAGGAAGTTGATGGTGATTTAAGG
ATCTCTGTTTCCATGCCATCTATTGAAGTTGGTACGATTGGCGGGGGTACTGTTCTGGAG
CCTCAGGGCGCCATGCTTGATCTTCTCGGCGTTCGTGGTCCTCACCCCACTGAACCTGGA
GCAAATGCTAGGCAATTAGCTAGAATAATCGCGTGTGCTGTCTTGGCTGGTGAACTGTCT
CTGTGCTCCGCACTTGCTGCCGGTCACCTGGTACAAAGCCATATGACTCACAACCGTAAA
ACAAACAAAGCCAATGAACTGCCACAACCAAGTAACAAAGGGCCCCCCTGTAAAACCTCA
GCATTATTATAACTCTTGTAGTTTACATGGTGATACTTTATATCTTTGTATTGTCTAGCT
ATTCTAAATCATCTGCATGTAATAAGAAGTTGATCAAAATGACTCGCTGCGTAAAACCTC
TCTTCGATCGGAGGTGCCGCCTAATTTATCGCCTAGCACTGCGCTTTTTCAAAGTTTTTC
AGAGCAAAAAATGAAAAGTAATGAGCACAACAATAGAAGAGTATCATGATATATAAGGTC
ATAAAACTAGGTTTCAGGGGCTATCGGCAATTTGAGGAACCTTCAACCTGCCTCAAGTAA
AAATCGCTTCGTAACATTAATACAAATTCTTTTTGCAATT
Chr coordinates
Chr XII from 1036093-1038753