S.cerevisiae - Yeastract

Locus Information

Standard Name	YTA12
Systematic Name	YMR089C
Alias	RCA1
Strain	S288c
Description	Mitochondrial inner membrane m-AAA protease component; mediates degradation of misfolded or unassembled proteins; also required for correct assembly of mitochondrial enzyme complexes; overexpression of human AFG3L2 complements respiratory defect of yeast afg3 yta12 double null mutation, but overexpression of disease-associated AFG3L2 variants does not; expression of both human SPG7 (paraplegin) and AFG3L2 complements yeast yta12 afg3 double mutation
External sources	Open in SGD Open in KEGG

Gene Sequence Download FASTA Hide Seq	>YTA12 YMR089C ATGTTGCTACTTTCTTGGTCAAGAATTGCTACTAAGGTAGTTAGAAGGCCCGTTCGCTTC CGGTCCTATTACGGCTTGACCCATATCAAGAGTTTACATACTCAATATCGGCTACTCAAT AGGCTGCAAGAGAATAAGAGCGGTAACAAGAACGAGGACAATAACGAAGACGCTAAACTT AACAAAGAAATTCCCACAGACGAAGAGGTTGAAGCAATAAGAAAACAAGTAGAAAAATAT ATCGAACAAACTAAAAATAATACTATACCGGCTAACTGGAAAGAACAGAAACGCAAAATT GATGAAAGTATTAGGCGTTTAGAAGATGCTGTATTGAAACAAGAATCTAACAGAATTCAA GAAGAAAGAAAGGAAAAAGAGGAGGAAAATGGTCCTTCAAAAGCCAAGTCAAACAGAACA AAAGAGCAGGGCTACTTTGAAGGTAACAATAGCAGAAATATTCCACCGCCACCACCACCT CCTCCCCCAAAACCACCTCTAAATGATCCTAGTAATCCTGTATCGAAAAATGTTAACTTA TTCCAGATAGGACTAACTTTTTTCCTCCTTTCGTTTTTATTGGATCTCCTCAACAGTTTG GAAGAGCAAAGTGAGATAACGTGGCAGGATTTTAGAGAGAAACTATTGGCAAAAGGTTAT GTTGCGAAGTTGATTGTTGTCAACAAGTCCATGGTGAAAGTGATGTTAAATGACAACGGA AAAAACCAAGCCGACAATTACGGTCGCAACTTCTATTATTTCACAATTGGTTCAATTGAT AGCTTCGAACACAAACTTCAGAAAGCACAGGACGAACTGGACATTGATAAGGATTTCAGA ATACCTGTACTATATGTTCAAGAAGGCAATTGGGCTAAAGCTATGTTCCAAATTTTGCCA ACTGTTTTAATGATTGCAGGTATTATTTGGTTGACAAGAAGATCGGCACAAGCAGCGGGC GGTAGCCGTGGAGGCATATTTGGTCTGAGTCGTTCTAAGGCTAAAAAATTTAACACTGAA ACAGACGTTAAGATCAAGTTCAAGGACGTTGCCGGATGCGATGAGGCTAAGGAAGAAATT ATGGAGTTTGTTAGCTTCTTGAAAGAACCTTCTCGTTATGAAAAAATGGGAGCTAAAATT CCTAGAGGTGCGATTCTATCTGGTCCACCAGGTACCGGTAAAACTTTGCTTGCAAAGGCA ACAGCAGGTGAAGCCGGTGTTCCGTTTTATTTTGTTTCTGGTTCAGAATTTGTAGAAATG TTTGTTGGTGTTGGTGCAGCAAGAGTAAGAGATTTGTTCAAAACTGCAAGAGAAAATGCA CCCTCAATTGTGTTTATTGACGAAATTGATGCTATAGGAAAAGCAAGACAAAAGGGTAAT TTTTCAGGTGCCAATGATGAGAGAGAGAACACGCTAAATCAAATGTTAGTAGAAATGGAT