Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
ERO1 Systematic Name
YML130C Strain
S288c Description
Thiol oxidase required for oxidative protein folding in the ER; essential for maintaining ER redox balance; feedback regulated via reduction and oxidation of regulatory bonds; reduced Pdi1p activates Ero1p by direct reduction of Ero1p regulatory bonds; depletion of thiol substrates and accumulation of oxidized Pdi1p results in inactivation of Ero1p by both Pdi1p-mediated oxidation and autonomous oxidation of Ero1p regulatory bonds; ero1-1 mutation complemented by human ERO1L External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA Hide Seq
>ERO1 YML130C
ATGAGATTAAGAACCGCCATTGCCACACTGTGCCTCACGGCTTTTACATCTGCAACTTCA
AACAATAGCTACATCGCCACCGACCAAACACAAAATGCCTTTAATGACACTCACTTTTGT
AAGGTCGACAGGAATGATCACGTTAGTCCCAGTTGTAACGTAACATTCAATGAATTAAAT
GCCATAAATGAAAACATTAGAGATGATCTTTCGGCGTTATTAAAATCTGATTTCTTCAAA
TACTTTCGGCTGGATTTATACAAGCAATGTTCATTTTGGGACGCCAACGATGGTCTGTGC
TTAAACCGCGCTTGCTCTGTTGATGTCGTAGAGGACTGGGATACACTGCCTGAGTACTGG
CAGCCTGAGATCTTGGGTAGTTTCAATAATGATACAATGAAGGAAGCGGATGATAGCGAT
GACGAATGTAAGTTCTTAGATCAACTATGTCAAACCAGTAAAAAACCTGTAGATATCGAA
GACACCATCAACTACTGTGATGTAAATGACTTTAACGGTAAAAACGCCGTTCTGATTGAT
TTAACAGCAAATCCGGAACGATTTACAGGTTATGGTGGTAAGCAAGCTGGTCAAATTTGG
TCTACTATCTACCAAGACAACTGTTTTACAATTGGCGAAACTGGTGAATCATTGGCCAAA
GATGCATTTTATAGACTTGTATCCGGTTTCCATGCCTCTATCGGTACTCACTTATCAAAG
GAATATTTGAACACGAAAACTGGTAAATGGGAGCCCAATCTGGATTTGTTTATGGCAAGA
ATCGGGAACTTTCCTGATAGAGTGACAAACATGTATTTCAATTATGCTGTTGTAGCTAAG
GCTCTCTGGAAAATTCAACCATATTTACCAGAATTTTCATTCTGTGATCTAGTCAATAAA
GAAATCAAAAACAAAATGGATAACGTTATTTCCCAGCTGGACACAAAAATTTTTAACGAA
GACTTAGTTTTTGCCAACGACCTAAGTTTGACTTTGAAGGACGAATTCAGATCTCGCTTC
AAGAATGTCACGAAGATTATGGATTGTGTGCAATGTGATAGATGTAGATTGTGGGGCAAA
ATTCAAACTACCGGTTACGCAACTGCCTTGAAAATTTTGTTTGAAATCAACGACGCTGAT
GAATTCACCAAACAACATATTGTTGGTAAGTTAACCAAATATGAGTTGATTGCACTATTA
CAGACTTTCGGTAGATTATCTGAATCTATTGAATCTGTTAACATGTTCGAAAAAATGTAC
GGGAAAAGGTTAAACGGTTCTGAAAACAGGTTAAGCTCATTCTTCCAAAATAACTTCTTC
AACATTTTGAAGGAGGCAGGCAAATCGATTCGTTACACCATAGAGAACATCAATTCCACT
AAAGAAGGAAAGAAAAAGACTAACAATTCTCAATCACATGTATTTGATGATTTAAAAATG
CCCAAAGCAGAAATAGTTCCAAGGCCCTCTAACGGTACAGTAAATAAATGGAAGAAAGCT
TGGAATACTGAAGTTAACAACGTTTTAGAAGCATTCAGATTTATTTATAGAAGCTATTTG
GATTTACCCAGGAACATCTGGGAATTATCTTTGATGAAGGTATACAAATTTTGGAATAAA
TTCATCGGTGTTGCTGATTACGTTAGTGAGGAGACACGAGAGCCTATTTCCTATAAGCTA
GATATACAATAA Promoter Sequence
Download FASTA
>ERO1 YML130C
TTACTGCCATTATGTAGGCCTTTTGAGTCAGCTTTGTGAAGAGATCTTATTACCTTAATT
CTTGCTGAAAAATACATCGCAATGAAGTCACTTTCGTGATGGAAAGAACACGGCGGTAAG
AATACGTTCCTTTTTGTGCTGTGTACACCCGTAAAATTGTACATTATTTATTTCAAAATA
TATAACAGGATCCCTCCAGTGTGTCTGAAATGATGCAACTCTGATACTTCAGAGTCGTAC
CCTTATTAAATACTAATGCCGAATATAGTCATCCAGTAGCCATAGTTCACACACACATTA
CTTATTCACCACATAAAGAACTAGAAATGCTTGCTAAATATCGTACCTTGAAGGTAAACA
TTAAGGCCCCCCAAAAGCATATATACATACTGGCAACACAAAAAAAGTAAATTGCCAACC
ACCTACCTTACATATGGTTTGCCCATCCTACATTACCAATACTATCAAGACATTTCTTCT
GAAACATATTCACAACTGAAACGAGATCATTTTCTTATCTATCTATTGAGTAATGCTTAC
TTTTCATATTTTCAATGAACAATAGGATATGTAGGAGAATTGATATATTCACTGCGTATC
AGAGAAAAGGTCTACTGACATTTTATGGCAAATGTATTCTACACAAATCGAGAATACCAC
AGACAATGGTACAAGACATACACAAAGAGAAGACTGTTCTAATTAAACAAATAATATTGA
GCTACCTGCTAAGTATGTCCTTTTCCCTTTGTCCTTTGGTTTCTCTTATAGAAGACCCTG
GAAATTTTTCGCATTTTTCCGGCTTTGGGCGTTAGTAAGAACAAAAAGAAAAGAAGAGAA
CAAAAAAGAAACGATACGGAGTACGTGTCATAAAAACTTGTTCAATCATCCTTGAAGCTA
AGTATAAAGAGCTTGAAAAGGTTTACCACTTAAACTGGTTATACTATTTCAAGAGTGTAA
ACATTTTATTGCATATACCACAGTAACGTGCAGGTAAAAC
Chr coordinates
Chr XIII from 13174-11483
