Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
COS3
Systematic Name
YML132W
Strain
S288c
Description
Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>COS3 YML132W
ATGAAAGAGAATGAACTTAAAAATGAGAAGAGTGTAGATGTATTATCCTTCAAACAGCTC
GAATCCCAAAAGATTGTTCTACCTCAAGATCTTTTCAGAAGCAGCTTTACCTGGTTTTGT
TATGAAATTTACAAGTCCTTAGCGTTTCGCATCTGGATGCTATTATGGCTACCACTTAGC
GTCTGGTGGAAACTTTCCAACAATTGTATTTACCCACTTATAGTTTCACTTCTGGTCCTG
TTTCTGGGACCAATATTTGTCCTTGTTATTTGTGGACTTTCTCGTAAGCGTTCCTTATCG
AAACAACTCATTCAGTTTTGCAAAGAGATTACTGAAAACACACCAAGTTCTGATCCTCAT
GATTGGGAAGTTGTTGCAGCAAATCTAAATTCGTACTTATATGAAAATAACGTTTGGAAT
ACTAAGTACTTTTTTTTCAATGCCATGGTCTGTCAAGAAGCGTTCAGAACAACCCTTCTC
GAACCATTTTCTTTGAAAAAAGATAAAGCTGCCAAGGTTAAGTCATTTAAGGATTCCGTC
CCTTACATTGAAGAAGCATTGGGAGTTTATTTTACAGAAGTTGAAAAACAATGGAAATTG
TTTAATACTGAAAAATCATGGAGCCCTGTTGGCCTGGAAGATGCTAAACTTCCCAAGGAA
GCTTACCGATTTAAGCTTACTTGGTTTTTAAAGAGGATTTCCAATATTTTTATGTTGATA
CCATTCCTTAATTTTTTGTGCTGCATATATGTGTCACGGGGAATGTGCCTTCTATTACGC
ACCTTGTATCTCGGGTGGATTCTTTTCATGTTGGTACAAGGTTTCCAAAATATAAGGGTT
TTGATTATGAGCATGGAACACAAGATGCAGTTCTTGTCGACTATTATAAATGAGCAAGAA
AGTGGTGCGAATGGATGGGACGAAATTGCAAGGAAAATGAATAGGTACTTGTTTGAGAAA
AAAGCCTGGAAGAATGAAGAGTTTTTCTTCGACGGGATTGACTGTGAATGGTTTTTTAAC
CACTTCTTCTACCGCGTTCTATCTGCGAAGAAATCTATGTGGCCTTTACCATTGAATGTG
GAACTATGGCCATACATTAAAGAAGCGCAATTATCCCGCAGTGAGGTGCTCTTAGTGTAG
Promoter Sequence
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>COS3 YML132W
AATTTATATACACTTATGCCAATATTACAAAAAAATCACCACTAAAATCACCTAAACATA
AAAATATTCTATCCTTCAACCATAATACATAAACACACTTAATTGCGTCTTAATACTATC
ATGGTATCATTAACTTAAAGTTCCTTAATATCGTCATACCACTATGCTCTATTCCATATA
TTGTAATATAACTGTACTCTATAGTCATACAGACGCTTTTACTTCACCCCATCTTATACT
ATTGTCATAGAATCTCACACTGACGCATGATTAAAACGAATAATTTTTACTGTAAGGGCT
GCCATCCGCGCTCTATCCTTTTGTTTGCAATATTTATATACAGAATCTCAAAACAAGCGG
GAGAAGTGCTAATTACCCAGAGGTCATGCATGATCTGAGTACCACCGTACCTCTAGGTTT
TGCTTTGATCCGTTTTACAGTGACACCGAACATAAGGGGAAGCTATTGACATGGTATCGA
AAGGTTGTCCACATTGGGAAGTAACTTGGTTCTATGAATCTTCATGTCAGATACGTAGGA
CAGACTCTTTCCTGTGTAAATATTTGTGACAGCTACGTCTATTTTCTACTAGATGTTTAC
ACAGTTTTGTCACAGGAAATCTACGCTTAAAATATGTATTTCATTCAAGCGGTAACCGCT
GTACGAGCAGTGACATTGCTGGTCGCACCCTAAATGTGAACCAACGTTACGGCACACCGT
GATGTACCCGCATTAAAGTTTTGTAAATTCGTTATTACGATTATCGAGTTGGCTAGATAG
AAAACCGGAAATGTAATGGATGCCCTTTTCGAATAGCTGAGTTTCTTTGCCTAAAATAGC
CCAATATTGTTGCCCTTTTTCTATCACGAGGTTACTGAGCCATTGCATGAACGCGCGCGC
CTCGGCGGCTTTTTTTTTCTGCTGTGCTGTATAAAAGCGAAAAGCCAGAAGTTACTATCT
CGAATAAAAAACCCCTCGAACTGCCATCTCACTACCGAAA
Chr coordinates
Chr XIII from 7244-8383