Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
HFD1
Systematic Name
YMR110C
Strain
S288c
Description
Dehydrogenase involved in ubiquinone and sphingolipid metabolism; converts 4-hydroxybenzaldehyde into 4-hydroxybenzoate for ubiquinone anabolism, hexadecenal to hexadecenoic acid in sphingosine 1-phosphate catabolism; human homolog ALDH3A2, mutated in Sjogren-Larsson syndrome, can rescue yeast hfd1 mutant; human ALDH3A1, but not ALDH3A2, rescues pABA- respiratory growth phenotype of hfd1 null; data suggest that dual functions of Hfd1p have diverged in human ALDH3A1, ALDH3A2
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>HFD1 YMR110C
ATGTCAAACGACGGCTCAAAAATATTGAATTATACCCCAGTGTCTAAAATAGATGAAATA
GTTGAAATCTCAAGAAATTTCTTCTTTGAGAAACAATTGAAATTGTCCCACGAAAATAAC
CCAAGGAAAAAAGATCTAGAATTCAGGCAGTTGCAGTTGAAAAAACTCTATTATGCCGTC
AAAGATCATGAGGAAGAACTGATCGATGCTATGTACAAGGACTTTCATCGGAACAAAATT
GAATCGGTTCTGAATGAAACGACCAAACTTATGAACGATATACTTCACCTAATTGAGATT
TTACCAAAATTGATCAAACCTCGGAGAGTATCTGATTCTTCTCCTCCATTTATGTTTGGT
AAAACAATCGTGGAGAAAATATCAAGGGGCAGTGTCTTGATTATTGCTCCTTTCAATTTT
CCCCTACTTTTAGCATTTGCCCCATTGGCAGCAGCTCTTGCTGCAGGTAACACCATTGTT
CTGAAGCCAAGTGAACTAACACCACACACTGCTGTAGTTATGGAAAATTTGTTAACCACA
GCTGGTTTCCCTGATGGATTGATTCAAGTAGTTCAGGGAGCTATAGATGAAACTACAAGA
CTACTAGATTGTGGAAAATTTGACCTAATATTCTACACAGGTTCTCCCCGTGTCGGATCA
ATAGTTGCTGAGAAAGCAGCAAAAAGTCTAACACCTTGTGTACTTGAACTTGGTGGTAAA
TCACCTACCTTTATTACAGAAAATTTCAAAGCAAGTAACATAAAAATTGCTTTGAAAAGG
ATTTTTTTTGGTGCTTTCGGAAATTCTGGCCAGATTTGTGTTTCACCAGATTATTTGTTA
GTACATAAATCTATCTATCCAAAAGTCATTAAAGAGTGTGAATCAGTACTAAATGAATTT
TATCCAAGCTTTGATGAACAAACAGATTTCACTCGTATGATTCATGAGCCTGCTTACAAA
AAGGCCGTTGCAAGTATAAACTCAACTAACGGCTCCAAGATTGTGCCTTCAAAAATTTCT
ATCAATTCAGATACTGAGGATCTATGCCTTGTACCACCAACCATAGTTTATAACATTGGT
TGGGATGATCCTTTGATGAAACAGGAAAACTTTGCTCCTGTATTGCCCATCATTGAGTAC
GAGGATCTTGATGAGACCATTAACAAGATAATAGAAGAACATGACACTCCATTGGTGCAA
TACATATTCTCTGATAGCCAAACTGAAATAAATCGTATCTTGACGCGCTTAAGATCTGGT
GACTGTGTTGTCGGTGATACAGTGATTCATGTAGGAATTACCGACGCTCCATTTGGAGGG
ATCGGTACTTCAGGTTATGGTAACTATGGTGGATATTATGGATTCAATACCTTTAGTCAT
GAAAGAACAATTTTTAAACAACCATATTGGAATGATTTTACCCTTTTTATGAGATACCCT
CCAAATAGCGCACAAAAGGAAAAGCTCGTCCGTTTTGCGATGGAAAGAAAACCTTGGTTT
GACAGAAATGGCAATAACAAGTGGGGGTTACGCCAATATTTTTCATTATCTGCCGCCGTT
ATTTTAATTAGTACCATTTACGCTCATTGTTCTTCCTGA
Promoter Sequence
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>HFD1 YMR110C
CAATGCTGATGACAGTAATAACCAACTCGATGGAACAGGAAACGAGAATGATATCAGAAA
CAGAAGAGGGTGCGTTGGAACGTCATATAAACTAAATCGTGCAATCCAGAACGTTACAGA
TGCGGCCCGTGAATACTTTGAAGGCTTACCGGGCCAACCGTCAGTTCTTTCCCTTGAGAG
GAGATATGGGTCCACTTGGAGGCGATCTGCCAAAGAAAGGACTTTGTTCACTAAAAGAAT
GACCATCATAAAAAGAATAATAGATATAAAAGATGATCCAAGCAAATATGGTTTGTCGCT
ACCTGAGAATAAAATAAGTAGAAACCAAGCCATCAAGGTTGTCGAAAATATAAGATTGGG
AAACAATACCTTCAAAGGACATCATTGCCGATTATCAATGTCCCAGTTATACGAATACTT
CTCCAAAAAAATGGACAAACTCGAAGACTATTCACTTACTCTAAAGAGAAGAGGGAAGCC
AAGAAGAATTTTCTTGTTAGAAGAGAGAGAAGCTAGATTATCATTACAGCAGCCACATAG
TATACCAAATTCCAGTACAGGCACACCAGAACATGATCAAGACACTTAGAGGAAATGGAA
CAACGAATTTCCAGCCAAAAATTCCGAGTAGTTCATGATGAAAGATTTTTACATGCATTT
TATATATAAATATATACCGTCCTATATGGATTTCATGCCAACAGGGTATATAATAGACAA
TTACCGGTGTACTGATATATCAACTATCGACTCCAAGCCTTTTATCTATCAGTCAATTTT
ACATCAAGATCCCACTTTTAGATAGGTTCGAAAATTCAATCTAATATTAGTGATTTAATT
AGATGGTGGATTGCTTACCCTTTTTTTTGTCGTTTTAGGAGGAGATTCTTCGGATTTTAG
GGATAAACGGATACTCCATATATAAAAAACAAAACTTCAGGCATATTGATTATCTAAAAG
GAATATTCTAAAACCATAGCCATAGTAATTTATCACCAAC
Chr coordinates
Chr XIII from 491992-490394