Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
LEU3 Systematic Name
YLR451W Strain
S288c Description
Zinc-knuckle transcription factor, repressor and activator; regulates genes involved in branched chain amino acid biosynthesis and ammonia assimilation; acts as a repressor in leucine-replete conditions and as an activator in the presence of alpha-isopropylmalate, an intermediate in leucine biosynthesis that accumulates during leucine starvation External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA Hide Seq
>LEU3 YLR451W
ATGGAAGGAAGATCAGATTTTGTGGCGACTTCACAGTCCGGAAGTGAAATGAGCCATAGT
GAAACTAGGAATAGAACTGGGATGAATGCTAGGAAAAGGAAATTCGCCTGTGTGGAATGT
CGTCAGCAGAAGTCGAAATGTGATGCTCACGAAAGAGCACCGGAGCCATGCACTAAGTGT
GCTAAAAAGAATGTCCCATGCATTTTAAAACGAGATTTCAGAAGAACTTATAAAAGAGCA
AGGAACGAAGCCATTGAAAAAAGATTCAAGGAACTCACCAGAACTTTGACAAATTTAACT
TCGGATGAAATTTTGAAGAAAATTGAAGAGGAACAGGAAATTGTTTTGGATAACAGTAAT
TTCACAAAAGAAAAAGTAAAACAACTCAGGAAGAGTGCTTTTGAGACGACAGAAATAGAA
CCGAGATCATACAAAACACTTCGAGGAGAACCTATTTCTTACAGTACCAACAGAAGACAT
ACGGATTCTTCTCCTTTAACGCTCTTAAGCTCGTCGACAAACTTCGACCCTGTTCACTCA
ACAAACGTTATGACAGATGATCAACTTAAGTGCTTGCCAAAAAGCCTGGGCGACGTATAT
TTGTCAAGCAGCGATATTGCTGAGCTGTTTCAAGAATTTGCGACAAAATATCATCAATTT
TTACCCGTCGTTGACCTTTCGAAAGGAGCAGAGCGAATTTATCACTTATCTCCTTGCTTA
TTCTGGGTCATCCTGCTCATTGGTTTAAGGCGGAAATTTGGGGCTACAGACTTAATGACT
CGATTATCAGTGCTAGTAAAGTCAGTTTTATCAGAAATCACAATATCTCCAATAATTCGA
TATACTCCATCAGATAAGGACGAACCCGTTCTAAATGTAGCATCTGTATATTCCGTGCAA
GCATTTCTTTTATACACGTTCTGGCCTCCCTTAACCTCTTCATTAAGCGCCGACACTTCG
TGGAATACCATAGGAACAGCGATGTTCCAAGCGCTTCGGGTAGGACTAAATTGTGCAGGT
TTTTCAAAAGAGTATGCTTCGGCAAATTCAGAATTAGTTAACGAGCAAATACGAACTTGG
ATTTGCTGCAATGTTGTATCTCAAACAGTTGCATCATCATTTGGTTTCCCAGCTTATGTT
TCATTTGATTATTTAGTAATCAGCTCTATTAGAGTACCAAATTCAAAAAGCCAAGTAGAT
ATACCCAATGAACTAAGACAAATGGCTCAAATTGCTAGATTTGAGAACCAAATCGTAAAC
ACAATGAACTCCACCCCGGCGAGTGTTACTGGGATGGTAAGTCAGGAAGAGAAGCAGCCC
TTGTTACACGTTCTTAATCAACAACTAAGTCAATTGGAGATTAGTCTTGAAGAAAATAAC
CTAGATGATATCCGAAAATTTTTATTACTAGTGGCCAAGGTTCACTTATTAACCTATTAC
TTCACTGATGTTACCTCCCAAAGTGCTGGAAAATCAAATGGTAATATTTATGAGGGATCA
TATTCCATTATGGAACTCGATACAAGTTTTGAAACGAAACGTGGATTGGTGAAAGTTTAT
AATGCCGCCGTAAACTTTCTTATACATGCCAATAGTATGTGGGAACATGATCCTACCATT
