Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
HUG1
Systematic Name
YML058W-A
Strain
S288c
Description
Ribonucleotide reductase inhibitor; intrinsically disordered protein that binds to and inhibits Rnr2p; involved in the Mec1p-mediated checkpoint pathway; transcription is induced by genotoxic stress and by activation of the Rad53p pathway; protein abundance increases in response to DNA replication stress
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>HUG1 YML058W-A
ATGACCATGGACCAAGGCCTTAACCCAAAGCAATTCTTCCTTGACGATGTCGTCCTACAA
GACACTTTGTGCTCAATGAGCAACCGTGTCAACAAGAGTGTCAAGACCGGCTACTTATTC
CCCAAGGATCACGTTCCTTCTGCCAACATCATTGCCGTCGAACGTCGCGGCGGTCTTTCT
GACATTGGTAAGAATACTTCCAACTAA
Promoter Sequence
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>HUG1 YML058W-A
CGGGTGGCGCGTTGGCTGACTGAGTGGAAGCTGCATTGATATTGGCGCTGGAGCCAGATT
TACCTGTATTTTCCAGCGGCAAGAACTCCGGGGTCAGCCTCTTGTACTGGGATAGAATTC
TCTCCTTCATGATGGTGTAAGTCACAAAGACTATGACGGCTAGGGCAAACAGGATCAGCC
AAAAGGAAAGAGTGAACTGAACATGGTGTAACTTGAAGAAGATCCACTTCGGAATCCTTA
AAAGCGATAAAGTTGCCAGATACCAACCGTACCTGAAGATCATACGAGAGGCACCCATAA
CAAAGTAGGACACAACCCACGAGAAGTTGAAGAGGGATGAAAGTGACCACGTCTGCGCCT
CAGAAATAATCTGGTCGGTGAGACATGTCTGGAATCTATAAGAAGTATAATTACTGGAAT
TAAAGCTGGAGCCAAGACTGTTTTTCGTGTTTTGGCCGGTATTGTTGGTGTTGTTCGTAG
TGCAATTCATTGAACGCATGCAAAAACTAGAGCCAAGCCTTTCTATTCTTTTCTTGTTTA
TTTTATATTCGTTAGAGTTTTGTGGTGTTTCTTTAACTTAATAAACTTTCGAGAAAAGTG
TCAAGTTTCCCAGATTTTTAAGATCCTTATAACCTGTAAAAAAAAAAAAAAAAAAAAAAA
AGAAGGGTTTAAATAAAAATCGGACTTACTCAAAGGGTTGAAAAGCACTTTAATATAGGT
TTTTAGTTTCGGGTAAGAAGATGTGTCAAAGGTCTCGAAAAGGAAACATTAGGGCAAATA
CGTAAAGGTTGCCTTCGTATCTCGTTTCCACAGCAACGAGAAACGAGATACGAAGGCAAC
TGATTCCCAGCATATAAAAGGCCATGAATTTTTGGCGTTTCCTATTGTCTTTTCGAAACT
ATTTCTTTCATTCCTTTCCTTTCTTGTTCTTTTACTTATAAGAAAAATAATATACGTATA
TATATAACTACAAACCACATCAGCAATAAAAAAAAACTAT
Chr coordinates
Chr XIII from 158760-158966