Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
PIF1
Systematic Name
YML061C
Alias
TST1
Strain
S288c
Description
DNA helicase, potent G-quadruplex DNA binder/unwinder; possesses strand annealing activity; promotes DNA synthesis during break-induced replication; involved in crossover recombination; works with Hrq1p to maintain telomere length homeostasis; translation from different start sites produces mitochondrial (DNA repair and recombination) and nuclear (catalytic inhibitor of telomerase) forms; mutations affect Zn, Fe homeostasis; regulated by Rad53p-dependent phosphorylation in rho0 cells
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>PIF1 YML061C
ATGCCAAAGTGGATAAGATCAACATTGAATCATATTATACCAAGAAGGCCATTTATCTGT
AGTTTCAACAGTTTTCTTTTACTCAAAAACGTATCGCACGCCAAACTATCGTTTTCTATG
AGTAGTCGTGGTTTCAGGTCTAATAACTTTATTCAAGCACAATTGAAGCATCCTTCCATA
CTTTCAAAAGAAGACCTAGATTTGCTCTCTGATTCGGATGATTGGGAAGAACCTGATTGC
ATACAGTTAGAAACTGAGAAGCAAGAAAAGAAAATTATCACTGACATACATAAAGAAGAC
CCGGTGGACAAAAAGCCTATGAGGGATAAAAATGTCATGAATTTTATCAATAAAGACAGT
CCTTTATCCTGGAACGATATGTTTAAACCCAGTATAATACAACCACCGCAGTTAATTTCT
GAAAACTCATTTGACCAGAGCAGTCAAAAAAAATCGAGATCGACAGGATTCAAGAATCCA
TTAAGACCAGCGTTGAAAAAGGAAAGTTCTTTTGATGAACTTCAAAATAATTCTATATCT
CAAGAGAGAAGTTTGGAAATGATAAATGAAAACGAAAAGAAGAAAATGCAATTTGGAGAA
AAGATTGCTGTTTTGACGCAAAGACCTAGCTTCACTGAATTGCAGAATGACCAAGATGAC
AGTAACTTGAATCCCCATAATGGTGTGAAAGTCAAGATACCGATTTGCTTAAGCAAAGAA
CAAGAAAGTATCATCAAGTTGGCAGAAAATGGCCACAACATTTTTTATACAGGGAGTGCC
GGTACCGGTAAATCCATTCTTTTACGTGAAATGATAAAAGTTTTAAAAGGCATATATGGT
AGGGAGAATGTTGCAGTCACTGCTTCCACGGGTTTAGCTGCTTGTAATATCGGTGGTATA
ACCATACACTCGTTCGCTGGTATAGGATTAGGAAAAGGTGATGCGGATAAACTCTATAAA
AAAGTTCGTAGGTCTCGAAAGCACCTAAGGCGCTGGGAAAATATTGGTGCTTTGGTTGTC
GATGAAATATCAATGTTAGACGCAGAACTGCTTGATAAACTCGATTTCATAGCTAGAAAA
ATACGGAAAAATCATCAACCCTTCGGTGGAATTCAACTCATCTTCTGTGGCGATTTTTTC
CAGTTACCGCCAGTATCAAAAGATCCTAATAGACCAACTAAGTTTGCTTTCGAATCCAAG
GCTTGGAAAGAAGGTGTAAAGATGACGATTATGCTACAAAAGGTTTTTAGACAGCGAGGC
GATGTTAAGTTCATTGACATGTTGAATCGGATGAGACTAGGCAATATTGATGATGAAACA
GAAAGAGAGTTCAAGAAGCTTTCTAGACCATTGCCAGACGATGAAATTATTCCCGCGGAA
CTTTATAGTACCAGAATGGAAGTAGAAAGGGCCAATAATTCAAGGCTAAGTAAATTGCCA
GGCCAGGTGCATATTTTTAATGCAATCGATGGCGGTGCTTTGGAAGACGAAGAGTTAAAG
