Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name YKU80
Systematic Name YMR106C
Alias HDF2
Strain S288c
Description Subunit of telomeric Ku complex (Yku70p-Yku80p); involved in telomere length maintenance, structure and telomere position effect; required for localization of telomerase ribonucleoprotein via interaction with TLC1 guide RNA; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair; colocalizes with quiescent cell telomere hyperclusters
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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>YKU80 YMR106C
ATGTCAAGTGAGTCAACAACTTTCATCGTGGATGTTTCACCATCAATGATGAAAAATAAT
AATGTTTCCAAATCTATGGCATATCTAGAGTACACTCTATTAAACAAATCTAAAAAAAGT
AGAAAAACAGATTGGATAAGCTGTTATCTCGCTAATTGTCCCGTATCTGAGAATTCCCAG
GAAATACCAAATGTGTTCCAAATACAATCCTTTTTGGCTCCTGTTACCACGACGGCCACC
ATTGGGTTTATAAAACGCCTGAAACAATATTGTGATCAGCACAGTCATGATAGTTCGAAT
GAAGGCTTACAATCAATGATTCAATGTCTGTTGGTCGTCTCATTAGATATTAAACAACAA
TTTCAAGCAAGAAAAATTCTAAAACAAATTGTTGTATTTACAGACAATTTAGATGATCTG
GATATTACTGATGAAGAAATAGACCTGCTAACGGAAGAATTAAGCACAAGAATCATTTTG
ATTGATTGCGGTAAAGACACTCAAGAGGAGAGGAAAAAATCGAACTGGTTAAAGTTGGTC
GAAGCGATACCGAATTCAAGAATCTACAATATGAATGAACTTCTTGTTGAAATCACTTCC
CCAGCAACATCTGTCGTTAAGCCAGTAAGAGTATTCTCAGGCGAGCTTAGGTTAGGGGCA
GATATATTATCAACACAAACATCGAATCCTAGCGGCAGCATGCAAGATGAAAATTGCTTA
TGTATCAAGGTAGAGGCTTTTCCTGCTACGAAAGCAGTTTCAGGCTTAAATAGGAAAACC
GCTGTTGAGGTGGAAGACTCCCAGAAGAAAGAAAGGTATGTGGGGGTCAAATCCATAATC
GAATATGAAATTCACAACGAAGGAAATAAGAAAAATGTCAGTGAAGATGACCAGTCTGGA
TCGTCATACATTCCCGTGACCATCTCCAAAGACTCTGTAACGAAGGCATACCGTTATGGT
GCAGACTACGTAGTGCTACCGTCCGTTCTAGTCGATCAAACTGTATATGAATCTTTTCCA
GGCTTGGATTTAAGAGGATTTTTGAATAGAGAAGCTCTTCCAAGGTACTTTTTGACGTCG
GAATCCTCCTTCATTACCGCCGACACAAGACTTGGCTGTCAATCTGACTTAATGGCTTTC
AGTGCTCTAGTGGATGTTATGCTAGAAAATAGAAAAATTGCTGTTGCAAGATATGTGAGC
AAGAAAGACAGTGAAGTGAATATGTGTGCATTGTGTCCCGTTCTAATTGAGCACAGTAAC
ATTAATTCCGAGAAGAAGTTTGTTAAGAGCCTTACCTTGTGTAGATTACCATTCGCGGAA
GACGAGAGGGTAACTGATTTTCCAAAACTTCTGGATCGAACAACTACATCCGGGGTACCG
CTGAAAAAGGAAACAGACGGGCATCAAATCGATGAGCTTATGGAACAATTTGTAGATTCA
ATGGATACAGATGAGCTACCAGAGATTCCGTTAGGCAACTACTATCAACCCATAGGCGAA
GTAACAACAGACACCACTCTCCCACTTCCCTCTTTAAATAAAGACCAAGAGGAAAACAAA
AAGGATCCTCTTAGAATACCCACGGTTTTTGTCTACAGGCAACAACAGGTGCTACTGGAA
TGGATTCACCAACTGATGATCAATGATTCCAGGGAATTTGAAATCCCAGAGCTTCCTGAC
TCATTGAAAAACAAAATAAGTCCTTACACGCACAAGAAATTTGATAGCACAAAATTGGTT
GAAGTGCTCGGCATCAAGAAAGTAGACAAATTAAAACTCGACTCCGAACTAAAAACTGAG
CTTGAGAGGGAAAAGATCCCGGACCTAGAAACGCTATTGAAGCGCGGTGAACAACACAGT
AGGGGAAGTCCAAACAATAGCAATAATTAA
Promoter Sequence
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>YKU80 YMR106C
CGGTTAAACGTTAGCGTGTTCTTCATTGCCTGTGGATGAGGATGAGCGCCGGTGCAAACT
TTCAAGTTTTTCGAGAGCGTCTTCAAACTTAGCTACCACATTGTTGTCTACATCAACAAA
AGTATGGTTCCATACTAAACTACCATCTTCTTTATTGCCGCTTAATTGTAACACGTCTAC
ATTACCAGAATGATGAACTCCGCCTGTCAGATAGTCGTGCTTTGGTGCGGTCTTGATAAA
ATTGTTGATTGCTTCCATCGATATCATGATTCAGCCTAGGATTTGTGGGTTGCTTTGATT
GATTGGAAATGATCGACTATGAGACCTTGAACCAGTTTAATTTTAAAATAAATATTTTTG
TTGAACTAGTTCAGCAACCGAAATCCAGAAAAAAAGTTCTAGAAGAATAGTTTTATTAAC
TTTGAGAAAGTAAAAGCTGAGATAAAAAACCAGCTCAACATATAAGAATACAAGCTGACG
GTAAATAACAATAAGTAGCCTTGTTGGCGCAATCGGTAGCGCGTATGACTCTTAATCATA
AGGTTAGGGGTTCGAGCCCCCTACAGGGCTTCTTTTTTTGAAGATTCAAGTAAATATGCT
GCATACATAATTCTCATTCAAAATATATACACTTAAGACATCTGGCCTTTTCTAGTTAAT
CTATATATTTAGTTCTTATAATAGATGAATGTACCGTCAACCAAAGATTAGCAGTTGGAG
GGCGTTAAAAACAATTTACCATTGCCAGGATTCGACAACACTATTGTAACGTATTTCTGT
TTCTGGTCTTGGAGTAATGTTTGTAGTCTATTAGCGGAAGTACCTTTTTACAGTGTCGAC
ACAATTTGACTATTTTTTCAACTAGATTACCGCATGTCCGTCAGGGCATTTGTTGTCATG
CAAAAAAATGAATAAAAAAAAAGGGCATCATCAAGAGAAGAAAACCTAATTAACGAGAGT
GCAGGACATATGCACAAATAATATATCTCACACCATAATA
Chr coordinates Chr XIII from 480190-478301
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