ATTAAGTACTTTCCTGGTTTGTTTGTCTTGAATATATGGCAATCTGCCTGTATTATTAGT
AAACTCATACATTCATCACTTCATTCAATGCTAGATGTTAACTCAGGCAAAAAAGCTTAT
AACAACGCAATTTCATTGACGTTTAATGCCTCAGTTTTAAAATATGATATGGCGTACAGA
TCATCCGGAATAATGCGAAGCATATGGAGTTTATTTGCTAATATGTATGATGCCTGGAAA
AACGACCAAAAGGAAGGTGGAGGTAGACTAAATAATGATTTCAATTTAGGCATCACCATA
AAATCTAGGATGTCAGTAAACGTTTTTTTTGACTGCTTATATATTCTAAAAGAGAAATGT
GGTATGGCCAAATTGGAGAGAGAGACCAAGGTTTCTACAGCTTACAATGTTGATGAAGAG
GAAGAGGAAGATGAAGATGAGGAGGGAGAAGAAGAAGAAGAAGAAGAAGAACTAAGTAGT
AAAGTTCCAGAAAATATGGATAGCCAGCAACTAAGGACAAGGAAATTCACCAATGTAAGG
CATCCAGAAAAGAAAGCAAGAAAAATAATTGAAACAATTCCGCTAGACCCAAATCCAATA
AATGCAGGCTCTACCAGCAGTGGAAGCTCATTAACGACCCCAAATAGTCAAGTAGCGAAC
ACTATATCATATAGAGGAATCCTCAATAAAATGTCACCTAGGGAACAACTGAATCATGCA
AATTTAGATTCCAGTGTTTCTACAGACATCAAGGACACTGAAGCTGTCAATGAACCTCTG
CCAATAGGGAGGAATGCTGAACATCCGGCAAATCAACCGCCTCTTTCAATAACACAAATG
CAAGAAAACACACTACCTGCGACACAAGCCAACTCTTCTCTATTAGAAACGTATCCCATT
GTTCAATCAAACCCCGTTACAACTACAATCAAAGAATCACCCAATTCCATCATGGCAGGT
TGGGATAACTGGGAATCTGATATGGTTTGGAGGGATGTTGATATTTTAATGAATGAATTT
GCGTTCAATCCCAAGGTTTAA Promoter Sequence
Download FASTA
>LEU3 YLR451W
GTAGAAGAATATGGTTGGGAAGATATGGAAGTTGTCTCCGTATCTGGTAACTATTGTACT
GATAAGAAACCTGCCGCAATCAATTGGATTGAAGGTCGTGGTAAAAGTGTCGTAGCTGAA
GCTACTATTCCTGGTGATGTCGTAAAAAGTGTTTTAAAGAGCGATGTTTCCGCTTTAGTT
GAATTAAATATATCCAAGAACTTGGTTGGATCCGCAATGGCTGGATCTGTTGGTGGTTTC
AACGCGCACGCAGCTAATTTGGTCACTGCACTTTTCTTGGCATTAGGCCAAGATCCTGCG
CAGAACGTCGAAAGTTCCAACTGTATAACTTTGATGAAGGAAGTTGATGGTGATTTAAGG
ATCTCTGTTTCCATGCCATCTATTGAAGTTGGTACGATTGGCGGGGGTACTGTTCTGGAG
CCTCAGGGCGCCATGCTTGATCTTCTCGGCGTTCGTGGTCCTCACCCCACTGAACCTGGA
GCAAATGCTAGGCAATTAGCTAGAATAATCGCGTGTGCTGTCTTGGCTGGTGAACTGTCT
CTGTGCTCCGCACTTGCTGCCGGTCACCTGGTACAAAGCCATATGACTCACAACCGTAAA
ACAAACAAAGCCAATGAACTGCCACAACCAAGTAACAAAGGGCCCCCCTGTAAAACCTCA
GCATTATTATAACTCTTGTAGTTTACATGGTGATACTTTATATCTTTGTATTGTCTAGCT
ATTCTAAATCATCTGCATGTAATAAGAAGTTGATCAAAATGACTCGCTGCGTAAAACCTC
TCTTCGATCGGAGGTGCCGCCTAATTTATCGCCTAGCACTGCGCTTTTTCAAAGTTTTTC
AGAGCAAAAAATGAAAAGTAATGAGCACAACAATAGAAGAGTATCATGATATATAAGGTC
ATAAAACTAGGTTTCAGGGGCTATCGGCAATTTGAGGAACCTTCAACCTGCCTCAAGTAA
AAATCGCTTCGTAACATTAATACAAATTCTTTTTGCAATT
Chr coordinates
Chr XII from 1036093-1038753