GAAAGGCTGTTACAAAATTTTTTAGCTCCAAAGGAATTACATTTGAAAGTTGGCGCTCAG
GTTATGATGGTAAAAAATCTAGACGCAACATTAGTTAATGGATCCCTTGGTAAAGTCATC
GAATTCATGGATCCAGAAACATATTTTTGCTATGAGGCGCTAACAAACGATCCATCTATG
CCTCCAGAAAAACTCGAGACTTGGGCAGAAAACCCTTCAAAACTAAAAGCTGCAATGGAG
AGGGAGCAAAGTGATGGGGAAGAAAGTGCGGTAGCTAGTCGCAAATCTTCAGTGAAGGAG
GGATTTGCTAAGAGTGATATAGGTGAGCCGGTCTCTCCCCTAGATTCCTCAGTTTTTGAC
TTCATGAAGAGAGTCAAGACAGATGACGAAGTTGTGCTGGAAAATATAAAACGCAAGGAA
CAACTGATGCAGACCATACATCAAAACTCTGCAGGAAAACGAAGGTTACCTCTCGTGAGA
TTCAAAGCTTCTGATATGAGTACGAGGATGGTGCTTGTCGAGCCGGAGGATTGGGCGATA
GAAGACGAAAATGAAAAGCCACTGGTATCAAGGGTTCAATTACCGCTAATGCTTGCCTGG
TCACTATCCATTCACAAATCTCAGGGTCAGACACTTCCAAAAGTTAAAGTGGATTTACGT
AGAGTATTCGAAAAGGGTCAGGCGTACGTTGCCCTTTCTAGAGCTGTTTCAAGAGAAGGA
CTACAGGTGTTAAATTTTGACAGAACTAGGATCAAAGCACATCAAAAGGTAATTGATTTT
TATCTTACTTTATCTTCAGCCGAAAGTGCCTATAAGCAACTTGAGGCAGATGAGCAAGTG
AAAAAAAGGAAGTTAGACTACGCACCAGGCCCTAAATATAAGGCTAAATCCAAGTCAAAG
TCAAATTCTCCAGCACCCATATCAGCGACCACACAATCTAATAATGGTATCGCAGCGATG
TTGCAAAGACACAGTAGGAAGAGATTTCAGTTGAAAAAAGAGTCTAATAGTAATCAAGTT
CATTCATTGGTTTCCGACGAACCTCGTGGTCAGGATACCGAAGACCACATCTTAGAATAA
Promoter Sequence
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>PIF1 YML061C
TTACAGATACTTTGAAGGTATGTGGTGTCAGAAGTAATATTAGCTTCAGCTTTATCATTC
ACCAGTTTTCTCGCGGTTTCGATAATATACTTAGCTCTATATCCAAAGCCCAGCTCACGC
AACTTGGCTTCAGTGGCTCGAGAAGTTAGCTCCTCACTTGTAGGAAACGAATGGTAGGCG
ACCCCATCTATTGTTGTGATTAAGTTCCCGAAATTAGAGCAAAGGCTATTGCACATTCTC
GTAATTCTTGAAATGTTATTATTACTCGAGCAAATAAAGGAAATCAATGTCTCCCATGGT
TCCTGGGCCAAGATACGGATGCCTTGTGGAGAAAGTTTCGCAAATGCTTTATCGCTTGGA
ATCCAAACATTATCGAATAAGTGCTTCAGTGACACGTCCAATCTAAAATATTTCATTAGA
TGAGTTTTTAAGGCGTCCTGATTGCCACAGTCGCCGACAGCAACAAATTCCAGGATCTCA
TTCTCTTCATCTTGCCTCAAAATCACTACTGAATACTTTTCTTGCTGGCCTATCTTCATT
GTAGTGCTGTACTGGTTTAACTTTTCATCCCAAATCCATCGAAAGGATTGGCCAGCCTGT
AGCACATTTGCTAGACATAGCTCACTTTTATTAATGGCAAGTTTGCCGAATTTATAAGAC
ATCTGGTTGATAAATAAAATCGCAATTATGAATCAGGACGCTTCAAATGCCTTCTTCCGC
TGGAAATAGTAGTTTTGTGATGCTGTTCAGCTCATCTCTTAAAAATTTTTGGCGTTACAT
TAAGAAAGGCGCGTCTTAATTTTCTTCACTTAATGTATAAACAAATACTTTACTTTTTAA
CCACGACATTATTCAAAGAGGAGAGTAACTTTAACGTTAATCAAATTGCTGTACTAAACT
ATTTATTTGGCCAGACATTGAAATACTGGTATTGCCTCGATATTTTTATTTGTAATATTA
TCCATTGAGCGATTAGCTTACTTGTATCAATCAATTTTAC
Chr coordinates
Chr XIII from 151532-148953