Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name CCS1
Systematic Name YMR038C
Alias CCS, LYS7
Strain S288c
Description Copper chaperone for superoxide dismutase Sod1p; involved in oxidative stress protection; Met-X-Cys-X2-Cys motif within N-terminus is involved in insertion of copper into Sod1p under conditions of copper deprivation; required for regulation of yeast copper genes in response to DNA-damaging agents; protein abundance increases in response to DNA replication stress; human homolog CCS can complement yeast ccs1 null mutant
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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>CCS1 YMR038C
ATGACCACGAACGATACATACGAGGCTACTTATGCCATTCCCATGCACTGTGAAAATTGC
GTGAATGATATAAAGGCATGCCTAAAAAATGTCCCAGGAATCAATTCATTGAATTTCGAT
ATAGAGCAACAAATAATGAGCGTGGAAAGCTCAGTAGCCCCTTCAACCATCATCAACACC
TTGCGAAACTGTGGTAAAGACGCCATCATAAGAGGCGCCGGGAAGCCGAATTCTTCCGCG
GTCGCTATCTTAGAGACCTTTCAAAAATATACTATAGACCAGAAAAAGGACACCGCCGTG
AGGGGCCTAGCAAGAATCGTTCAGGTTGGAGAGAATAAGACTCTTTTTGACATCACTGTA
AATGGCGTCCCAGAGGCGGGAAATTACCACGCCAGCATTCACGAGAAAGGCGACGTCTCC
AAGGGCGTGGAATCTACTGGTAAAGTTTGGCACAAGTTCGACGAACCCATTGAATGCTTC
AACGAGAGTGATTTGGGCAAGAACTTGTACAGTGGGAAGACCTTTCTGAGCGCTCCCTTG
CCAACATGGCAACTTATCGGCCGCAGCTTTGTCATTTCCAAGTCTCTGAACCACCCAGAA
AACGAGCCTTCCTCCGTTAAGGACTACTCATTTCTGGGAGTCATTGCGAGAAGCGCTGGT
GTGTGGGAAAATAATAAACAAGTGTGTGCGTGTACCGGAAAGACTGTTTGGGAAGAGAGA
AAAGATGCCTTGGCCAACAACATCAAATAG
Promoter Sequence
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>CCS1 YMR038C
ACGACGAATTGCTTAAGCACAGATTGAATATTGATGAAGCCTTGAGAAGGCTAGGATCCA
AGAGACCAAAAACCAAAATGGTTAGACTATTGTCCGACGACGAATATGAAGATGATAACA
ATAATGACAGTACTAATAACGACAAGGATAAAAACGGGAAGGACAAGAACAGCCCAAAGA
AGAGGAGAGAAGATAAGTCCAAAGCATCTAATGAGAGTCATGACTTGGAGCCACGTTCAA
AGAAGAAGAAACCTGCTCCACCTACTCTACTTCCACACGAGGAAAACATTCAAAACGCTG
AAAGAGAAGCCAATGCTACTTTGATCATCCCAGGCCAGGCAGGTAGGAAACAACAAGAGG
AACGCAAGCAAAAGGAAAAAGAAGAGGCAGAGGAGGCAAAGGCAAAAGCAGTTGCAGAAC
AAGAGAAAGAGGCAAAGGCAAAAGAAAAGATAGCTGAACCTGAACCTGAACCTGTACCCA
CACTTCAAGCTAAAAAAGAAGATATTGTCTCCAACATAAACGAGTCAAAAGATGCAAATT
CTAGTGACGAAGAATTTGCTCAAAGCTTGGAAGCTGAAATGAACAAGGCTGAAGACGACA
TAAGTGAAGAAGAATAATAGTCCTGGAAGTTGAGCTTGCTTATGTCAACGTCTTCCATCC
AACGAGCTTATTAGAGAATAAAAAAAAAAAAAAAGAAATAAAAATATATACTTTTCTGTT
TGTCAAATTCATTTTAACAATTCATATAATCAAATATGTGATTTATAATAACCAGACAAA
AGTTAATCTTGTACATTTCAGTATAATATACTATCAAAAAAAAATTTGCGCTTACTAAGC
ATTTTCCCCGTACAACTAGTACACAGTGAGAATGGAAGAGGGTAAAAATTCATTGTTCGG
AAAAATAATATATTAAAGGCAAGCCAAAAAAAAAAAATTTAGACTAAGAAAAGAATAAAG
ATATCTTTGCAAGGCAGAAACCCATTCGATCAGCACAAAA
Chr coordinates Chr XIII from 348260-347511
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