S.cerevisiae - Yeastract

Locus Information

Standard Name	YTA12
Systematic Name	YMR089C
Alias	RCA1
Strain	S288c
Description	Mitochondrial inner membrane m-AAA protease component; mediates degradation of misfolded or unassembled proteins; also required for correct assembly of mitochondrial enzyme complexes; overexpression of human AFG3L2 complements respiratory defect of yeast afg3 yta12 double null mutation, but overexpression of disease-associated AFG3L2 variants does not; expression of both human SPG7 (paraplegin) and AFG3L2 complements yeast yta12 afg3 double mutation
External sources	Open in SGD Open in KEGG

Gene Sequence Download FASTA View Seq	Sequence hidden
Promoter Sequence Download FASTA	>YTA12 YMR089C ACAGCGCGATACAATTTTCGTACTAAACAATCACAGAGGTAACAGCAAAGTTTGGAAAGT ACTTTTGTTGGAAAGTTATTACGGCCACTAACATTGTCTCGTCGTATTATTAAAAGCTAT AACGTCGTATTTCTTTGCTCGCTTGTGTTTTGTGATACAGGAAACACACACCAACAGGTT CACCGAGGGCTGTTGTCTGTCTTTGTACTTTAACTCAAAGAACTTCTGTTTCACGATTTG TATTAATAGTTCTTGCAGGCTACTAGGCTGAATACGTTAAAATGGTTAGCAACGAATATA ACCAGAAATACTTCGGGTACAATTCTGATACGTATATTTGTAGATATGTCTCGCTTGATG TTGCCAACTTTGTCAAAAATGGTAACGTATGGGCACACGGAATGTGCTAATCCTCGACTT TGCTCTTTCGTAAACCAATTTGATGCAAGTGCAGCGTGGTCTTTTGAAAGTGCATTATCT CATTGGGCGATGCGAAAACTCTGCCTACAGAAGTTCGCCGTTAGATAATTCTGATTGTAG AAAACCTACCAAAGAGAATAAACTAAAGTGTCATCTGCTAATTTATGATCTTATCGTCTG AGTGATGATGTATGTTTCTCTTTGTACGGTTCGTCTTGTGCTCATGTACGTAACATCCTC CATATGTGTGAATTATTTTGTCCGGCGTCTTGTTTGAATATCCCATCCGGACGTATTTCT TTATAGGATAACGCATGCACATATCGGTTCGTTCAATAAGAAAGTCCCTTCTGGTATTAT TCGGTGTCCTGTAAGATCTATATACTAATCACCAAGCTATCTGGTGTCACATTGTGAATA CATTTGTCTTTTGGTCCATTTTTCCCCATCATTTTCTCGTGAAAACGATCTCTAACTTTT GCCACTATAGTTTTAAAGGAAAGATTTTGAGCTGCCAACGAATACAATATAGCACACTCA AGAGTCTTGGCAAGCAACTTTAAAGTTAGAAAGAGTACTA
Chr coordinates	Chr XIII from 448086-445609