Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
HOF1
Systematic Name
YMR032W
Alias
CYK2
Strain
S288c
Description
F-BAR protein that regulates actin cytoskeleton organization; binds and bundles actin filaments, linking them to septins; required for cytokinesis, actin cable organization, and secretory vesicle trafficking; regulates actomyosin ring dynamics and septin localization; N-term. half controls cell size and actin cable levels, while the C-term. half controls actin cable organization, inhibiting Bnr1p-mediated actin nucleation; forms axial striations/pillars at the bud neck; phosphorylated by Dbf2p
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>HOF1 YMR032W
ATGAGCTACAGTTATGAAGCTTGTTTTTGGGACCCAAACGACAATGGTGTGAACATCCTT
CTGGGTCACATTTCTCAGGGAATAAGATCTTGCGACTCAATGATACTTTTCTTTAAGCAG
CGTAGTGAGCTTGAGAAGGACTATGCCAGGCGGCTTGGAGCCATCACGGGAAAACTAGAC
AAAGACATTGGAACAAACATGGATTATGGAAAGTTGAATGAAACATTTAATGTGGTGCTC
AGTGTTGAGAAAGCTCGAGCACAATCGCATTCCAAGCAAAGTGAGATTCTTTTCAGACAG
ATTTACACGGATACTAAGGCATTTGCCGCTAACTTGCAAGCAAGATATACTACATTGAGT
GGAAAGATTGAAAGGTTGCGGATGGACAAGTTCAACAAGAAAAAGGGGTGTGAGGTGTTG
CAAAAGAAATTACAGGATGCCCAGATTAGATTCAGAGACTTGCAATTGAACGAGAATAAT
ATGATTGGGGCCAAGAGAGTAGAACACAACAAGAGAGAACTATTGAAATGGGAATCGAAC
TCTCAGGAATATAAGGTTCAACTAGACGTTCTTAAGCAAGAATATAAGGCATCGCAGAAA
TTCTGGATACACGAGTGGGCGCAATTATCCTGCGAACTGCAAGAAATGGAGAACGCTAGA
ATATCCTTTTTACAATCGAAATTACAACAGTTCGCAACCTCATCGATGGAAACATATATT
TTAGAGCAAACAAAAATGGACATGTTAACAAATCATCTGAACTCATTCACGGCAGCGGAT
GAAATATCGACGTTTTCAAAAGAAAATGGAACTGGTAGACTGAAACATAAGACTTCCAAA
GGTGACATGAATTCTAGCGCCAACTGGGCTCAAATGAGCAGTATCTCCACGACAAGTAAA
AAAACCGAATCGTATATGGACAATATAAGGAAACTATCTTCTCAGCTGAAGGAAACCGAA
AATAAAAGGAAACTAGCTTCAATAGACAAATATGAGAAACCATTGCCATCTCCAGAAGTC
ACCATGGCTACACAATTTAGAAATTCCACACCCGTCATACGTAATGAGACAAAAGTGGTT
GCTAACCCAACATTATCTTTGAGGTCTTCACCCGTCCAGTTACAGAGCAATGTGGATGAC
TCCGTGTTAAGGCAGAAACCTGATAAACCAAGGCCGATTGTTGGGGAAGAACAACTTAAA
CCTGATGAAGATTCGAAAAATCCTGATGAAAAAGGTCTAATGGTGCATAAAAGAAATCAA
TCTCTCAGCTCACCATCAGAATCAAGTTCTTCTAATCCAACGGATTTTAGCCACATCAAA
AAGAGACAAAGTATGGAATCTATGACTACATCCGTAAGTTCAATGGCCAATAGTATAGAC
GACTCACAGAGATTTGCCAAATCATGGAACTCGTCAAATAGGAAAAGAAAATCTATGAGC
CATTTGCAAGTACCCTCATCCGCTTCTTCGAGGTCGGATGATGGGGGAAGAACGCCTAAC
TCTGCGCACAACCTCAATGAAGATGATTATAACACGAGGAGAGATACCAGTACAAGCACA
ATTTTGTTCAAACCTCCTGTGGCAGTAAGAGGAACGTCTAGGGGGCACACGCATAGACAA
TCCATGATAATGCAAGATTCAAGTAATCCAATTGAAGATGCCTTGTACGAAATGGAAAGA
ATCCAAAGTAGTTCTAAACCAGGTACAAAAACAGGAAACATCATGGATGAGAGAGGTGTG
GTCAGGGATAGAGGTATTACTGTTACCTTGCCTATTGTCACCAGTGAAGGTTTTCCAGTC
ATTGAATATGCCAAGGCCATGTATCCATTGATTGGAAATGAGGCACCTGGATTAGCGAAT
TTCCATAAGGGCGACTATCTGCTAATTACTGAGATTGTTAATAAAGATTGGTATAAAGGT
GAAGTTTATGATAATGACCGTATAGATAGAAATCATAGGATAGGATTAATTCCCTATAAT
TTCATTCAGCTACTGCATCAAGGTCTTTGA
Promoter Sequence
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>HOF1 YMR032W
TTGGACTTTCTCTTCGTCTGAGATTCTTTTGAAGTTTTAGAAGTAGCAGAAGTTATTGAG
TTGTTACGTACAACTTTGGGTCCCATTTTGGATGCAGCTTTAGTGGCATTAGGGTCAATA
AACATACGTTTGTAAGCTTCTACCGTGGTTTGATTGTCATGAGCTAAATTAGCTGCCTTG
TCGGAAGCTGCATGAGCGTCGCTGACGCCAATTGAGTAACTTTGGGCAGGTGACTGGTAA
ACCCCGTACTTCAACTTCGCCTTATATAAAGCCTCCCTGCTTAATGGTTCGCCTGTTGTC
TGGTATACCTTTGGTTTTCTCAAAGATTTAGAGCCGTGTTTCAGCGACTTTTTCGACGAA
GTTATAGACGAAGTCCTGCTCCCTCCACCAGAAGTCTTTCCTATATTATGTATGTCTCTA
TCTTCTACAGCTGAAATTAAAGACATTGGTTATTTTGCGTTGGTTCCCTATATGCAAAGC
TATTTAACAACTAAAGACTGTGTAATCGTCAGAGTGCACTATTTTGCTTCTTTTCAAAGT
AGCTGCCAAAGAGCTGAACCTTTAGGATCCACTGAATTAATAAACATTGGTGATATACTG
CAAGCAACAAGGAGTTCTCCCCATCGAGTGGCAGTAGTTCTTCCCCCTCTCGAGGGTGCC
CCTTTCGGTAGTTTGCGATTTTCTTCCAGAAGAGCACCGATTGCCCCATCCGGAAAGTAC
TATTTCCCTTTTGGGTAACAGCGGACCGAAGCGGAAGCGTTCGAGTAGCCGAGGTATATG
ATTTCCTCTTTGGGCAAGTTGTAAACAATAAATGGTAAAAAGTTATGAAATATATTCAAT
GGTAAAGGTCCATTTGATAAAGTACACATTCACTGTATGAGGGAAAGAGGAAAGCCAGCT
AGAGCATTTTTTTGGAGCAGGCGAGCAAACAATATAAAATACAAAGGCCTCGTGTGAGAC
TTGGAAAGTGTACTACTAATATTCAGAAAAAGGTGAAAGA
Chr coordinates
Chr XIII from 335298-337307