Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
CDC5 Systematic Name
YMR001C Alias
MSD2, PKX2 Strain
S288c Description
Polo-like kinase essential for mitotic cell cycle; controls targeting, activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates shape of nucleus, expansion of nuclear envelope during mitosis; implicated in cell divisions in telomerase-negative strains through adaptation to DNA damage, which allows bypass of cell cycle arrest and contributes senescence-specific genome instability; human homologs PLK1, PLK3 can each complement cdc5 thermosensitive mutants External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA Hide Seq
>CDC5 YMR001C
ATGTCGTTGGGTCCTCTTAAAGCTATCAATGATAAGCAATTGAATACCCGTTCCAAGTTA
GTTCACACCCCAATAAAGGGAAATACCGCAGACCTCGTAGGAAAAGAAAATCACTTTAAA
CAAACAAAGAGACTAGATCCGAATAATGATCATCACCACCAGCCAGCTCAAAAAAAGAAA
AGGGAAAAGTTATCAGCTTTGTGTAAAACACCACCTTCATTAATCAAAACAAGAGGAAAA
GACTATCACCGAGGTCATTTTTTAGGTGAAGGTGGATTTGCTCGCTGTTTCCAAATTAAG
GACGATTCAGGCGAAATTTTTGCTGCCAAAACAGTTGCTAAAGCCTCAATTAAATCAGAG
AAGACAAGAAAAAAGTTGTTGTCGGAGATTCAAATTCATAAAAGTATGTCCCATCCAAAT
ATCGTTCAGTTTATTGATTGTTTTGAGGATGATAGCAATGTCTATATCTTATTGGAGATA
TGCCCCAACGGTTCATTAATGGAATTACTAAAAAGAAGAAAAGTTTTAACAGAACCAGAA
GTTAGATTTTTCACCACTCAAATATGTGGTGCAATTAAGTATATGCATTCAAGAAGAGTT
ATACATAGAGATTTAAAACTTGGTAACATCTTCTTCGATTCAAACTATAACTTAAAGATT
GGTGACTTCGGTCTGGCAGCTGTGTTGGCGAATGAAAGTGAACGTAAATACACCATATGC
GGAACACCTAATTACATCGCACCTGAAGTGTTGATGGGTAAGCATTCTGGACATTCATTT
GAAGTAGATATTTGGTCATTAGGTGTTATGCTTTATGCTTTGTTGATTGGTAAGCCACCC
TTCCAAGCAAGAGATGTAAACACTATTTATGAAAGAATCAAATGTCGTGATTTTTCGTTT
CCAAGAGATAAACCAATCTCAGATGAAGGTAAGATTTTAATAAGAGACATTCTATCCTTA
GATCCAATAGAAAGGCCCTCTTTGACTGAAATTATGGATTATGTATGGTTTAGGGGAACT
TTCCCACCATCTATTCCTTCGACGGTCATGTCAGAAGCACCAAATTTTGAGGATATTCCT
GAAGAGCAGTCACTGGTTAACTTCAAAGATTGCATGGAAAAATCTCTACTATTAGAAAGC
ATGAGCAGCGATAAAATTCAGCGTCAAAAGAGGGATTATATTTCTTCAATTAAATCTAGT
ATCGATAAACTAGAAGAGTACCACCAAAACAGACCATTTTTACCACATTCTTTATCCCCT
GGCGGGACGAAACAGAAATATAAGGAGGTTGTTGATATAGAGGCACAAAGAAGATTAAAC
GATTTGGCTCGTGAAGCAAGGATACGTAGAGCACAACAGGCCGTTTTGAGAAAAGAATTA
ATAGCTACATCGACCAATGTCATTAAATCAGAAATCTCCTTGAGAATATTAGCCAGTGAG
TGTCATCTTACTTTGAATGGCATTGTAGAAGCAGAAGCTCAGTATAAAATGGGAGGTCTT
CCGAAATCAAGATTGCCTAAAATTAAACACCCAATGATAGTTACCAAGTGGGTCGACTAC
TCCAACAAACACGGATTCTCCTATCAGTTATCAACAGAGGATATTGGTGTCTTATTTAAT
AATGGCACCACAGTTCTCCGATTGGCAGATGCAGAAGAGTTTTGGTATATTAGTTATGAC
GATCGGGAAGGTTGGGTAGCAAGTCATTATTTATTGAGCGAAAAACCACGAGAGCTAAGT
AGACATTTAGAAGTAGTTGATTTTTTTGCCAAGTACATGAAGGCAAATTTGAGCCGAGTA
TCTACGTTTGGCAGAGAAGAATATCATAAAGATGATGTATTTTTGAGAAGATACACAAGG
TATAAACCATTTGTTATGTTTGAACTAAGTGATGGTACTTTCCAGTTCAATTTCAAAGAT
CATCATAAAATGGCAATATCCGACGGAGGTAAATTGGTGACCTACATTTCTCCCTCCCAT
GAAAGCACCACATATCCCTTAGTTGAAGTACTAAAATATGGCGAGATCCCAGGATATCCA
GAAAGTAACTTTAGAGAGAAACTAACTTTGATAAAGGAAGGTTTGAAGCAGAAGTCCACA
ATTGTTACCGTAGATTAA Promoter Sequence
Download FASTA
>CDC5 YMR001C
TTAATCCTTTTTCTTAAAGGTTATAAACTGTACGAGTGATAGGCTTATATAGGTCGCGGA
GATTGCGGTGGAGTGAAAAAGCGCTTTTCTTTTATACCTTTGTTCAAGGTGGCGTTTGCC
GTATAAAAGCACACATGACATAACCGAACCTCGGAAAATGAAGTTGCACTGTTATTGCCT
TCCAGATGTGTAGAATCATCACCATCTTCTGTGATAAATGAAGAGGGAATCGTACGAGGA
CGCCAGCATATTTTTACATCAAAATTTATGTTATTGTTGAAGGAACATTGAAAAGATAGG
GCGGGCAAAATCTGCGATCAAGCCTATCCTCTTTCATCTCAGCTGTTCTAGATGCGTTAC
CCGGTGGTAACTTCACTGCATATTATTACTTTATATACCTTATTCTATATGTTGCCCGGG
TAGGGCATTATGTAGCATCACCCGGAAGAACTTTTGGACTTTTCTCTGTCAAAAGATATT
ACCTAAAAGGGTCAAAACAAAACAAACCCAATAAAGAAAATCCAAAATATAGAACGAATA
AATATCTCGAGGACCTGGGATGATCTTTGAATGTACATCCTTTGAAACAAGGCATATCTT
GAACAGTTACTCTTGTGCTACTCAACTTTCGTACAATACATATAGAATCACTGAGAAAGT
AAATCCAATTCAAGCGGCAGTTTCAAAGAACAATAAGCCTTTTGTGTCAAATTCTGATTC
TGCTTTTTTTCCTATTTTTTCATCCTTCAATTTTGTGGCATATACTACATTAACTTTCAA
GAAAACTTAAAAAAGAAAAGACAAAAAAGCTAAACTGCATAGTCAAGTTTGTATAATTGA
GCTGAGTATTATTTTTTGTACACAAAAACATTGGCTTTCTTATATCTTCTCTATATATAC
TCTCTTTCATTCATCGATAAACGTTACATTTGTTATTCATAGAGAATAAAAATCACAGCC
GTGGAGAAGAAAGAACAGAGTAAGATCAAGTCGAATAAAG
Chr coordinates
Chr XIII from 271136-269019
