Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
UBX4
Systematic Name
YMR067C
Alias
CUI1
Strain
S288c
Description
UBX domain-containing protein that interacts with Cdc48p; involved in degradation of polyubiquitinated proteins via the ERAD (ER-associated degradation) pathway; modulates the role of the Cdc48p-Nplp-Ufd1p AAA ATPase complex in delivery of misfolded proteins to the proteasome; protein abundance increases in response to DNA replication stress; human ortholog ASPSCR1 partially complements the yeast null mutant
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>UBX4 YMR067C
ATGCCTATGGTTACCGTGAAGTATAACTTCCAACTTTTCAAATGTAAAGTTTCGTTGAAT
TCAACACTAAACGATGTGTTACACCAATCCATACAATTCTTTCAACTGCACACCTCGTCA
AACGACTGGTCATTGATACATTTGGATAAACCGGTGCCATTAGATTTGCCATGGAGGCTT
CTAAACTTACCAACGGGTGTCAACTTAGAATTATCTAAAAGTAGTAATTTTCCGGTGGCG
AATAAGACCAACCGCGAAGATATTCCATTCAATACGATCAAAATACGGTTTCAAATCCCA
GGAAGAGATTCCGTGGTTAAAGAAATGCCATCTGACCAACCAATTGCCCCTATCTTGCGA
CAGATGAGCGGCGCTGCGGGAGATGATTTTAAGATCCAGGTCTTTTCCAAGATAATAGAG
TTCAAAACAATTAAGGATGAGAATTTGACTCTCGAAAATTTAGGGATTCAGGAGCCTTCG
TCAGTTAGATTGATTTTTAATAATACATCTCATTCTGAGGGCATTAGCGCTAATAGCGCT
ATTCACCCAAAACAAACTCCCCCTACGATGACGAACCCGGAAACGGTTGCTTCACTACCA
CCTCACGAACTACATAAACCTTCTGTGTTTTTGCCCTCGGATGAGCCATTAGCAGTTATC
AAGGATCAAATCGAGGATGAAGAAGATTATGAATTGACAGTAGAACAAGCCAAGAAATAC
CAAAAAATGTTATCATCGAAGGCTGGTACTTTGGGTGGTCCTATTTTGACAAAGAGACTT
AGAGAGCAATCAGCCAACAACTTGCCAAAGAAAAATAAGGCTATATCTGAGTGTTTGCTG
AGAGTCAAGTTCCCCGATAGAAGCCATATTCAAATAGCATTCAAACCCAATGAAGACATG
CGTACAGTTTATAACGTCGTGTCGCAGTTCCTGATCGATGAGAACATGCCTTTTACGTTA
AACCAATCTCATCCTTTCAAACCCTTGGCTAAAGACGATAAGAAGCTACTGGATGACCTG
GAATTTGGCTCTAAAACAATGCTGCTTTTTGAAACAAATTCAAATTCTAATGGCCCATTA
ATAAAGGCTCATCTTTTGGAAGACGCACAAAAAATCACACACGAAACGAGGACAACCCCA
TCAGTTAATACGATAAATAAATCCAATCCACAGGGCCCTTCTGATAACGCTACAAGTATC
AAAAAGACTTTAAATAGAGTACCTAAATGGATGAAATTAAGTAAAAAATAA
Promoter Sequence
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>UBX4 YMR067C
GGTTTGCTCGTGCCCTTTCATTAATGCTAAATGCACACAGGTGTTTCCTTTAAAGGTTTT
TATTAGTTCATGCTTGTCGTGCCCCAGCTGAATTAAATACACGCATATAAGGTATCTTCC
ATGGTATGAGGCGTAATGTAATGAACTCCATCCGTTCTCTGAGTCTATGTTGGTTAGCAA
ATCCGGATTCCGTCGCAATAATCTTTTCACTATAAGTAAATTGCCTTCAATAATAGCCTC
CCGCAAGCGAACTGAGGGCTCTTTCAACATCTTTTGTTCAATATATCCTCTTTTCTAATG
GGCGTTTTTTTTTTTTATTTTTAGGGTCCAGTTGATTTATACATTTTCAATTGTACCAGA
TCAAAAAAGTCTAGAGGAAAAAAACGTAATTAAGACAGAAGAAAAAAAGTATCAACTCCG
GAATAACCGGGCCGCAAGAGAAATCAAACAATTAGTTGCACGAACATTTTTATCAGGAAT
AAGCAGGTAAGGGTAGGTATAAAGGTCAGCTCAGTACACGTATATCGTGTGAGTTATCTT
TATTAAAATAATGATTCCAGAATAAGCGATGAGAGAGTAACGCTATTGGAATATGATATG
GGAAATATCTTGAAACAATTTCAATAATTTGTCCATGTTTATGCAGTGTTGTACAAGCGT
TTTTAAAGAAACTGTATAATATTCAAGATAGCGGGCGCCTCAACCGCTGTTTTGCTCCTC
TTTTCTCTTGGAACTCTTGCCAAGAAAGATGTACGCCTTATAAAACGCTAGATGCTATTT
CTTGCAACTTTATTACAAAATTTCAGCACTATTTCTTGCAATCCTAGATGTTTCCCTGTC
TTCTATCTTCGATGTTAATTTAGACGTTTCTTCAAAGATTCAAGTTCTCTTTTATTGTAC
TATGTGTGGCAAAAAAAAAAGAAAACCAAAAAATGCAAAAACTAAGATAAATCTACGTAC
TGCGAAGAATAGCAAGGCAGACTAATAAGCGCACAATACA
Chr coordinates
Chr XIII from 405573-404323