GGTTTCACTCCAGCTGACCACGTTGTTGTTTTAGCTGGTACCAATAGACCCGATATTCTC GATAAAGCATTATTAAGGCCTGGTAGATTTGACAGGCATATCAATATCGACAAGCCCGAA CTTGAGGGTAGAAAAGCCATTTTTGCTGTTCATTTACATCATTTGAAACTTGCCGGGGAA ATTTTTGATTTGAAAAATAGATTAGCGGCTTTGACGCCAGGCTTTTCTGGTGCTGATATT GCCAACGTTTGTAACGAGGCCGCCTTGATTGCTGCTAGAAGTGATGAAGATGCAGTAAAA TTGAATCATTTTGAACAAGCTATCGAAAGAGTCATCGGTGGAGTGGAACGCAAATCCAAG CTACTCTCTCCCGAAGAGAAGAAAGTAGTGGCTTACCACGAGGCTGGTCATGCTGTATGT GGATGGTACTTAAAATACGCAGATCCTCTTCTGAAAGTCAGTATTATTCCACGTGGCCAG GGCGCCCTTGGTTATGCACAGTATTTGCCAGGTGATATCTTCTTACTAACTGAACAGCAA CTTAAGGACAGAATGACCATGTCTCTGGGTGGAAGAGTTTCTGAAGAATTACATTTCCCA TCAGTTACAAGTGGCGCATCTGATGACTTCAAAAAAGTTACTAGCATGGCCACGGCAATG GTCACAGAATTAGGCATGAGTGATAAAATTGGCTGGGTCAATTACCAGAAGAGAGATGAT AGCGATTTGACAAAACCATTTTCGGACGAGACAGGTGACATTATTGATTCCGAAGTATAC AGAATCGTCCAAGAATGCCATGACAGATGTACAAAGCTGCTTAAAGAAAAAGCAGAAGAT GTAGAGAAGATTGCTCAAGTACTACTGAAAAAAGAAGTTTTGACAAGAGAAGATATGATT GATTTACTTGGTAAGCGCCCTTTCCCAGAAAGGAATGATGCTTTTGATAAGTACTTGAAC GATTACGAAACGGAAAAAATCAGGAAGGAAGAAGAAAAAAACGAAAAACGTAATGAGCCT AAGCCATCTACAAACTGA
Promoter Sequence Download FASTA	>YTA12 YMR089C ACAGCGCGATACAATTTTCGTACTAAACAATCACAGAGGTAACAGCAAAGTTTGGAAAGT ACTTTTGTTGGAAAGTTATTACGGCCACTAACATTGTCTCGTCGTATTATTAAAAGCTAT AACGTCGTATTTCTTTGCTCGCTTGTGTTTTGTGATACAGGAAACACACACCAACAGGTT CACCGAGGGCTGTTGTCTGTCTTTGTACTTTAACTCAAAGAACTTCTGTTTCACGATTTG TATTAATAGTTCTTGCAGGCTACTAGGCTGAATACGTTAAAATGGTTAGCAACGAATATA ACCAGAAATACTTCGGGTACAATTCTGATACGTATATTTGTAGATATGTCTCGCTTGATG TTGCCAACTTTGTCAAAAATGGTAACGTATGGGCACACGGAATGTGCTAATCCTCGACTT TGCTCTTTCGTAAACCAATTTGATGCAAGTGCAGCGTGGTCTTTTGAAAGTGCATTATCT CATTGGGCGATGCGAAAACTCTGCCTACAGAAGTTCGCCGTTAGATAATTCTGATTGTAG AAAACCTACCAAAGAGAATAAACTAAAGTGTCATCTGCTAATTTATGATCTTATCGTCTG AGTGATGATGTATGTTTCTCTTTGTACGGTTCGTCTTGTGCTCATGTACGTAACATCCTC CATATGTGTGAATTATTTTGTCCGGCGTCTTGTTTGAATATCCCATCCGGACGTATTTCT TTATAGGATAACGCATGCACATATCGGTTCGTTCAATAAGAAAGTCCCTTCTGGTATTAT TCGGTGTCCTGTAAGATCTATATACTAATCACCAAGCTATCTGGTGTCACATTGTGAATA CATTTGTCTTTTGGTCCATTTTTCCCCATCATTTTCTCGTGAAAACGATCTCTAACTTTT GCCACTATAGTTTTAAAGGAAAGATTTTGAGCTGCCAACGAATACAATATAGCACACTCA AGAGTCTTGGCAAGCAACTTTAAAGTTAGAAAGAGTACTA
Chr coordinates	Chr XIII from 448086-445609